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Volumn 79, Issue 1, 2011, Pages 88-97

Role of the HefC efflux pump in helicobacter pylori cholesterol-dependent resistance to ceragenins and bile salts

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BILE SALT; CERAGENIN 11; CERAGENIN 13; CERAGENIN 54; CERAGENIN 90; CHOLESTEROL; CHOLESTERYL GLYCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEI HEFF; PROTEIN HEFC; PROTEIN HEFI; UNCLASSIFIED DRUG;

EID: 78650925895     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00974-09     Document Type: Article
Times cited : (41)

References (46)
  • 5
    • 57649181740 scopus 로고    scopus 로고
    • Effect of the efflux inhibitors 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naph-thylamide on antimicrobial susceptibility and virulence factor production in Vibrio cholerae
    • Bina, X. R., J. A. Philippart, and J. E. Bina. 2009. Effect of the efflux inhibitors 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naph- thylamide on antimicrobial susceptibility and virulence factor production in Vibrio cholerae. J. Antimicrob. Chemother. 63:103-108.
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 103-108
    • Bina, X.R.1    Philippart, J.A.2    Bina, J.E.3
  • 6
    • 48849102268 scopus 로고    scopus 로고
    • Vibrio cholerae RND family efflux systems are required for antimicrobial resistance, optimal virulence factor production, and colonization of the infant mouse small intestine
    • Bina, X. R., D. Provenzano, N. Nguyen, and J. E. Bina. 2008. Vibrio cholerae RND family efflux systems are required for antimicrobial resistance, optimal virulence factor production, and colonization of the infant mouse small intestine. Infect. Immun. 76:3595-3605.
    • (2008) Infect. Immun. , vol.76 , pp. 3595-3605
    • Bina, X.R.1    Provenzano, D.2    Nguyen, N.3    Bina, J.E.4
  • 8
    • 38349170070 scopus 로고    scopus 로고
    • Potential synergy activity of the novel ceragenin, CSA-13, against clinical isolates of Pseudomonas aeruginosa, including multidrug-resistant P. aerugi-nosa
    • Chin, J. N., R. N. Jones, H. S. Sader, P. B. Savage, and M. J. Rybak. 2008. Potential synergy activity of the novel ceragenin, CSA-13, against clinical isolates of Pseudomonas aeruginosa, including multidrug-resistant P. aerugi-nosa. J. Antimicrob. Chemother. 61:365-370.
    • (2008) J. Antimicrob. Chemother. , vol.61 , pp. 365-370
    • Chin, J.N.1    Jones, R.N.2    Sader, H.S.3    Savage, P.B.4    Rybak, M.J.5
  • 9
    • 34247140867 scopus 로고    scopus 로고
    • Antimicrobial activities of ceragenins against clinical isolates of resistant Staphylo-coccus aureus
    • Chin, J. N., M. J. Rybak, C. M. Cheung, and P. B. Savage. 2007. Antimicrobial activities of ceragenins against clinical isolates of resistant Staphylo-coccus aureus. Antimicrob. Agents Chemother. 51:1268-1273.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 1268-1273
    • Chin, J.N.1    Rybak, M.J.2    Cheung, C.M.3    Savage, P.B.4
  • 12
    • 56249146713 scopus 로고    scopus 로고
    • Ceragenins (cationic steroid compounds), a novel class of antimicrobial agents
    • Epand, R. M., R. F. Epand, and P. B. Savage. 2008. Ceragenins (cationic steroid compounds), a novel class of antimicrobial agents. Drug News Per-spect. 21:307-311.
    • (2008) Drug News Per-spect. , vol.21 , pp. 307-311
    • Epand, R.M.1    Epand, R.F.2    Savage, P.B.3
  • 13
    • 0031953727 scopus 로고    scopus 로고
    • Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase
    • Goodwin, A., D. Kersulyte, G. Sisson, S. J. Veldhuyzen van Zanten, D. E. Berg, and P. S. Hoffman. 1998. Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase. Mol. Microbiol. 28:383-393.
    • (1998) Mol. Microbiol. , vol.28 , pp. 383-393
    • Goodwin, A.1    Kersulyte, D.2    Sisson, G.3    Zanten Van Veldhuyzen, S.J.4    Berg, S.5    Hoffman, D.E.6
  • 14
    • 0029972062 scopus 로고    scopus 로고
    • The interaction of pH, bile, and Helicobacter pylori may explain duodenal ulcer
    • Han, S. W., D. G. Evans, F. A. el-Zaatari, M. F. Go, and D. Y. Graham. 1996. The interaction of pH, bile, and Helicobacter pylori may explain duodenal ulcer. Am. J. Gastroenterol. 91:1135-1137.
    • (1996) Am. J. Gastroenterol. , vol.91 , pp. 1135-1137
    • Han, S.W.1    Evans, D.G.2    El-Zaatari, F.A.3    Go, M.F.4    Graham, D.Y.5
  • 15
    • 0025868472 scopus 로고
    • Sensitivity of Helicobacter pylori to different bile salts
    • Hanninen, M. L. 1991. Sensitivity of Helicobacter pylori to different bile salts. Eur. J. Clin. Microbiol. Infect. Dis. 10:515-518.
    • (1991) Eur. J. Clin. Microbiol. Infect. Dis. , vol.10 , pp. 515-518
    • Hanninen, M.L.1
  • 17
    • 0029348972 scopus 로고
    • Lipid profiles of Helicobacter pylori and Helicobacter mustelae grown in serum-supplemented and serum-free media
    • Haque, M., Y. Hirai, K. Yokota, and K. Oguma. 1995. Lipid profiles of Helicobacter pylori and Helicobacter mustelae grown in serum-supplemented and serum-free media. Acta Medica Okayama 49:205-211.
    • (1995) Acta Medica Okayama , vol.49 , pp. 205-211
    • Haque, M.1    Hirai, Y.2    Yokota, K.3    Oguma, K.4
  • 18
    • 0029165789 scopus 로고
    • Steryl glycosides: A characteristic feature of the Helicobacter spp.?
    • Haque, M., Y. Hirai, K. Yokota, and K. Oguma. 1995. Steryl glycosides: a characteristic feature of the Helicobacter spp.? J. Bacteriol. 177:5334-5337.
    • (1995) J. Bacteriol. , vol.177 , pp. 5334-5337
    • Haque, M.1    Hirai, Y.2    Yokota, K.3    Oguma, K.4
  • 19
    • 74549121385 scopus 로고    scopus 로고
    • Helicobacter pylori lipopolysaccha-ride modification. Lewis antigen expression, and gastric colonization are cholesterol-dependent
    • Hildebrandt, E., and D. J. McGee. 2009. Helicobacter pylori lipopolysaccha-ride modification, Lewis antigen expression, and gastric colonization are cholesterol-dependent. BMC Microbiol. 9:258.
    • (2009) BMC Microbiol. , vol.9 , pp. 258
    • Hildebrandt, E.1    McGee, D.J.2
  • 20
    • 0029148371 scopus 로고
    • Unique cholesteryl glucosides in Helicobacter pylori: Composition and structural analysis
    • Hirai, Y., M. Haque, T. Yoshida, K. Yokota, T. Yasuda, and K. Oguma. 1995. Unique cholesteryl glucosides in Helicobacter pylori: composition and structural analysis. J. Bacteriol. 177:5327-5333.
    • (1995) J. Bacteriol. , vol.177 , pp. 5327-5333
    • Hirai, Y.1    Haque, M.2    Yoshida, T.3    Yokota, K.4    Yasuda, T.5    Oguma, K.6
  • 22
    • 0032706298 scopus 로고    scopus 로고
    • Antibacterial action of bile acids against Helicobacter pylori and changes in its ultrastructural morphology: Effect of unconjugated dihydroxy bile acid
    • Itoh, M., K. Wada, S. Tan, Y. Kitano, J. Kai, and I. Makino. 1999. Antibacterial action of bile acids against Helicobacter pylori and changes in its ultrastructural morphology: effect of unconjugated dihydroxy bile acid. J. Gastroenterol. 34:571-576.
    • (1999) J. Gastroenterol. , vol.34 , pp. 571-576
    • Itoh, M.1    Wada, K.2    Tan, S.3    Kitano, Y.4    Kai, J.5    Makino, I.6
  • 24
    • 3943108216 scopus 로고    scopus 로고
    • Structure and function of TolC: The bacterial exit duct for proteins and drugs
    • Koronakis, V., J. Eswaran, and C. Hughes. 2004. Structure and function of TolC: the bacterial exit duct for proteins and drugs. Annu. Rev. Biochem. 73:467-489.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 467-489
    • Koronakis, V.1    Eswaran, J.2    Hughes, C.3
  • 26
    • 33748456239 scopus 로고    scopus 로고
    • In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site
    • Langford, M. L., J. Zabaleta, A. C. Ochoa, T. L. Testerman, and D. J. McGee. 2006. In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site. Helicobacter 11:477-493.
    • (2006) Helicobacter , vol.11 , pp. 477-493
    • Langford, M.L.1    Zabaleta, J.2    Ochoa, A.C.3    Testerman, T.L.4    McGee, D.J.5
  • 27
    • 45749138417 scopus 로고    scopus 로고
    • A1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol alpha-glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth
    • Lee, H., P. Wang, H. Hoshino, Y. Ito, M. Kobayashi, J. Nakayama, P. H. Seeberger, and M. Fukuda. 2008. a1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol alpha-glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth. Glycobiology 18:549-558.
    • (2008) Glycobiology , vol.18 , pp. 549-558
    • Lee, H.1    Wang, P.2    Hoshino, H.3    Ito, Y.4    Kobayashi, M.5    Nakayama, J.6    Seeberger, P.H.7    Fukuda, M.8
  • 28
    • 70349630154 scopus 로고    scopus 로고
    • Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice
    • Leszczynska, K., A. Namiot, D. E. Fein, Q. Wen, Z. Namiot, P. B. Savage, S. Diamond, P. A. Janmey, and R. Bucki. 2009. Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice. BMC Microbiol. 9:187.
    • (2009) BMC Microbiol. , vol.9 , pp. 187
    • Leszczynska, K.1    Namiot, A.2    Fein, D.E.3    Wen, Q.4    Namiot, Z.5    Savage, P.B.6    Diamond, S.7    Janmey, P.A.8    Bucki, R.9
  • 30
    • 27144500167 scopus 로고    scopus 로고
    • Bile salts modulate expression of the CmeABC multidrug efflux pump in Campylobacter jejuni
    • DOI 10.1128/JB.187.21.7417-7424.2005
    • Lin, J., C. Cagliero, B. Guo, Y. W. Barton, M. C. Maurel, S. Payot, and Q. Zhang. 2005. Bile salts modulate expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. J. Bacteriol. 187:7417-7424. (Pubitemid 41507798)
    • (2005) Journal of Bacteriology , vol.187 , Issue.21 , pp. 7417-7424
    • Lin, J.1    Cagliero, C.2    Guo, B.3    Barton, Y.-W.4    Maurel, M.-C.5    Payot, S.6    Zhang, Q.7
  • 31
    • 58149235373 scopus 로고    scopus 로고
    • Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance
    • Liu, Z. Q., P. Y. Zheng, and P. C. Yang. 2008. Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance. World J. Gastroenterol. 14:5217-5222.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 5217-5222
    • Liu, Z.Q.1    Zheng, P.Y.2    Yang, P.C.3
  • 32
    • 0028926676 scopus 로고
    • Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli
    • Ma, D., D. N. Cook, M. Alberti, N. G. Pon, H. Nikaido, and J. E. Hearst. 1995. Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli. Mol. Microbiol. 16:45-55.
    • (1995) Mol. Microbiol. , vol.16 , pp. 45-55
    • Ma, D.1    Cook, D.N.2    Alberti, M.3    Pon, N.G.4    Nikaido, H.5    Hearst, J.E.6
  • 34
    • 0014074152 scopus 로고
    • Quantitative microanalysis of bile
    • Nakayama, F. 1967. Quantitative microanalysis of bile. J. Lab. Clin. Med. 69:594-609.
    • (1967) J. Lab. Clin. Med. , vol.69 , pp. 594-609
    • Nakayama, F.1
  • 35
    • 33846468216 scopus 로고    scopus 로고
    • Minireview: Bioinformatic study of bile responses in Campylobacterales
    • Okoli, A. S., T. Wadstrom, and G. L. Mendz. 2007. Minireview: bioinformatic study of bile responses in Campylobacterales. FEMS Immunol. Med. Microbiol. 49:101-123.
    • (2007) FEMS Immunol. Med. Microbiol. , vol.49 , pp. 101-123
    • Okoli, A.S.1    Wadstrom, T.2    Mendz, G.L.3
  • 36
    • 64649100965 scopus 로고    scopus 로고
    • Drug transport mechanism of the AcrB efflux pump
    • Pos, K. M. 2009. Drug transport mechanism of the AcrB efflux pump. Biochim. Biophys. Acta 1794:782-793.
    • (2009) Biochim. Biophys. Acta , vol.1794 , pp. 782-793
    • Pos, K.M.1
  • 37
    • 49849083969 scopus 로고    scopus 로고
    • Enhancement of the efficacy of erythromycin in multiple antibiotic-resistant gram-negative bacterial pathogens
    • Saha, S., P. B. Savage, and M. Bal. 2008. Enhancement of the efficacy of erythromycin in multiple antibiotic-resistant gram-negative bacterial pathogens. J. Appl. Microbiol. 105:822-828.
    • (2008) J. Appl. Microbiol. , vol.105 , pp. 822-828
    • Saha, S.1    Savage, P.B.2    Bal, M.3
  • 39
    • 33745597636 scopus 로고    scopus 로고
    • The novel Helicobacter pylori CznABC metal efflux pump is required for cadmium, zinc, and nickel resistance, urease modulation, and gastric colonization
    • Stahler, F. N., S. Odenbreit, R. Haas, J. Wilrich, A. H. Van Vliet, J. G. Kusters, M. Kist, and S. Bereswill. 2006. The novel Helicobacter pylori CznABC metal efflux pump is required for cadmium, zinc, and nickel resistance, urease modulation, and gastric colonization. Infect. Immun. 74:3845-3852.
    • (2006) Infect. Immun. , vol.74 , pp. 3845-3852
    • Stahler, F.N.1    Odenbreit, S.2    Haas, R.3    Wilrich, J.4    Van Vliet, A.H.5    Kusters, J.G.6    Kist, M.7    Bereswill, S.8
  • 40
    • 33646554792 scopus 로고    scopus 로고
    • Nutritional requirements and antibiotic resistance patterns of Helicobacter species in chemically defined media
    • Testerman, T. L., P. B. Conn, H. L. Mobley, and D. J. McGee. 2006. Nutritional requirements and antibiotic resistance patterns of Helicobacter species in chemically defined media. J. Clin. Microbiol. 44:1650-1658.
    • (2006) J. Clin. Microbiol. , vol.44 , pp. 1650-1658
    • Testerman, T.L.1    Conn, P.B.2    Mobley, H.L.3    McGee, D.J.4
  • 41
    • 0034764726 scopus 로고    scopus 로고
    • Helicobacter pylori growth and urease detection in the chemically defined medium Ham's F-12 nutrient mixture
    • Testerman, T. L., D. J. McGee, and H. L. Mobley. 2001. Helicobacter pylori growth and urease detection in the chemically defined medium Ham's F-12 nutrient mixture. J. Clin. Microbiol. 39:3842-3850.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 3842-3850
    • Testerman, T.L.1    McGee, D.J.2    Mobley, H.L.3
  • 43
    • 16244385589 scopus 로고    scopus 로고
    • A Helicobacter pylori TolC efflux pump confers resistance to metronidazole
    • van Amsterdam, K., A. Bart, and A. van der Ende. 2005. A Helicobacter pylori TolC efflux pump confers resistance to metronidazole. Antimicrob. Agents Chemother. 49:1477-1482.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1477-1482
    • Van Amsterdam, K.1    Bart, A.2    Ende Der A.Van3
  • 44
    • 0036889319 scopus 로고    scopus 로고
    • Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori
    • Waidner, B., K. Melchers, I. Ivanov, H. Loferer, K. W. Bensch, M. Kist, and S. Bereswill. 2002. Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori. J. Bacteriol. 184:6700-6708.
    • (2002) J. Bacteriol. , vol.184 , pp. 6700-6708
    • Waidner, B.1    Melchers, K.2    Ivanov, I.3    Loferer, H.4    Bensch, K.W.5    Kist, M.6    Bereswill, S.7
  • 45
    • 21144443008 scopus 로고    scopus 로고
    • The Helicobacter pylori CrdRS two-component regulation system (HP1364/HP1365) is required for copper-mediated induction of the copper resistance determinant CrdA
    • Waidner, B., K. Melchers, F. N. Stahler, M. Kist, and S. Bereswill. 2005. The Helicobacter pylori CrdRS two-component regulation system (HP1364/HP1365) is required for copper-mediated induction of the copper resistance determinant CrdA. J. Bacteriol. 187:4683-4688.
    • (2005) J. Bacteriol. , vol.187 , pp. 4683-4688
    • Waidner, B.1    Melchers, K.2    Stahler, F.N.3    Kist, M.4    Bereswill, S.5


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