Antimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 6, 1999, Pages 1347-1349

  Li, Chunhong ^a   Lewis, Matthew R ^b   Gilbert, Amy B ^b   Noel, Mark D ^b   Scoville, David H ^b   Allman, Glenn W ^b   Savage, Paul B ^a  

^a Brigham Young University   (United States)

^b BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CHOLIC ACID DERIVATIVE; ERYTHROMYCIN; GUANIDINE; NOVOBIOCIN; POLYMYXIN; RIFAMPICIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0032996066     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.6.1347     Document Type: Article

References (10)

1. Eliopoulos, G. M., and R. C. Moellering, Jr. 1991. Antimicrobial combinations, p. 432-492. In V. Lorian (ed.). Antibiotics in laboratory medicine. Williams and Wilkins Co., Baltimore, Md.
2. Hancock, R. E. W. 1984. Alterations in outer membrane permeability. Annu. Rev. Microbiol. 38:237-264.
3. Li, C., A. S. Peters, E. L. Meredith, G. W. Allman, and P. B. Savage. 1998. Design and synthesis of potent sensitizers of Gram-negative bacteria based on a cholic acid scaffolding. J. Am. Chem. Soc. 120:2961-2962.
4. Li, C., L. P. Budge, C. D. Driscoll, B. M. Willardson, G. W. Allman, and P. B. Savage. 1999. Incremental conversion of outer-membrane permeabilizers into potent antibiotics for Gram-negative bacteria. J. Am. Chem. Soc. 121: 931-940.
5. Matsuzaki, K., K. Sugishita, N. Fujii, and K. Miyajima. 1995. Molecular basis for membrane selectivity of an antimicrobial peptide, magainin 2. Biochemistry 34:3423-3429.
6. National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed. Approved standard M7-A4. National Committee for Clinical Laboratory Standards, Villanova, Pa.
7. National Committee for Clinical Laboratory Standards. 1997. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard M27-A. National Committee for Clinical Laboratory Standards, Villanova, Pa.
8. Vaara, M. 1992. Agents that increase the permeability of the outer membrane. Microbiol. Rev. 56:395-411.
9. Vaara, M., and T. Vaara. 1983. Sensitization of Gram-negative bacteria to antibiotics and complement by nontoxic oligopeptide. Nature 303:526-528.
10. Viljanen, P., H. Matsunaga, V. Kimura, and M. Vaara. 1991. The outer membrane permeability-increasing action of deacylpolymyxins. J. Antibiot. 44:517-523.