메뉴 건너뛰기




Volumn 6, Issue 1, 2011, Pages 31-40

Towards drug discovery for brain tumours: Interaction of kinins and tumours at the blood brain barrier interface

Author keywords

Blood brain barrier; Bradykinin; CNS tumours; Glioma; Kinins; Substance P

Indexed keywords

BRADYKININ; KALLIKREIN; KININ DERIVATIVE; NEUROKININ; OPIATE AGONIST; SUBSTANCE P; TACHYKININ;

EID: 78650942039     PISSN: 15748898     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488911794079118     Document Type: Article
Times cited : (18)

References (120)
  • 2
    • 4344609724 scopus 로고    scopus 로고
    • The treatment of brain metastases in melanoma patients
    • Bafaloukos D, Gogas H. The treatment of brain metastases in melanoma patients. Cancer Treat Rev 2004; 30: 515-20.
    • (2004) Cancer Treat Rev , vol.30 , pp. 515-520
    • Bafaloukos, D.1    Gogas, H.2
  • 5
    • 0029398077 scopus 로고
    • An overview of radiotherapy trials for the treatment of brain metastases
    • Berk L. An overview of radiotherapy trials for the treatment of brain metastases. Oncology 1995; 9: 1205-12.
    • (1995) Oncology , vol.9 , pp. 1205-1212
    • Berk, L.1
  • 6
    • 67649086209 scopus 로고    scopus 로고
    • Current management of metastatic brain disease
    • Ranjan T, Abrey LE. Current management of metastatic brain disease. Neurotherapeutics 2009; 6: 598-603.
    • (2009) Neurotherapeutics , vol.6 , pp. 598-603
    • Ranjan, T.1    Abrey, L.E.2
  • 8
    • 0025177393 scopus 로고
    • The response of cerebral metastases in small cell lung cancer to systemic chemotherapy
    • Twelves CJ, Souhami RL, Harper PG, Ash CM, Spiro SG, Earl HM, et al. The response of cerebral metastases in small cell lung cancer to systemic chemotherapy. Br J Cancer 1990; 61: 147-50.
    • (1990) Br J Cancer , vol.61 , pp. 147-150
    • Twelves, C.J.1    Souhami, R.L.2    Harper, P.G.3    Ash, C.M.4    Spiro, S.G.5    Earl, H.M.6
  • 9
    • 2942594011 scopus 로고    scopus 로고
    • Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor
    • Black KL, Ningaraj NS. Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor. Cancer Control 2004; 11: 165-73.
    • (2004) Cancer Control , vol.11 , pp. 165-173
    • Black, K.L.1    Ningaraj, N.S.2
  • 10
    • 0031749973 scopus 로고    scopus 로고
    • Differential permeability of a human brain tumor xenograft in the nude rat: Impact of tumor size and method of administration on optimizing delivery of biologically diverse agents
    • Neuwelt EA, Barnett PA, McCormick CI, Remsen LG, Kroll RA, Sexton G. Differential permeability of a human brain tumor xenograft in the nude rat: Impact of tumor size and method of administration on optimizing delivery of biologically diverse agents. Clin Cancer Res 1998; 4: 1549-55.
    • (1998) Clin Cancer Res , vol.4 , pp. 1549-1555
    • Neuwelt, E.A.1    Barnett, P.A.2    McCormick, C.I.3    Remsen, L.G.4    Kroll, R.A.5    Sexton, G.6
  • 11
    • 21844442379 scopus 로고    scopus 로고
    • Hyperosmotic mannitol induces Src kinase-dependent phosphorylation of beta-catenin in cerebral endothelial cells
    • Farkas A, Szatmari E, Orbok A, Wilhelm I, Wejksza K, Nagyoszi P, et al. Hyperosmotic mannitol induces Src kinase-dependent phosphorylation of beta-catenin in cerebral endothelial cells. J Neurosci Res 2005; 80: 855-61.
    • (2005) J Neurosci Res , vol.80 , pp. 855-861
    • Farkas, A.1    Szatmari, E.2    Orbok, A.3    Wilhelm, I.4    Wejksza, K.5    Nagyoszi, P.6
  • 12
    • 0031720748 scopus 로고    scopus 로고
    • Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: A comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers
    • Kroll RA, Pagel MA, Muldoon LL, Roman-Goldstein S, Fiamengo SA, Neuwelt EA. Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: A comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers. Neurosurgery 1998; 43: 879-86.
    • (1998) Neurosurgery , vol.43 , pp. 879-886
    • Kroll, R.A.1    Pagel, M.A.2    Muldoon, L.L.3    Roman-Goldstein, S.4    Fiamengo, S.A.5    Neuwelt, E.A.6
  • 13
    • 0025261267 scopus 로고
    • Capillary permeability factor secreted by malignant brain tumor. Role in peritumoral brain edema and possible mechanism for anti-edema effect of glucocorticoids
    • Ohnishi T, Sher PB, Posner JB, Shapiro WR. Capillary permeability factor secreted by malignant brain tumor. Role in peritumoral brain edema and possible mechanism for anti-edema effect of glucocorticoids. J Neurosurg 1990; 72: 245-51.
    • (1990) J Neurosurg , vol.72 , pp. 245-251
    • Ohnishi, T.1    Sher, P.B.2    Posner, J.B.3    Shapiro, W.R.4
  • 14
    • 0029784688 scopus 로고    scopus 로고
    • Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor
    • Heiss JD, Papavassiliou E, Merrill MJ, Nieman L, Knightly JJ, Walbridge S, et al. Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor. J Clin Invest 1996; 98: 1400-8.
    • (1996) J Clin Invest , vol.98 , pp. 1400-1408
    • Heiss, J.D.1    Papavassiliou, E.2    Merrill, M.J.3    Nieman, L.4    Knightly, J.J.5    Walbridge, S.6
  • 15
    • 0035513543 scopus 로고    scopus 로고
    • Brain metastases: Biology and the role of the brain microenvironment
    • Puduvalli VK. Brain metastases: Biology and the role of the brain microenvironment. Curr Oncol Rep 2001; 3: 467-75.
    • (2001) Curr Oncol Rep , vol.3 , pp. 467-475
    • Puduvalli, V.K.1
  • 16
    • 0002603561 scopus 로고
    • Brain edema, Increased Intracranial Pressure, Vascular Effects, and other Epiphenomena of Human Brain Tumours
    • Edinburgh: Churchill Livingston
    • Thapar K, Rutka JT, Laws ER. Brain edema, Increased Intracranial Pressure, Vascular Effects, and other Epiphenomena of Human Brain Tumours. Brain Tumours: An Encyclopedic Approach. Edinburgh: Churchill Livingston 1995: 163-90.
    • (1995) Brain Tumours: An Encyclopedic Approach , pp. 163-190
    • Thapar, K.1    Rutka, J.T.2    Laws, E.R.3
  • 17
    • 0023684344 scopus 로고
    • Macrophage infiltration into experimental brain metastases: Occurrence through an intact blood-brain barrier
    • Schackert G, Simmons RD, Buzbee TM, Hume DA, Fidler IJ. Macrophage infiltration into experimental brain metastases: Occurrence through an intact blood-brain barrier. J Natl Cancer Inst 1988; 80: 1027-34.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 1027-1034
    • Schackert, G.1    Simmons, R.D.2    Buzbee, T.M.3    Hume, D.A.4    Fidler, I.J.5
  • 18
    • 0028064746 scopus 로고
    • Vascular permeability factor in brain metastases: Correlation with vasogenic brain edema and tumor angiogenesis
    • Strugar J, Rothbart D, Harrington W, Criscuolo GR. Vascular permeability factor in brain metastases: Correlation with vasogenic brain edema and tumor angiogenesis. J Neurosurg 1994; 81: 560-6.
    • (1994) J Neurosurg , vol.81 , pp. 560-566
    • Strugar, J.1    Rothbart, D.2    Harrington, W.3    Criscuolo, G.R.4
  • 19
    • 0024444606 scopus 로고
    • Ultrastructure of capillary walls in human brain tumors
    • Shibata S. Ultrastructure of capillary walls in human brain tumors. Acta Neuropathol 1989; 78: 561-71.
    • (1989) Acta Neuropathol , vol.78 , pp. 561-571
    • Shibata, S.1
  • 20
    • 0016701895 scopus 로고
    • Vascular structures in brain tumors
    • Hirano A, Matsui T. Vascular structures in brain tumors. Hum Pathol 1975; 6: 611-21.
    • (1975) Hum Pathol , vol.6 , pp. 611-621
    • Hirano, A.1    Matsui, T.2
  • 21
    • 0027845515 scopus 로고
    • The genesis of peritumoral vasogenic brain edema and tumor cysts: A hypothetical role for tumor-derived vascular permeability factor
    • Criscuolo GR. The genesis of peritumoral vasogenic brain edema and tumor cysts: A hypothetical role for tumor-derived vascular permeability factor. Yale J Biol Med 1993; 66: 277-314.
    • (1993) Yale J Biol Med , vol.66 , pp. 277-314
    • Criscuolo, G.R.1
  • 22
    • 0030795230 scopus 로고    scopus 로고
    • Hematogenous metastases of the human brain-characteristics of peritumoral brain changes: A review
    • Zhang M, Olsson Y. Hematogenous metastases of the human brain-characteristics of peritumoral brain changes: A review. J Neurooncol 1997; 35: 81-9.
    • (1997) J Neurooncol , vol.35 , pp. 81-89
    • Zhang, M.1    Olsson, Y.2
  • 23
    • 0026440587 scopus 로고
    • Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice
    • Zhang RD, Price JE, Fujimaki T, Bucana CD, Fidler IJ. Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am J Pathol 1992; 141: 1115-24.
    • (1992) Am J Pathol , vol.141 , pp. 1115-1124
    • Zhang, R.D.1    Price, J.E.2    Fujimaki, T.3    Bucana, C.D.4    Fidler, I.J.5
  • 24
    • 0018745296 scopus 로고
    • Capillary ultrastructure in human metastatic brain tumors
    • Long DM. Capillary ultrastructure in human metastatic brain tumors. J Neurosurg 1979; 51: 53-8.
    • (1979) J Neurosurg , vol.51 , pp. 53-58
    • Long, D.M.1
  • 25
    • 0032435594 scopus 로고    scopus 로고
    • Pharmacological reactivity of neoplastic and non-neoplastic associated neovasculature to vasoconstrictors
    • Andrade SP, Beraldo WT. Pharmacological reactivity of neoplastic and non-neoplastic associated neovasculature to vasoconstrictors. Int J Exp Pathol 1998; 79: 425-32.
    • (1998) Int J Exp Pathol , vol.79 , pp. 425-432
    • Andrade, S.P.1    Beraldo, W.T.2
  • 26
    • 0034282780 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis
    • Yano S, Shinohara H, Herbst RS, Kuniyasu H, Bucana CD, Ellis LM, et al. Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis. Cancer Res 2000; 60: 4959-67.
    • (2000) Cancer Res , vol.60 , pp. 4959-4967
    • Yano, S.1    Shinohara, H.2    Herbst, R.S.3    Kuniyasu, H.4    Bucana, C.D.5    Ellis, L.M.6
  • 27
    • 0035851219 scopus 로고    scopus 로고
    • Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway
    • Silvestre JS, Bergaya S, Tamarat R, Duriez M, Boulanger CM, Levy BI. Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway. Circ Res 2001; 89: 678-83.
    • (2001) Circ Res , vol.89 , pp. 678-683
    • Silvestre, J.S.1    Bergaya, S.2    Tamarat, R.3    Duriez, M.4    Boulanger, C.M.5    Levy, B.I.6
  • 28
    • 0037174870 scopus 로고    scopus 로고
    • A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation
    • Duchene J, Schanstra JP, Pecher C, Pizard A, Susini C, Esteve JP, et al. A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation. J Biol Chem 2002; 277: 40375-83.
    • (2002) J Biol Chem , vol.277 , pp. 40375-4083
    • Duchene, J.1    Schanstra, J.P.2    Pecher, C.3    Pizard, A.4    Susini, C.5    Esteve, J.P.6
  • 29
    • 0028869860 scopus 로고
    • Kinins and kinin receptors in the nervous system
    • Walker K, Perkins M, Dray A. Kinins and kinin receptors in the nervous system. Neurochem Int 1995; 26: 1-16.
    • (1995) Neurochem Int , vol.26 , pp. 1-16
    • Walker, K.1    Perkins, M.2    Dray, A.3
  • 30
    • 16244385015 scopus 로고    scopus 로고
    • Targeting kinin receptors for the treatment of neurological diseases
    • Rodi D, Couture R, Ongali B, Simonato M. Targeting kinin receptors for the treatment of neurological diseases. Curr Pharm Des 2005; 11:1313-26.
    • (2005) Curr Pharm Des , vol.11 , pp. 1313-1326
    • Rodi, D.1    Couture, R.2    Ongali, B.3    Simonato, M.4
  • 31
    • 10844228161 scopus 로고    scopus 로고
    • Kinin B1 receptors: Key G-protein-coupled receptors and their role in inflammatory and painful processes
    • Calixto JB, Medeiros R, Fernandes ES, Ferreira J, Cabrini DA, Campos MM. Kinin B1 receptors: Key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol 2004; 143: 803-18.
    • (2004) Br J Pharmacol , vol.143 , pp. 803-818
    • Calixto, J.B.1    Medeiros, R.2    Fernandes, E.S.3    Ferreira, J.4    Cabrini, D.A.5    Campos, M.M.6
  • 32
    • 37549017669 scopus 로고    scopus 로고
    • Modulation of B1 and B2 kinin receptors expression levels in the hippocampus of rats after audiogenic kindling and with limbic recruitment, a model of temporal lobe epilepsy
    • Pereira MG, Gitai DL, Paco-Larson ML, Pesquero JB, Garcia-Cairasco N, Costa-Neto CM. Modulation of B1 and B2 kinin receptors expression levels in the hippocampus of rats after audiogenic kindling and with limbic recruitment, a model of temporal lobe epilepsy. Int Immunopharmacol 2008; 8: 200-5.
    • (2008) Int Immunopharmacol , vol.8 , pp. 200-205
    • Pereira, M.G.1    Gitai, D.L.2    Paco-Larson, M.L.3    Pesquero, J.B.4    Garcia-Cairasco, N.5    Costa-Neto, C.M.6
  • 33
    • 0026544583 scopus 로고
    • Bradykinin and neuronal injury
    • Francel PC. Bradykinin and neuronal injury. J Neurotrauma 1992; 9 (Suppl 1): S27-45.
    • (1992) J Neurotrauma , vol.9 , Issue.SUPPL. 1
    • Francel, P.C.1
  • 34
    • 18544374882 scopus 로고    scopus 로고
    • Kinin B1 receptor expression on multiple sclerosis mononuclear cells: Correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability
    • Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, et al. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: Correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Arch Neurol 2005; 62: 795-800.
    • (2005) Arch Neurol , vol.62 , pp. 795-800
    • Prat, A.1    Biernacki, K.2    Saroli, T.3    Orav, J.E.4    Guttmann, C.R.5    Weiner, H.L.6
  • 36
    • 0031755682 scopus 로고    scopus 로고
    • Neuropeptides: Mediators of inflammation and tissue repair?
    • Schaffer M, Beiter T, Becker HD, Hunt TK. Neuropeptides: Mediators of inflammation and tissue repair? Arch Surg 1998; 133: 1107-16.
    • (1998) Arch Surg , vol.133 , pp. 1107-1116
    • Schaffer, M.1    Beiter, T.2    Becker, H.D.3    Hunt, T.K.4
  • 37
    • 0035252096 scopus 로고    scopus 로고
    • Role of endocytosis in mediating downregulation of G-protein-coupled receptors
    • Tsao P, Cao T, von Zastrow M. Role of endocytosis in mediating downregulation of G-protein-coupled receptors. Trends Pharmacol Sci 2001; 22: 91-6.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 91-96
    • Tsao, P.1    Cao, T.2    von Zastrow, M.3
  • 39
    • 77955090446 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) inhibitors exacerbate histological damage and motor deficits after experimental traumatic brain injury
    • Harford-Wright E, Thornton E, Vink R. Angiotensin-converting enzyme (ACE) inhibitors exacerbate histological damage and motor deficits after experimental traumatic brain injury. Neurosci Lett 2010; 481: 26-9.
    • (2010) Neurosci Lett , vol.481 , pp. 26-29
    • Harford-Wright, E.1    Thornton, E.2    Vink, R.3
  • 40
    • 72949094390 scopus 로고    scopus 로고
    • Substance P antagonists as a therapeutic approach to improving outcome following traumatic brain injury
    • Vink R, van den Heuvel C. Substance P antagonists as a therapeutic approach to improving outcome following traumatic brain injury. Neurotherapeutics 2010; 7: 74-80.
    • (2010) Neurotherapeutics , vol.7 , pp. 74-80
    • Vink, R.1    van den Heuvel, C.2
  • 42
    • 77955089495 scopus 로고    scopus 로고
    • A Substance P mediated pathway contributes to 6-hydroxydopamine induced cell death
    • Thornton E, Tran TT, Vink R. A substance P mediated pathway contributes to 6-hydroxydopamine induced cell death. Neurosci Lett 2010; 481: 64-7.
    • (2010) Neurosci Lett , vol.481 , pp. 64-67
    • Thornton, E.1    Tran, T.T.2    Vink, R.3
  • 43
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 1998; 281: 1640-5.
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3    Shrivastava, R.4    Carman, J.5    Sramek, J.J.6
  • 49
    • 3042750282 scopus 로고    scopus 로고
    • The tissue kallikrein family of serine proteases: Functional roles in human disease and potential as clinical biomarkers
    • Clements JA, Willemsen NM, Myers SA, Dong Y. The tissue kallikrein family of serine proteases: Functional roles in human disease and potential as clinical biomarkers. Crit Rev Clin Lab Sci 2004; 41: 265-312.
    • (2004) Crit Rev Clin Lab Sci , vol.41 , pp. 265-312
    • Clements, J.A.1    Willemsen, N.M.2    Myers, S.A.3    Dong, Y.4
  • 50
    • 0035503704 scopus 로고    scopus 로고
    • CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression
    • Li B, Goyal J, Dhar S, Dimri G, Evron E, Sukumar S, et al. CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression. Cancer Res 2001; 61: 8014-21.
    • (2001) Cancer Res , vol.61 , pp. 8014-8021
    • Li, B.1    Goyal, J.2    Dhar, S.3    Dimri, G.4    Evron, E.5    Sukumar, S.6
  • 52
    • 37549037823 scopus 로고    scopus 로고
    • Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma
    • Singh J, Naran A, Misso NL, Rigby PJ, Thompson PJ, Bhoola KD. Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma. Int Immunopharmacol 2008; 8: 300-6.
    • (2008) Int Immunopharmacol , vol.8 , pp. 300-306
    • Singh, J.1    Naran, A.2    Misso, N.L.3    Rigby, P.J.4    Thompson, P.J.5    Bhoola, K.D.6
  • 53
    • 50849089897 scopus 로고    scopus 로고
    • Clinical outcomes after a diagnosis of brain metastases in patients with estrogen-and/or human epidermal growth factor receptor 2-positive versus triple-negative breast cancer
    • Hines SL, Vallow LA, Tan WW, McNeil RB, Perez EA, Jain A. Clinical outcomes after a diagnosis of brain metastases in patients with estrogen-and/or human epidermal growth factor receptor 2-positive versus triple-negative breast cancer. Ann Oncol 2008; 19: 1561-5.
    • (2008) Ann Oncol , vol.19 , pp. 1561-1565
    • Hines, S.L.1    Vallow, L.A.2    Tan, W.W.3    McNeil, R.B.4    Perez, E.A.5    Jain, A.6
  • 54
    • 0035071938 scopus 로고    scopus 로고
    • High incidence of central nervous system involvement in patients with metastatic or locally advanced breast cancer treated with epirubicin and docetaxel
    • Crivellari D, Pagani O, Veronesi A, Lombardi D, Nole F, Thurlimann B, et al. High incidence of central nervous system involvement in patients with metastatic or locally advanced breast cancer treated with epirubicin and docetaxel. Ann Oncol 2001; 12: 353-6.
    • (2001) Ann Oncol , vol.12 , pp. 353-356
    • Crivellari, D.1    Pagani, O.2    Veronesi, A.3    Lombardi, D.4    Nole, F.5    Thurlimann, B.6
  • 55
    • 0033777777 scopus 로고    scopus 로고
    • Asymptomatic brain metastases (BM) in small cell lung cancer (SCLC): MR-imaging is useful at initial diagnosis
    • Hochstenbag MM, Twijnstra A, Wilmink JT, Wouters EF, ten Velde GP. Asymptomatic brain metastases (BM) in small cell lung cancer (SCLC): MR-imaging is useful at initial diagnosis. J Neurooncol 2000; 48: 243-8.
    • (2000) J Neurooncol , vol.48 , pp. 243-248
    • Hochstenbag, M.M.1    Twijnstra, A.2    Wilmink, J.T.3    Wouters, E.F.4    ten Velde, G.P.5
  • 60
    • 33646558897 scopus 로고    scopus 로고
    • A role for substance P in cancer promotion and progression: A mechanism to counteract intracellular death signals following oncogene activation or DNA damage
    • Esteban F, Munoz M, Gonzalez-Moles MA, Rosso M. A role for substance P in cancer promotion and progression: A mechanism to counteract intracellular death signals following oncogene activation or DNA damage. Cancer Metastasis Rev 2006; 25: 137-45.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 137-145
    • Esteban, F.1    Munoz, M.2    Gonzalez-Moles, M.A.3    Rosso, M.4
  • 62
    • 34948856407 scopus 로고    scopus 로고
    • Substance P and its receptors-a potential target for novel medicines in malignant brain tumour therapies (mini-review)
    • Lazarczyk M, Matyja E, Lipkowski A. Substance P and its receptors-a potential target for novel medicines in malignant brain tumour therapies (mini-review). Folia Neuropathol 2007; 45: 99-107.
    • (2007) Folia Neuropathol , vol.45 , pp. 99-107
    • Lazarczyk, M.1    Matyja, E.2    Lipkowski, A.3
  • 63
    • 0029071971 scopus 로고
    • Substance-P receptors in human primary neoplasms: Tumoral and vascular localization
    • Hennig IM, Laissue JA, Horisberger U, Reubi JC. Substance-P receptors in human primary neoplasms: Tumoral and vascular localization. Int J Cancer 1995; 61: 786-92.
    • (1995) Int J Cancer , vol.61 , pp. 786-792
    • Hennig, I.M.1    Laissue, J.A.2    Horisberger, U.3    Reubi, J.C.4
  • 64
    • 0025092876 scopus 로고
    • Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells
    • Ziche M, Morbidelli L, Pacini M, Geppetti P, Alessandri G, Maggi CA. Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. Microvasc Res 1990; 40: 264-78.
    • (1990) Microvasc Res , vol.40 , pp. 264-278
    • Ziche, M.1    Morbidelli, L.2    Pacini, M.3    Geppetti, P.4    Alessandri, G.5    Maggi, C.A.6
  • 67
    • 0036498031 scopus 로고    scopus 로고
    • Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues
    • Wu J, Akaike T, Hayashida K, Miyamoto Y, Nakagawa T, Miyakawa K, et al. Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues. Int J Cancer 2002; 98(1): 29-35.
    • (2002) Int J Cancer , vol.98 , Issue.1 , pp. 29-35
    • Wu, J.1    Akaike, T.2    Hayashida, K.3    Miyamoto, Y.4    Nakagawa, T.5    Miyakawa, K.6
  • 68
    • 73949158706 scopus 로고    scopus 로고
    • Bradykinin increases the secretion and expression of endothelin-1 through kinin B2 receptors in melanoma cells
    • Andoh T, Akira A, Saiki I, Kuraishi Y. Bradykinin increases the secretion and expression of endothelin-1 through kinin B2 receptors in melanoma cells. Peptides 2010; 31: 238-41.
    • (2010) Peptides , vol.31 , pp. 238-241
    • Andoh, T.1    Akira, A.2    Saiki, I.3    Kuraishi, Y.4
  • 70
    • 77951722419 scopus 로고    scopus 로고
    • Bradykinin-induced cell migration and COX-2 production mediated by the bradykinin B1 receptor in glioma cells
    • Lu DY, Leung YM, Huang SM, Wong KL. Bradykinin-induced cell migration and COX-2 production mediated by the bradykinin B1 receptor in glioma cells. J Cell Biochem 2010; 110: 141-50.
    • (2010) J Cell Biochem , vol.110 , pp. 141-150
    • Lu, D.Y.1    Leung, Y.M.2    Huang, S.M.3    Wong, K.L.4
  • 73
    • 3442878400 scopus 로고    scopus 로고
    • Host stromal bradykinin B2 receptor signaling facilitates tumor-associated angiogenesis and tumor growth
    • Ikeda Y, Hayashi I, Kamoshita E, Yamazaki A, Endo H, Ishihara K, et al. Host stromal bradykinin B2 receptor signaling facilitates tumor-associated angiogenesis and tumor growth. Cancer Res 2004; 64: 5178-85.
    • (2004) Cancer Res , vol.64 , pp. 5178-5185
    • Ikeda, Y.1    Hayashi, I.2    Kamoshita, E.3    Yamazaki, A.4    Endo, H.5    Ishihara, K.6
  • 74
    • 0029961467 scopus 로고    scopus 로고
    • Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogenactivated protein kinase signaling pathway
    • Luo W, Sharif TR, Sharif M. Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogenactivated protein kinase signaling pathway. Cancer Res 1996; 56: 4983-91.
    • (1996) Cancer Res , vol.56 , pp. 4983-4991
    • Luo, W.1    Sharif, T.R.2    Sharif, M.3
  • 75
    • 0038137331 scopus 로고    scopus 로고
    • Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer
    • Friess H, Zhu Z, Liard V, Shi X, Shrikhande SV, Wang L, et al. Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer. Lab Invest 2003; 83: 731-42.
    • (2003) Lab Invest , vol.83 , pp. 731-742
    • Friess, H.1    Zhu, Z.2    Liard, V.3    Shi, X.4    Shrikhande, S.V.5    Wang, L.6
  • 76
    • 23044450652 scopus 로고    scopus 로고
    • The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines
    • Munoz M, Rosso M, Perez A, Covenas R, Rosso R, Zamarriego C, et al. The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines. Neuropeptides 2005; 39: 427-32.
    • (2005) Neuropeptides , vol.39 , pp. 427-432
    • Munoz, M.1    Rosso, M.2    Perez, A.3    Covenas, R.4    Rosso, R.5    Zamarriego, C.6
  • 79
    • 65649138814 scopus 로고    scopus 로고
    • A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas
    • Akazawa T, Kwatra SG, Goldsmith LE, Richardson MD, Cox EA, Sampson JH, et al. A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas. J Neurochem 2009; 109: 1079-86.
    • (2009) J Neurochem , vol.109 , pp. 1079-1086
    • Akazawa, T.1    Kwatra, S.G.2    Goldsmith, L.E.3    Richardson, M.D.4    Cox, E.A.5    Sampson, J.H.6
  • 80
    • 27644463170 scopus 로고    scopus 로고
    • Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231
    • Bigioni M, Benzo A, Irrissuto C, Maggi CA, Goso C. Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231. Anticancer Drugs 2005; 16: 1083-9.
    • (2005) Anticancer Drugs , vol.16 , pp. 1083-1089
    • Bigioni, M.1    Benzo, A.2    Irrissuto, C.3    Maggi, C.A.4    Goso, C.5
  • 83
    • 0034698313 scopus 로고    scopus 로고
    • The role of tachykinins via NK1 receptors in progression of human gliomas
    • Palma C, Maggi CA. The role of tachykinins via NK1 receptors in progression of human gliomas. Life Sci 2000; 67: 985-1001.
    • (2000) Life Sci , vol.67 , pp. 985-1001
    • Palma, C.1    Maggi, C.A.2
  • 85
    • 34249785108 scopus 로고    scopus 로고
    • Nonclassic endogenous novel regulators of angiogenesis
    • Ribatti D, Conconi MT, Nussdorfer GG. Nonclassic endogenous novel regulators of angiogenesis. Pharmacol Rev 2007; 59: 185-205.
    • (2007) Pharmacol Rev , vol.59 , pp. 185-205
    • Ribatti, D.1    Conconi, M.T.2    Nussdorfer, G.G.3
  • 86
    • 0141649387 scopus 로고    scopus 로고
    • Bradykinin antagonists as anti-cancer agents
    • Stewart JM. Bradykinin antagonists as anti-cancer agents. Curr Pharm Des 2003; 9: 2036-42.
    • (2003) Curr Pharm Des , vol.9 , pp. 2036-2042
    • Stewart, J.M.1
  • 87
    • 0035687599 scopus 로고    scopus 로고
    • A potential role of bradykinin in angiogenesis and growth of S-180 mouse tumors
    • Ishihara K, Hayash I, Yamashina S, Majima M. A potential role of bradykinin in angiogenesis and growth of S-180 mouse tumors. Jpn J Pharmacol 2001; 87: 318-26.
    • (2001) Jpn J Pharmacol , vol.87 , pp. 318-326
    • Ishihara, K.1    Hayash, I.2    Yamashina, S.3    Majima, M.4
  • 88
    • 0027339657 scopus 로고
    • [Leu8]des-Arg9-bradykinin inhibits the angiogenic effect of bradykinin and interleukin-1 in rats
    • Hu DE, Fan TP. [Leu8]des-Arg9-bradykinin inhibits the angiogenic effect of bradykinin and interleukin-1 in rats. Br J Pharmacol 1993; 109:14-7.
    • (1993) Br J Pharmacol , vol.109 , pp. 14-17
    • Hu, D.E.1    Fan, T.P.2
  • 91
    • 0025033180 scopus 로고
    • Peritumoral brain edema. A keynote address
    • Reulen HJ, Huber P, Ito U, Groger U. Peritumoral brain edema. A keynote address. Adv Neurol 1990; 52: 307-15.
    • (1990) Adv Neurol , vol.52 , pp. 307-315
    • Reulen, H.J.1    Huber, P.2    Ito, U.3    Groger, U.4
  • 92
  • 95
    • 33845591614 scopus 로고    scopus 로고
    • Increased migration and metastatic potential of tumor cells expressing aquaporin water channels
    • Hu J, Verkman AS. Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J 2006; 20: 1892-4.
    • (2006) FASEB J , vol.20 , pp. 1892-1894
    • Hu, J.1    Verkman, A.S.2
  • 97
    • 42149104435 scopus 로고    scopus 로고
    • Inhibition of neurogenic inflammation as a novel treatment for ischemic stroke
    • Turner R, Vink R. Inhibition of neurogenic inflammation as a novel treatment for ischemic stroke. Timely Top Med Cardiovasc Dis 2007; 11: E24.
    • (2007) Timely Top Med Cardiovasc Dis , vol.11
    • Turner, R.1    Vink, R.2
  • 98
    • 1442303846 scopus 로고    scopus 로고
    • Neuropeptide release influences brain edema formation after diffuse traumatic brain injury
    • Vink R, Young A, Bennett CJ, Hu X, Connor CO, Cernak I, et al. Neuropeptide release influences brain edema formation after diffuse traumatic brain injury. Acta Neurochir Suppl 2003; 86: 257-60.
    • (2003) Acta Neurochir Suppl , vol.86 , pp. 257-260
    • Vink, R.1    Young, A.2    Bennett, C.J.3    Hu, X.4    Connor, C.O.5    Cernak, I.6
  • 100
    • 73949140286 scopus 로고    scopus 로고
    • The role of bradykinin B(1) and B(2) receptors for secondary brain damage after traumatic brain injury in mice
    • Trabold R, Eros C, Zweckberger K, Relton J, Beck H, Nussberger J, et al. The role of bradykinin B(1) and B(2) receptors for secondary brain damage after traumatic brain injury in mice. J Cereb Blood Flow Metab 2010; 30:130-9.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 130-139
    • Trabold, R.1    Eros, C.2    Zweckberger, K.3    Relton, J.4    Beck, H.5    Nussberger, J.6
  • 101
    • 69249212164 scopus 로고    scopus 로고
    • Blockade of bradykinin B2 receptor more effectively reduces postischemic blood-brain barrier disruption and cytokines release than B1 receptor inhibition
    • Su J, Cui M, Tang Y, Zhou H, Liu L, Dong Q. Blockade of bradykinin B2 receptor more effectively reduces postischemic blood-brain barrier disruption and cytokines release than B1 receptor inhibition. Biochem Biophys Res Commun 2009; 388: 205-11.
    • (2009) Biochem Biophys Res Commun , vol.388 , pp. 205-211
    • Su, J.1    Cui, M.2    Tang, Y.3    Zhou, H.4    Liu, L.5    Dong, Q.6
  • 102
    • 41149121644 scopus 로고    scopus 로고
    • Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton
    • Liu LB, Xue YX, Liu YH, Wang YB. Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton. J Neurosci Res 2008; 86: 1153-68.
    • (2008) J Neurosci Res , vol.86 , pp. 1153-1168
    • Liu, L.B.1    Xue, Y.X.2    Liu, Y.H.3    Wang, Y.B.4
  • 106
    • 0029900093 scopus 로고    scopus 로고
    • Enhanced tumor uptake of carboplatin and survival in gliomabearing rats by intracarotid infusion of bradykinin analog, RMP-7
    • Matsukado K, Inamura T, Nakano S, Fukui M, Bartus RT, Black KL. Enhanced tumor uptake of carboplatin and survival in gliomabearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 1996; 39: 125-33.
    • (1996) Neurosurgery , vol.39 , pp. 125-133
    • Matsukado, K.1    Inamura, T.2    Nakano, S.3    Fukui, M.4    Bartus, R.T.5    Black, K.L.6
  • 107
    • 32344438099 scopus 로고    scopus 로고
    • Study of correlation between expression of bradykinin B2 receptor and pathological grade in human gliomas
    • Zhao Y, Xue Y, Liu Y, Fu W, Jiang N, An P, et al. Study of correlation between expression of bradykinin B2 receptor and pathological grade in human gliomas. Br J Neurosurg 2005; 19: 322-6.
    • (2005) Br J Neurosurg , vol.19 , pp. 322-326
    • Zhao, Y.1    Xue, Y.2    Liu, Y.3    Fu, W.4    Jiang, N.5    An, P.6
  • 108
    • 0029815942 scopus 로고    scopus 로고
    • Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide
    • Nakano S, Matsukado K, Black KL. Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide. Cancer Res 1996; 56: 4027-31.
    • (1996) Cancer Res , vol.56 , pp. 4027-4031
    • Nakano, S.1    Matsukado, K.2    Black, K.L.3
  • 109
    • 54049086905 scopus 로고    scopus 로고
    • PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model
    • Black KL, Yin D, Ong JM, Hu J, Konda BM, Wang X, et al. PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model. Brain Res 2008; 1230: 290-302.
    • (2008) Brain Res , vol.1230 , pp. 290-302
    • Black, K.L.1    Yin, D.2    Ong, J.M.3    Hu, J.4    Konda, B.M.5    Wang, X.6
  • 110
    • 33947617203 scopus 로고    scopus 로고
    • Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model
    • Hu J, Yuan X, Ko MK, Yin D, Sacapano MR, Wang X, et al. Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model. Mol Cancer 2007; 6: 22.
    • (2007) Mol Cancer , vol.6 , pp. 22
    • Hu, J.1    Yuan, X.2    Ko, M.K.3    Yin, D.4    Sacapano, M.R.5    Wang, X.6
  • 112
    • 77956326618 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models
    • Hu J, Ljubimova JY, Inoue S, Konda B, Patil R, Ding H, et al. Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models. PLoS One 2010; 5: e10108.
    • (2010) PLoS One , vol.e10108 , pp. 5
    • Hu, J.1    Ljubimova, J.Y.2    Inoue, S.3    Konda, B.4    Patil, R.5    Ding, H.6
  • 116
    • 14844354089 scopus 로고    scopus 로고
    • Candidates for peptide receptor radiotherapy today and in the future
    • Reubi JC, Macke HR, Krenning EP. Candidates for peptide receptor radiotherapy today and in the future. J Nucl Med 2005; 46 (Suppl 1): 67S-75S.
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Reubi, J.C.1    Macke, H.R.2    Krenning, E.P.3
  • 117
    • 41649083838 scopus 로고    scopus 로고
    • Targeted tumor diagnosis and therapy with peptide hormones as radiopharmaceuticals
    • Khan IU, Beck-Sickinger AG. Targeted tumor diagnosis and therapy with peptide hormones as radiopharmaceuticals. Anticancer Agents Med Chem 2008; 8: 186-99.
    • (2008) Anticancer Agents Med Chem , vol.8 , pp. 186-199
    • Khan, I.U.1    Beck-Sickinger, A.G.2
  • 119
    • 78650952753 scopus 로고    scopus 로고
    • Neoadjuvant targeting of glioblastoma multiforme with radiolabeled DOTAGA-substance P-results from a phase I study
    • Cordier D, Forrer F, Kneifel S, Sailer M, Mariani L, Macke H, et al. Neoadjuvant targeting of glioblastoma multiforme with radiolabeled DOTAGA-substance P-results from a phase I study. J Neurooncol 2010; 100: 129-36.
    • (2010) J Neurooncol , vol.100 , pp. 129-136
    • Cordier, D.1    Forrer, F.2    Kneifel, S.3    Sailer, M.4    Mariani, L.5    Macke, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.