Proteolytic Degradation and Impaired Secretion of an Apolipoprotein A-I Mutant Associated with Dominantly Inherited Hypoalphalipoproteinemia

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21292-21302

  McManus, Dan C ^b   Scott, Brian R ^b   Franklin, Vivian ^b   Sparks, Daniel L ^b   Marcel, Yves L ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; ENZYMES; REDUCTION; VIRUSES;

ADENOVIRUSES;

BIOCHEMISTRY;

APOLIPOPROTEIN A1; ARGININE; COMPLEMENTARY DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEUCINE; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; 8 ((4 CHLOROPHENYL)THIO)CYCLIC 3',5' AMP; 8-((4-CHLOROPHENYL)THIO)CYCLIC-3',5'-AMP; CHOLESTEROL; CYCLIC AMP; DRUG DERIVATIVE; NUCLEOTIDE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DOMINANT INHERITANCE; ENZYME ACTIVATION; FEMALE; HETEROZYGOTE; HYPOALPHALIPOPROTEINEMIA; HYPOLIPOPROTEINEMIA; IN VITRO STUDY; IN VIVO STUDY; LIPOPROTEIN SECRETION; LIVER CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; VIRUS RECOMBINANT; AMINO ACID SUBSTITUTION; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; DRUG EFFECT; FINLAND; GENE TRANSFER; GENETIC VARIABILITY; GENETICS; HUMAN; KINETICS; MACROPHAGE; METABOLISM; MISSENSE MUTATION; MOUSE MUTANT; PHYSIOLOGY;

ADENOVIRIDAE; ANIMALIA; MURINAE;

AMINO ACID SUBSTITUTION; ANIMALS; APOLIPOPROTEIN A-I; ARGININE; CELL LINE; CHOLESTEROL; CHOLESTEROL, HDL; CYCLIC AMP; FINLAND; GENE TRANSFER TECHNIQUES; HEPATOCYTES; HUMANS; HYPOLIPOPROTEINEMIAS; KINETICS; LEUCINE; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION, MISSENSE; THIONUCLEOTIDES; VARIATION (GENETICS);

EID: 0035877766     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100463200     Document Type: Article

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