Structural Insights into the two sequential folding transition states of the PB1 domain of NBR1 from φ value analysis and biased molecular dynamics simulations

Biochemistry

Volumn 50, Issue 1, 2011, Pages 125-135

  Chen, Ping ^a,b   Evans, Clare Louise ^a   Hirst, Jonathan D ^a   Searle, Mark S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENT DISTRIBUTIONS; DYNAMIC STRUCTURE; FOLDED STATE; FOLDING PATHWAY; FOLDING TRANSITION STATE; HIGH ENERGY; MOLECULAR DYNAMICS SIMULATIONS; POLYPEPTIDE CHAIN; SECONDARY STRUCTURES; SOLVENT ACCESSIBILITY; STRUCTURAL HETEROGENEITY; STRUCTURAL INSIGHTS; TRANSITION STATE; VALUE ANALYSIS;

MOLECULAR DYNAMICS;

POLYPEPTIDE;

ARTICLE; MOLECULAR DYNAMICS; NBR1 GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; TUMOR GENE;

HUMANS; MOLECULAR DYNAMICS SIMULATION; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

EID: 78650924377     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1016793     Document Type: Article

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