Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity

FEBS Letters

Volumn 583, Issue 14, 2009, Pages 2359-2364

  Erdmann, Frank ^a   Jung, Martin ^b   Eyrisch, Susanne ^c   Lang, Sven ^b   Helms, Volkhard ^c   Wagner, Richard ^a   Zimmermann, Richard ^b  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Electrophysiological property; Endoplasmic reticulum; Lanthanum; Protein transport; Sec61 complex

Indexed keywords

CARRIER PROTEIN; LANTHANUM; POLYPEPTIDE; PROTEIN PRECURSOR; PROTEIN SEC61; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; ENDOPLASMIC RETICULUM; MAMMAL; METAL BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

ANIMALS; BINDING SITES; DOGS; ENDOPLASMIC RETICULUM; HUMANS; ION CHANNEL GATING; IONS; LANTHANUM; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN TRANSPORT;

MAMMALIA;

EID: 67650144829     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.06.032     Document Type: Article

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