메뉴 건너뛰기




Volumn 104, Issue 1, 2011, Pages 128-137

Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling

Author keywords

4T1 cell; breast cancer; IL 1; leptin; VEGF; VEGFR2

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; STAT3 PROTEIN; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 78650908647     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6606013     Document Type: Article
Times cited : (91)

References (52)
  • 3
    • 0036375050 scopus 로고    scopus 로고
    • Interleukin-1 - A major pleiotropic cytokine in tumor-host interactions
    • Apte RN, Voronov E (2002) Interleukin-1-a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol 12: 277-290
    • (2002) Semin Cancer Biol , vol.12 , pp. 277-290
    • Apte, R.N.1    Voronov, E.2
  • 4
    • 33745918631 scopus 로고    scopus 로고
    • Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells
    • Beevers CS, Li F, Liu L, Huang S (2006) Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells. Int J Cancer 119: 757-764
    • (2006) Int J Cancer , vol.119 , pp. 757-764
    • Beevers, C.S.1    Li, F.2    Liu, L.3    Huang, S.4
  • 5
    • 0032499534 scopus 로고    scopus 로고
    • NF-kappaB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1alpha
    • Bhat-Nakshatri P, Newton TR, Goulet Jr R, Nakshatri H (1998) NF-kappaB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1alpha. Proc Natl Acad Sci USA 95: 6971-6976
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6971-6976
    • Bhat-Nakshatri, P.1    Newton, T.R.2    Goulet Jr., R.3    Nakshatri, H.4
  • 8
    • 0035933126 scopus 로고    scopus 로고
    • Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF
    • Cao R, Brakenhielm E, Wahlestedt C, Thyberg J, Cao Y (2001) Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF. Proc Natl Acad Sci USA 98: 6390-6395
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6390-6395
    • Cao, R.1    Brakenhielm, E.2    Wahlestedt, C.3    Thyberg, J.4    Cao, Y.5
  • 9
    • 70449732756 scopus 로고    scopus 로고
    • The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis
    • Carmi Y, Voronov E, Dotan S (2009) The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis. J Immunol 183: 4705-4714
    • (2009) J Immunol , vol.183 , pp. 4705-4714
    • Carmi, Y.1    Voronov, E.2    Dotan, S.3
  • 11
    • 39049176508 scopus 로고    scopus 로고
    • Insulin resistance, growth factors and cytokine levels in overweight women with breast cancer before and after chemotherapy
    • Chala E, Manes C, Iliades H, Skaragkas G, Mouratidou D, Kapantais E (2006) Insulin resistance, growth factors and cytokine levels in overweight women with breast cancer before and after chemotherapy. Hormones (Athens) 5: 137-146
    • (2006) Hormones (Athens , vol.5 , pp. 137-146
    • Chala, E.1    Manes, C.2    Iliades, H.3    Skaragkas, G.4    Mouratidou, D.5    Kapantais, E.6
  • 12
    • 70350746065 scopus 로고    scopus 로고
    • TGF-beta-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM
    • Chen H, Yang WW, Wen QT, Xu L, Chen M (2009) TGF-beta-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM. Exp Mol Pathol 87: 189-194
    • (2009) Exp Mol Pathol , vol.87 , pp. 189-194
    • Chen, H.1    Yang, W.W.2    Wen, Q.T.3    Xu, L.4    Chen, M.5
  • 13
    • 0742287956 scopus 로고    scopus 로고
    • Leptin receptor-deficient MMTV-TGF-alpha/Lepr (db) Lepr (db) female mice do not develop oncogene-induced mammary tumors
    • Cleary MP, Juneja SC, Phillips FC, Hu X, Grande JP, Maihle NJ (2004) Leptin receptor-deficient MMTV-TGF-alpha/Lepr (db) Lepr (db) female mice do not develop oncogene-induced mammary tumors. Exp Biol Med (Maywood) 229: 182-193
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 182-193
    • Cleary, M.P.1    Juneja, S.C.2    Phillips, F.C.3    Hu, X.4    Grande, J.P.5    Maihle, N.J.6
  • 16
    • 0035880693 scopus 로고    scopus 로고
    • Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma
    • Daling JR, Malone KE, Doody DR, Johnson LG, Gralow JR, Porter PL (2001) Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma. Cancer 92: 720-729
    • (2001) Cancer , vol.92 , pp. 720-729
    • Daling, J.R.1    Malone, K.E.2    Doody, D.R.3    Johnson, L.G.4    Gralow, J.R.5    Porter, P.L.6
  • 19
    • 30044434035 scopus 로고    scopus 로고
    • Intracellular signalling pathways activated by leptin
    • Frühbeck G (2006) Intracellular signalling pathways activated by leptin. Biochem J 393: 7-20
    • (2006) Biochem J , vol.393 , pp. 7-20
    • Frühbeck, G.1
  • 20
    • 73949086088 scopus 로고    scopus 로고
    • An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 30 untranslated region confers risk for hepatocellular carcinoma
    • Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S, Zhou Y, Liu H (2009) An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 30 untranslated region confers risk for hepatocellular carcinoma. Carcinogenesis 30: 2064-2069
    • (2009) Carcinogenesis , vol.30 , pp. 2064-2069
    • Gao, Y.1    He, Y.2    Ding, J.3    Wu, K.4    Hu, B.5    Liu, Y.6    Wu, Y.7    Guo, B.8    Shen, Y.9    Landi, D.10    Landi, S.11    Zhou, Y.12    Liu, H.13
  • 22
    • 0037366151 scopus 로고    scopus 로고
    • Leptin regulation of the interleukin-1 system in human endometrial cells
    • Gonzalez RR, Leary K, Petrozza JC, Leavis PC (2003) Leptin regulation of the interleukin-1 system in human endometrial cells. Mol Hum Reprod 9: 151-158
    • (2003) Mol Hum Reprod , vol.9 , pp. 151-158
    • Gonzalez, R.R.1    Leary, K.2    Petrozza, J.C.3    Leavis, P.C.4
  • 23
    • 77953704226 scopus 로고    scopus 로고
    • Leptin upregulates VEGF in breast cancer via canonic and non-canonic signaling pathways and NFkappaB/HIF-1alpha activation
    • Gonzalez-Perez RR, Xu Y, Guo S, Watters A, Zhou W, Leibovich SJ (2010) Leptin upregulates VEGF in breast cancer via canonic and non-canonic signaling pathways and NFkappaB/HIF-1alpha activation. Cell Signal 22: 1350-1362
    • Cell Signal , vol.22 , pp. 1350-1362
    • Gonzalez-Perez, R.R.1    Xu, Y.2    Guo, S.3    Watters, A.4    Zhou, W.5
  • 26
    • 3042817487 scopus 로고    scopus 로고
    • Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    • Ishikawa M, Kitayama J, Nagawa H (2004) Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 10: 4325-4331
    • (2004) Clin Cancer Res , vol.10 , pp. 4325-4331
    • Ishikawa, M.1    Kitayama, J.2    Nagawa, H.3
  • 27
    • 78650924760 scopus 로고    scopus 로고
    • Molecular mechanisms of leptin and adiponectin in breast cancer
    • Published online 4 October 2010
    • Jarde T, Perrier S, Vasson MP, Caldefie-Chezet F (2010) Molecular mechanisms of leptin and adiponectin in breast cancer. Eur J Cancer, Published online 4 October 2010
    • (2010) Eur J Cancer
    • Jarde, T.1    Perrier, S.2    Vasson, M.P.3    Caldefie-Chezet, F.4
  • 30
  • 31
    • 33845212729 scopus 로고    scopus 로고
    • Interleukin-1 and cancer progression: The emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment
    • Lewis AM, Varghese S, Xu H, Alexander HR (2006) Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med 4: 485-510
    • (2006) J Transl Med , vol.4 , pp. 485-510
    • Lewis, A.M.1    Varghese, S.2    Xu, H.3    Alexander, H.R.4
  • 34
    • 33644527562 scopus 로고    scopus 로고
    • High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels
    • Miyoshi Y, Funahashi T, Tanaka S, Taguchi T, Tamaki Y, Shimomura I, Noguchi S (2006) High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels. Int J Cancer 118: 1414-1419
    • (2006) Int J Cancer , vol.118 , pp. 1414-1419
    • Miyoshi, Y.1    Funahashi, T.2    Tanaka, S.3    Taguchi, T.4    Tamaki, Y.5    Shimomura, I.6    Noguchi, S.7
  • 35
    • 0033603461 scopus 로고    scopus 로고
    • Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells
    • Newton TR, Patel NM, Bhat-Nakshatri P, Stauss CR, Goulet Jr RJ, Nakshatri H (1999) Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells. J Biol Chem 274: 18827-18835
    • (1999) J Biol Chem , vol.274 , pp. 18827-18835
    • Newton, T.R.1    Patel, N.M.2    Bhat-Nakshatri, P.3    Stauss, C.R.4    Goulet Jr., R.J.5    Nakshatri, H.6
  • 36
    • 0037152340 scopus 로고    scopus 로고
    • Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: Reciprocal involvement of PKC-alpha and PPAR expression
    • Okumura M, Yamamoto M, Sakuma H, Kojima T, Maruyama T, Jamali M, Cooper DR, Yasuda K (2002) Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: Reciprocal involvement of PKC-alpha and PPAR expression. Biochim Biophys Acta 1592: 107-116
    • (2002) Biochim Biophys Acta , vol.1592 , pp. 107-116
    • Okumura, M.1    Yamamoto, M.2    Sakuma, H.3    Kojima, T.4    Maruyama, T.5    Jamali, M.6    Cooper, D.R.7    Yasuda, K.8
  • 40
    • 77949566512 scopus 로고    scopus 로고
    • Leptin as a potential therapeutic target for breast cancer prevention and treatment
    • Ray A, Cleary MP (2010) Leptin as a potential therapeutic target for breast cancer prevention and treatment. Expert Opin Ther Targets 14: 443-451
    • (2010) Expert Opin Ther Targets , vol.14 , pp. 443-451
    • Ray, A.1    Cleary, M.P.2
  • 41
    • 70349741579 scopus 로고    scopus 로고
    • Leptin-signaling inhibition results in efficient antitumor activity in estrogen receptor positive or negative breast cancer
    • Rene Gonzalez R, Watters A, Xu Y, Singh UP, Mann DR, Rueda BR, Penichet ML (2009) Leptin-signaling inhibition results in efficient antitumor activity in estrogen receptor positive or negative breast cancer. Breast Cancer Res 11(3): R36
    • (2009) Breast Cancer Res , vol.11 , Issue.3
    • Rene Gonzalez, R.1    Watters, A.2    Xu, Y.3    Singh, U.P.4    Mann, D.R.5    Rueda, B.R.6    Penichet, M.L.7
  • 42
    • 0035872399 scopus 로고    scopus 로고
    • Constitutive SP1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma
    • Shi Q, Le X, Abbruzzese JL, Peng Z, Qian CN, Tang H, Xiong Q, Wang B, Li XC, Xie K (2001) Constitutive SP1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. Cancer Res 61: 4143-4154
    • (2001) Cancer Res , vol.61 , pp. 4143-4154
    • Shi, Q.1    Le Abbruzzese X, J.L.2    Peng, Z.3    Qian, C.N.4    Tang, H.5    Xiong, Q.6    Wang, B.7    Li, X.C.8    Xie, K.9
  • 44
    • 34548089656 scopus 로고    scopus 로고
    • Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells
    • Streicher KL, Willmarth NE, Garcia J, Boerner JL, Dewey TG, Ethier SP (2007) Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells. Mol Cancer Res 5: 847-861
    • (2007) Mol Cancer Res , vol.5 , pp. 847-861
    • Streicher, K.L.1    Willmarth, N.E.2    Garcia, J.3    Boerner, J.L.4    Dewey, T.G.5    Ethier, S.P.6
  • 46
    • 69849103351 scopus 로고    scopus 로고
    • Effect of pro-inflammatory cytokine stimulation on human breast cancer: Implications of chemokine receptor expression in cancer metastasis
    • Valdivia-Silva JE, Franco-Barraza J, Silva AL, Pont GD, Soldevila G, Meza I, Garcia-Zepeda EA (2009) Effect of pro-inflammatory cytokine stimulation on human breast cancer: implications of chemokine receptor expression in cancer metastasis. Cancer Lett 283: 176-185
    • (2009) Cancer Lett , vol.283 , pp. 176-185
    • Valdivia-Silva, J.E.1    Franco-Barraza, J.2    Silva, A.L.3    Pont, G.D.4    Soldevila, G.5    Meza, I.6    Garcia-Zepeda, E.A.7
  • 50
    • 13644270390 scopus 로고    scopus 로고
    • SHP-2 promoting migration and metastasis of MCF-7 with loss of E-cadherin, dephosphorylation of FAK and secretion of MMP-9 induced by IL-1beta in vivo and in vitro
    • Wang FM, Liu HQ, Liu SR, Tang SP, Yang L, Feng GS (2005) SHP-2 promoting migration and metastasis of MCF-7 with loss of E-cadherin, dephosphorylation of FAK and secretion of MMP-9 induced by IL-1beta in vivo and in vitro. Breast Cancer Res Treat 89: 5-14
    • (2005) Breast Cancer Res Treat , vol.89 , pp. 5-14
    • Wang, F.M.1    Liu, H.Q.2    Liu, S.R.3    Tang, S.P.4    Yang, L.5    Feng, G.S.6
  • 51
    • 0023779436 scopus 로고
    • Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene
    • Weyman CM, Taparowsky EJ, Wolfson M, Ashendel CL (1988) Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene. Cancer Res 48: 6535-6541
    • (1988) Cancer Res , vol.48 , pp. 6535-6541
    • Weyman, C.M.1    Taparowsky, E.J.2    Wolfson, M.3    Ashendel, C.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.