Crystal structure of epoxomicin:20S proteasome reveals a molecular basis for selectivity of α',β'-epoxyketone proteasome inhibitors [12]

Journal of the American Chemical Society

Volumn 122, Issue 6, 2000, Pages 1237-1238

  Groll, Michael ^a   Kim, Kyung Bo ^b   Kairies, Norman ^a   Huber, Robert ^a   Crews, Craig M ^b,c  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b YALE UNIVERSITY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPOXIDE; EPOXOMICIN; KETONE DERIVATIVE; MORPHOLINE DERIVATIVE; PROTEASOME; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG;

COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG STRUCTURE; LETTER; NONHUMAN; SACCHAROMYCES CEREVISIAE; STRUCTURE ANALYSIS;

EID: 0343262654     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja993588m     Document Type: Letter

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