Interaction of Lecithin:Cholesterol Acyltransferase (LCAT)·α 2-macroglobulin complex with low density Lipoprotein Receptor-related Protein (LRP): Evidence for an α 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 33241-33248

  Krimbou, Larbi ^a   Marcil, Michel ^a   Davignon, Jean ^b   Genest Jr , Jacques ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; CHOLESTEROL; DEGRADATION; ENZYMES; PURIFICATION;

CEREBROSPINAL FLUIDS;

BIOCHEMISTRY;

ALPHA 2 MACROGLOBULIN; IODINE 125; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; METHYLAMINE; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPASE C; RECOMBINANT PROTEIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E3; IMMUNOGLOBULIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; PHOSPHATIDYLCHOLINE SPECIFIC PHOSPHOLIPASE C; PHOSPHATIDYLCHOLINE-SPECIFIC PHOSPHOLIPASE C;

ARTICLE; BINDING AFFINITY; BIOAVAILABILITY; CHOLESTEROL TRANSPORT; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; INTERNALIZATION; MALE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; TIME; BINDING SITE; CELL CULTURE; CHEMISTRY; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; KINETICS; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PROTEIN BINDING;

ALPHA-MACROGLOBULINS; APOLIPOPROTEIN E3; APOLIPOPROTEINS E; BINDING SITES; CARCINOMA, HEPATOCELLULAR; GENOTYPE; HUMANS; KINETICS; LDL-RECEPTOR RELATED PROTEIN 1; LIVER NEOPLASMS; MALE; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PHOSPHOLIPASE C; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LDL; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

EID: 0035980152     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100326200     Document Type: Article

References (37)

1. Francone, O. L., Gurakar, A., and Fielding, C. J. (1989) J. Biol. Chem. 264, 7066-7072
2. Glomset, J. A. (1968) J. Lipid Res. 9, 155-167
3. Fielding, C. J., and Feilding, P. E. (1995) J. Lipid Res. 36, 211-228
4. Tall, A. R. (1993) J. Lipid Res. 34, 1255-1274
5. Vohl, M. C., Neville, T. A., Kumarathasan, R., Braschi, S., and Sparks, D. L. (1999) Biochemistry 38, 5976-5981
6. Cheung, M. C., Wolf, A. C., Lum, K. R., Tollefson, J. H., and Albers, J. J. (1986) J. Lipid Res. 27, 1135-1144
7. Krimbou, L., Tremblay, M., Davignon, J., and Cohn, J. S. (1998) J. Lipid Res. 38, 2373-2386
8. Sottrup-Jensen, L. (1987) in The Plasma Proteins. (Putnam, F. W., ed) pp. 192-291, Vol. 5, Academic Press, Inc., Orlando, FL
9. Borth, W. (1994) Ann. N. Y. Acad. Sci. 737, 267-272
10. Starkey, P. M., and Barrett, A. J. (1977) Proteinases in Mammalian Cells and Tissues (Barrett, A. J., ed) pp. 663-696, Elsevier-North Holland, Amsterdam
11. Vlaicu, R., Rus, H. G., Niculescu, F., and Cristae, A. (1985) Atherosclerosis 55, 35-50
12. Crookston, K. P., Webb, D. J., Wolf, B. B., and Gonias, S. L. (1994) J. Biol. Chem. 269, 1533-1540
13. Du, Y., Ni, B., Glinn, M., Dodel, R. C., Bales, K. R., Zhang, Z., Hyslop, P. A., and Paul, S. M. (1997) J. Neurochem. 69, 299-305
14. Jensen, P. H., Moestrup, S. K., and Gliemann, J. (1989) FEBS Lett. 255, 275-280
15. Weeb, D. J., Atkins, T. A., Crookston, K. P., Burmester, J. K., Qian, S. W., and Gonias, S. L. (1994) J. Biol. Chem. 269, 30402-30406
16. Gonias, S. L., LaMarre, J., Crookston, K. P., Webb, D. J., Wolf, B. B., Lopes, M. B. S., Moses, H. L., and Hayes, M. A. (1994) Ann. N. Y. Acad. Sci. 737, 273-290
17. Wang, C. Y., Eshleman, J. R., Willson, J. K. V., and Markowitz, S. (1995) Cancer Res. 55, 5101-5105
18. Roberts, A., and Sporn, M. (1990) Peptide Growth Factors and Their Receptors (Sporn, M., and Roberts, A., eds) pp. 419-472, Springer-Verlag, Heidelberg, Germany
19. Moses, H., Yang, E., and Pietenpol, J. (1990) Cell 63, 245-247
20. Krimbou, L., Tremblay, M., Jacques, H., Davignon, J., and Cohn, J. S. (1998) J. Lipid Res. 39, 861-872
21. Krimbou, L., Tremblay, M., Davignon, J., and Cohn, J. S. (1997) J. Lipid Res. 38, 35-48
22. Salacinski, P. R., McLean, C., Sykes, J. E., Clement-Jones, V. V., and Lowry, P. J. (1981) Anal. Biochem. 117: 136-146
23. Bolin, J., and Jonas, A. (1994) J. Biol. Chem. 269, 7429-7434
24. Marcil, M., Boucher, B., Krimbou, L., Solymoss, B. C., Davignon, J., Frohlich, J., and Genest, J., Jr. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 1015-1024
25. Matz, C. E., and Jonas, A. (1982) J. Biol. Chem. 257, 4535-4540
26. Qu, S. J., Fan, Z., Blanco-Vaca, F., and Pownall, H. J. (1995) J. Lipid Res. 36, 967-974
27. Goldstein, J. L., Basu, S. B., and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
28. Hill, J. S., and Pritchard, P. H. (1990) Clin. Chem. 36, 1871-1874
29. Chisholm, J. W., Gebre, A. K., and Parks, J. S. (1999) J. Lipid Res. 40, 1512-1519
30. Bonelli, F. S., and Jonas, A. (1989) J. Biol. Chem. 264, 14723-14728.
31. Jin, L., Shieh, J. J., Grabbe, E., Adimmolam, S., Durbin D., and Jonas, A. (1999) Biochemistry 38, 15659-15665
32. Adimoolam, S., Jin, L., Grabbe, E., Shieh, J. J., and Jonas, A. (1998) J. Biol. Chem. 273, 32561-32567
33. McLean, J., Fielding, C. J., Drayna, D., Dieplinger, H., Baer, B., Kohr, W., Henzel, W., and Lawn, R. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 2335-2339
34. Sottrup-Jensen, L. (1989) J. Biol. Chem. 264, 11539-11542
35. Illingworth, D. R., and Glover, J. (1970) Biochim. Biophys. Acta 220, 610-613
36. Smith, K. M., Lawn, R. M., and Wilcox, J. N. (1990) J. Lipid Res. 31, 995-1004
37. Collet, X., Francone, O., Besnard, F., Fielding, C. J. (1999) Biochem. Biophys. Res. Commun. 258, 73-76