Novel n-terminal mutation of human apolipoprotein A-I reduces self-association and impairs LCAT activation

Journal of Lipid Research

Volumn 52, Issue 1, 2011, Pages 35-44

  Weers, Paul M M ^a   Patel, Arti B ^a   Wan, Leon C P ^a   Guigard, Emmanuel ^b   Kay, Cyril M ^b   Hafi, Anouar ^c   McPherson, Ruth ^d   Marcel, Yves L ^d   Kiss, Robert S ^c  

^a CALIFORNIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Heart disease; Lecithin:cholesterol acyltransferase; Reverse cholesterol transport; Structure

Indexed keywords

ALANINE; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; SERINE;

ADULT; ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVATION; HETEROZYGOSITY; HUMAN; HYPOALPHALIPOPROTEINEMIA; LIPID TRANSPORT; MALE; OLIGOMERIZATION; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; SOLUBILIZATION;

APOLIPOPROTEIN A-I; HUMANS; KINETICS; MALE; MIDDLE AGED; MUTATION; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PHOSPHATIDYLCHOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78650913177     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M007500     Document Type: Article

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