Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding

Journal of Molecular Biology

Volumn 350, Issue 4, 2005, Pages 757-775

  White, George W N ^a   Gianni, Stefano ^b   Grossmann, J Gunter ^c   Jemth, Per ^b,d   Fersht, Alan R ^b   Daggett, Valerie ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c DARESBURY LABORATORY   (United Kingdom)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Folding intermediate; Folding mechanism; Molecular dynamics; Phi value analysis; Protein folding

Indexed keywords

MUTANT PROTEIN; PROTEIN C MYB;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; EQUILIBRIUM CONSTANT; KINETICS; MOLECULAR MODEL; POLYMERIZATION; PREDICTION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; RADIATION SCATTERING; SIMULATION;

EID: 20544462511     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.05.005     Document Type: Article

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