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Angewandte Chemie - International Edition

Volumn 50, Issue 2, 2011, Pages 542-544

Elucidation of the α-keto-aldehyde binding mechanism: A lead structure motif for proteasome inhibition

(6) Gallastegui, Nerea a Stein, Martin a Schmidt, Boris b Kloetzel, Peter Michael c Huber, Robert d,e,f Groll, Michael a

a TECHNICAL UNIVERSITY OF MUNICH (Germany)

b Institute for Organic Chemistry and Biochemistry (Germany)

c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (Germany)

d MAX PLANCK INSTITUTE OF BIOCHEMISTRY (Germany)

e UNIVERSITY OF DUISBURG ESSEN (Germany)

f CARDIFF UNIVERSITY (United Kingdom)

Author keywords

drug discovery; peptidyl glyoxals; proteasomes; reversible inhibition; structure elucidation

Indexed keywords

DRUG DISCOVERY; PEPTIDYL GLYOXALS; PROTEASOMES; REVERSIBLE INHIBITIONS; STRUCTURE ELUCIDATION;

AMINO ACIDS; BINDING ENERGY; FUNCTIONAL GROUPS;

ALDEHYDES;

ALDEHYDE; KETONE; PEPTIDE; PROTEASOME; SCHIFF BASE;

ARTICLE; BINDING SITE; CHEMISTRY; COMPUTER SIMULATION; CYCLIZATION; DRUG ANTAGONISM; DRUG SCREENING; ENZYME ACTIVE SITE; METABOLISM; PROTEIN BINDING;

ALDEHYDES; BINDING SITES; CATALYTIC DOMAIN; COMPUTER SIMULATION; CYCLIZATION; DRUG EVALUATION, PRECLINICAL; KETONES; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; SCHIFF BASES;

EID: 78650904648 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201005488 Document Type: Article

Times cited : (24)

References (26)

1
- 78049264771
- N. Gallastegui, M. Groll, Trends Biochem. Sci. 2010, 35, 634-642.
- (2010) Trends Biochem. Sci. , vol.35 , pp. 634-642
- Gallastegui, N.¹ Groll, M.²

2
- 77949439403
- E. Genin, M. Reboud-Ravaux, J. Vidal, Curr. Top. Med. Chem. 2010, 10, 232-256.
- (2010) Curr. Top. Med. Chem. , vol.10 , pp. 232-256
- Genin, E.¹ Reboud-Ravaux, M.² Vidal, J.³

3
- 33947659939
- L. Borissenko, M. Groll, Chem. Rev. 2007, 107, 687-717.
- (2007) Chem. Rev. , vol.107 , pp. 687-717
- Borissenko, L.¹ Groll, M.²

4
- 0029042511
- J. Löwe, D. Stock, B. Jap, P. Zwickl, W. Baumeister, R. Huber, Science 1995, 268, 533-539.
- (1995) Science , vol.268 , pp. 533-539
- Löwe, J.¹ Stock, D.² Jap, B.³ Zwickl, P.⁴ Baumeister, W.⁵ Huber, R.⁶

5
- 0030897031
- M. Groll, L. Ditzel, J. Lowe, D. Stock, M. Bochtler, H. D. Bartunik, R. Huber, Nature 1997, 386, 463-471.
- (1997) Nature , vol.386 , pp. 463-471
- Groll, M.¹ Ditzel, L.² Lowe, J.³ Stock, D.⁴ Bochtler, M.⁵ Bartunik, H.D.⁶ Huber, R.⁷

6
- 0001283831
- J. Adams, R. Stein, Annu. Rep. Med. Chem. 1996, 31, 279-288.
- (1996) Annu. Rep. Med. Chem. , vol.31 , pp. 279-288
- Adams, J.¹ Stein, R.²

7
- 0032539702
- J. Adams, M. Behnke, S. Chen, A. A. Cruickshank, L. R. Dick, L. Grenier, J. M. Klunder, Y. T. Ma, L. Plamondon, R. L. Stein, Bioorg. Med. Chem. Lett. 1998, 8, 333-338.
- (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 333-338
- Adams, J.¹ Behnke, M.² Chen, S.³ Cruickshank, A.A.⁴ Dick, L.R.⁵ Grenier, L.⁶ Klunder, J.M.⁷ Ma, Y.T.⁸ Plamondon, L.⁹ Stein, R.L.¹⁰

8
- 20444433230
- P. G. Richardson, et-al., N. Engl. J. Med. 2005, 352, 2487-2498.
- (2005) N. Engl. J. Med. , vol.352 , pp. 2487-2498
- Richardson, P.G.¹

9
- 52649114697
- A. A. Argyriou, G. Iconomou, H. P. Kalofonos, Blood 2008, 112, 1593-1599.
- (2008) Blood , vol.112 , pp. 1593-1599
- Argyriou, A.A.¹ Iconomou, G.² Kalofonos, H.P.³

10
- 34447116376
- S. D. Demo, C. J. Kirk, M. A. Aujay, T. J. Buchholz, M. Dajee, M. N. Ho, J. Jiang, G. J. Laidig, E. R. Lewis, F. Parlati, K. D. Shenk, M. S. Smyth, C. M. Sun, M. K. Vallone, T. M. Woo, C. J. Molineaux, M. K. Bennett, Cancer Res. 2007, 67, 6383-6391.
- (2007) Cancer Res. , vol.67 , pp. 6383-6391
- Demo, S.D.¹ Kirk, C.J.² Aujay, M.A.³ Buchholz, T.J.⁴ Dajee, M.⁵ Ho, M.N.⁶ Jiang, J.⁷ Laidig, G.J.⁸ Lewis, E.R.⁹ Parlati, F.¹⁰ Shenk, K.D.¹¹ Smyth, M.S.¹² Sun, C.M.¹³ Vallone, M.K.¹⁴ Woo, T.M.¹⁵ Molineaux, C.J.¹⁶ Bennett, M.K.¹⁷

11
- 1542292775
- R. H. Feling, G. O. Buchanan, T. J. Mincer, C. A. Kauffman, P. R. Jensen, W. Fenical, Angew. Chem. 2003, 115, 369-371
- (2003) Angew. Chem. , vol.115 , pp. 369-371
- Feling, R.H.¹ Buchanan, G.O.² Mincer, T.J.³ Kauffman, C.A.⁴ Jensen, P.R.⁵ Fenical, W.⁶

12
- 0037455147
- Angew. Chem. Int. Ed. 2003, 42, 355-357.
- (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 355-357

13
- 33646137808
- M. Groll, R. Huber, B. C. Potts, J. Am. Chem. Soc. 2006, 128, 5136-5141.
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 5136-5141
- Groll, M.¹ Huber, R.² Potts, B.C.³

14
- 78650888072
- F. Parlati, S. J. Lee, M. Aujay, E. Suzuki, K. Levitsky, J. B. Lorens, D. R. Micklem, P. Ruurs, C. Sylvain, Y. Lu, K. D. Shenk, M. K. Bennett, Blood 2009, 114, 343947.
- (2009) Blood , vol.114 , pp. 343947
- Parlati, F.¹ Lee, S.J.² Aujay, M.³ Suzuki, E.⁴ Levitsky, K.⁵ Lorens, J.B.⁶ Micklem, D.R.⁷ Ruurs, P.⁸ Sylvain, C.⁹ Lu, Y.¹⁰ Shenk, K.D.¹¹ Bennett, M.K.¹²

15
- 0027050714
- M. Hanada, K. Sugawara, K. Kaneta, S. Toda, Y. Nishiyama, K. Tomita, H. Yamamoto, M. Konishi, T. Oki, J. Antibiot. 1992, 45, 1746-1752.
- (1992) J. Antibiot. , vol.45 , pp. 1746-1752
- Hanada, M.¹ Sugawara, K.² Kaneta, K.³ Toda, S.⁴ Nishiyama, Y.⁵ Tomita, K.⁶ Yamamoto, H.⁷ Konishi, M.⁸ Oki, T.⁹

16
- 0033621047
- L. Meng, R. Mohan, B. H. Kwok, M. Elofsson, N. Sin, C. M. Crews, Proc. Natl. Acad. Sci. USA 1999, 96, 10403-14408.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10403-14408
- Meng, L.¹ Mohan, R.² Kwok, B.H.³ Elofsson, M.⁴ Sin, N.⁵ Crews, C.M.⁶

17
- 0343262654
- M. Groll, K. B. Kim, N. Kairies, R. Huber, C. M. Crews, J. Am. Chem. Soc. 2000, 122, 1237-1238.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 1237-1238
- Groll, M.¹ Kim, K.B.² Kairies, N.³ Huber, R.⁴ Crews, C.M.⁵

18
- 0032539571
- J. F. Lynas, P. Harriott, A. Healy, M. A. McKervey, B. Walker, Bioorg. Med. Chem. Lett. 1998, 8, 373-378.
- (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 373-378
- Lynas, J.F.¹ Harriott, P.² Healy, A.³ McKervey, M.A.⁴ Walker, B.⁵

19
- 33745728140
- L. J. Crawford, B. Walker, H. Ovaa, D. Chauhan, K. C. Anderson, T. C. Morris, A. E. Irvine, Cancer Res. 2006, 66, 6379-6386.
- (2006) Cancer Res. , vol.66 , pp. 6379-6386
- Crawford, L.J.¹ Walker, B.² Ovaa, H.³ Chauhan, D.⁴ Anderson, K.C.⁵ Morris, T.C.⁶ Irvine, A.E.⁷

20
- 61449206184
- M. Groll, R. Huber, L. Moroder, J. Pept. Sci. 2009, 15, 58-66.
- (2009) J. Pept. Sci. , vol.15 , pp. 58-66
- Groll, M.¹ Huber, R.² Moroder, L.³

21
- 0027302689
- B. Walker, N. McCarthy, A. Healy, T. Ye, M. A. McKervey, Biochem. J. 1993, 293, 321-323.
- (1993) Biochem. J. , vol.293 , pp. 321-323
- Walker, B.¹ McCarthy, N.² Healy, A.³ Ye, T.⁴ McKervey, M.A.⁵

22
- 17444398051
- A. Djurdjevic-Pahl, C. Hewage, J. P. Malthouse, Biochim. Biophys. Acta Proteins Proteomics 2005, 1749, 33-41.
- (2005) Biochim. Biophys. Acta Proteins Proteomics , vol.1749 , pp. 33-41
- Djurdjevic-Pahl, A.¹ Hewage, C.² Malthouse, J.P.³

23
- 75149157969
- E. Sanchez, M. Li, J. A. Steinberg, C. Wang, J. Shen, B. Bonavida, Z. W. Li, H. Chen, J. R. Berenson, Br. J. Haematol. 2010, 148, 569-581.
- (2010) Br. J. Haematol. , vol.148 , pp. 569-581
- Sanchez, E.¹ Li, M.² Steinberg, J.A.³ Wang, C.⁴ Shen, J.⁵ Bonavida, B.⁶ Li, Z.W.⁷ Chen, H.⁸ Berenson, J.R.⁹

24
- 39549106705
- S. Meiners, A. Ludwig, V. Stangl, K. Stangl, Med. Res. Rev. 2008, 28, 309-327.
- (2008) Med. Res. Rev. , vol.28 , pp. 309-327
- Meiners, S.¹ Ludwig, A.² Stangl, V.³ Stangl, K.⁴

25
- 67650388103
- T. Muchamuel, M. Basler, M. A. Aujay, E. Suzuki, K. W. Kalim, C. Lauer, C. Sylvain, E. R. Ring, J. Shields, J. Jiang, P. Shwonek, F. Parlati, S. D. Demo, M. K. Bennett, C. J. Kirk, M. Groettrup, Nat. Med. 2009, 15, 781-787.
- (2009) Nat. Med. , vol.15 , pp. 781-787
- Muchamuel, T.¹ Basler, M.² Aujay, M.A.³ Suzuki, E.⁴ Kalim, K.W.⁵ Lauer, C.⁶ Sylvain, C.⁷ Ring, E.R.⁸ Shields, J.⁹ Jiang, J.¹⁰ Shwonek, P.¹¹ Parlati, F.¹² Demo, S.D.¹³ Bennett, M.K.¹⁴ Kirk, C.J.¹⁵ Groettrup, M.¹⁶

26
- 34547858920
- L. Borissenko, M. Groll, Biol. Chem. 2007, 388, 947-955.
- (2007) Biol. Chem. , vol.388 , pp. 947-955
- Borissenko, L.¹ Groll, M.²

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