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Volumn 38, Issue 6, 2010, Pages 1885-1892

Glucose transporter-1 as a new therapeutic target in laryngeal carcinoma

Author keywords

Glucose transporter 1 (glut 1); Laryngeal carcinoma; Targeted treatment

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTISENSE OLIGODEOXYNUCLEOTIDE; APIGENIN; CISPLATIN; DEOXYGLUCOSE; DOXORUBICIN; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 78650836005     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800601     Document Type: Article
Times cited : (45)

References (82)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O: On the origin of cancer cells. Science 1956; 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 2
    • 64749090748 scopus 로고    scopus 로고
    • Hypothesis: Using the Warburg effect against cancer by reducing glucose and providing lactate
    • Nijsten MW, van Dam GM: Hypothesis: using the Warburg effect against cancer by reducing glucose and providing lactate. Med Hypotheses 2009; 73: 48-51.
    • (2009) Med Hypotheses , vol.73 , pp. 48-51
    • Nijsten, M.W.1    van Dam, G.M.2
  • 3
    • 70749115376 scopus 로고    scopus 로고
    • Expression of metabolically targeted biomarkers in endometrial carcinoma
    • Wahl H, Daudi S, Kshirsagar M, et al: Expression of metabolically targeted biomarkers in endometrial carcinoma. Gynecol Oncol 2010; 116: 21-27.
    • (2010) Gynecol Oncol , vol.116 , pp. 21-27
    • Wahl, H.1    Daudi, S.2    Kshirsagar, M.3
  • 4
    • 48249120859 scopus 로고    scopus 로고
    • Regulation of the Warburg effect in early- passage breast cancer cells
    • Robey IF, Stephen RM, Brown KS, et al: Regulation of the Warburg effect in early- passage breast cancer cells. Neoplasia 2008; 10: 745-756.
    • (2008) Neoplasia , vol.10 , pp. 745-756
    • Robey, I.F.1    Stephen, R.M.2    Brown, K.S.3
  • 5
    • 43049109160 scopus 로고    scopus 로고
    • Aerobic glycolysis in cancers: Implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia
    • Busk M, Horsman MR, Kristjansen PE, et al: Aerobic glycolysis in cancers: implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia. Int J Cancer 2008; 122: 2726-2734.
    • (2008) Int J Cancer , vol.122 , pp. 2726-2734
    • Busk, M.1    Horsman, M.R.2    Kristjansen, P.E.3
  • 6
    • 35448940364 scopus 로고    scopus 로고
    • Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis?
    • Gillies RJ, Gatenby RA: Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? J Bioenerg Biomembr 2007; 39: 251-257.
    • (2007) J Bioenerg Biomembr , vol.39 , pp. 251-257
    • Gillies, R.J.1    Gatenby, R.A.2
  • 7
    • 58549089701 scopus 로고    scopus 로고
    • Clinical significance of FDG single-photon emission computed tomography: Computed tomography in the diagnosis of head and neck cancers and study of its mechanism
    • Li LF, Zhou SH, Zhao K, et al: Clinical significance of FDG single-photon emission computed tomography: computed tomography in the diagnosis of head and neck cancers and study of its mechanism. Cancer Biother Radiopharm 2008; 23: 701-714.
    • (2008) Cancer Biother Radiopharm , vol.23 , pp. 701-714
    • Li, L.F.1    Zhou, S.H.2    Zhao, K.3
  • 8
    • 1642553331 scopus 로고    scopus 로고
    • Expression of Glut-1 and Glut-3 in untreated oral squamous cellcarcinoma compared with FDG accumulation in a PET study
    • Tian M, Zhang H, Nakasone Y, et al: Expression of Glut-1 and Glut-3 in untreated oral squamous cellcarcinoma compared with FDG accumulation in a PET study. Eur J Nucl Med Mol Imaging 2004; 31: 5-12.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 5-12
    • Tian, M.1    Zhang, H.2    Nakasone, Y.3
  • 9
    • 33845932831 scopus 로고    scopus 로고
    • Biological correlates of FDG uptake in non-small cell lung cancer
    • de Geus-Oei LF, van Krieken JH, Aliredjo RP, et al:Biological correlates of FDG uptake in non-small cell lung cancer. Lung Cancer 2007; 55: 79-87.
    • (2007) Lung Cancer , vol.55 , pp. 79-87
    • de Geus-Oei, L.F.1    van Krieken, J.H.2    Aliredjo, R.P.3
  • 10
    • 9944262005 scopus 로고    scopus 로고
    • Expression of GLUT-1 glucose transfer, cellular proliferation activity and grade of tumor correlate with [F-18]-fluorodeoxyglucose uptake by positron emission tomography in epithelial tumors of the ovary
    • Kurokawa T, Yoshida Y, Kawahara K, et al: Expression of GLUT-1 glucose transfer, cellular proliferation activity and grade of tumor correlate with [F-18]-fluorodeoxyglucose uptake by positron emission tomography in epithelial tumors of the ovary. Int J Cancer 2004; 109: 926-932.
    • (2004) Int J Cancer , vol.109 , pp. 926-932
    • Kurokawa, T.1    Yoshida, Y.2    Kawahara, K.3
  • 11
    • 1842503945 scopus 로고    scopus 로고
    • 18F-FDG uptake in squamous cell carcinoma of the cervix is correlated with glucose transporter 1 expression
    • 18F-FDG uptake in squamous cell carcinoma of the cervix is correlated with glucose transporter 1 expression. J Nucl Med 2004; 45: 22-29.
    • (2004) J Nucl Med , vol.45 , pp. 22-29
    • Yen, T.C.1    See, L.C.2    Lai, C.H.3
  • 14
    • 0030884884 scopus 로고    scopus 로고
    • Expression of glucose transporters in human pancreatic tumors compared with increased FDG accumulation in PET study
    • Higashi T, Tamaki N, Honda T, et al: Expression of glucose transporters in human pancreatic tumors compared with increased FDG accumulation in PET study. J Nucl Med 1997; 38: 1337-1344.
    • (1997) J Nucl Med , vol.38 , pp. 1337-1344
    • Higashi, T.1    Tamaki, N.2    Honda, T.3
  • 15
    • 0030160492 scopus 로고    scopus 로고
    • Intratumoral distribution of tritiated-FDG in breast carcinoma: 1890 correlation between Glut-1 expression and FDG uptake
    • Brown RS, Leung JY, Fisher SJ, et al: Intratumoral distribution of tritiated-FDG in breast carcinoma: 1890 correlation between Glut-1 expression and FDG uptake. J Nucl Med 1996; 37: 1042-1047.
    • (1996) J Nucl Med , vol.37 , pp. 1042-1047
    • Brown, R.S.1    Leung, J.Y.2    Fisher, S.J.3
  • 16
    • 0037267005 scopus 로고    scopus 로고
    • Glucose transporters (GLUT and SGLT): Expanded families of sugar transport proteins
    • Wood IS, Trayhurn P: Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Br J Nutr 2003; 89: 3-9.
    • (2003) Br J Nutr , vol.89 , pp. 3-9
    • Wood, I.S.1    Trayhurn, P.2
  • 17
    • 0033826602 scopus 로고    scopus 로고
    • Glucose transporters and transport kinetics in retinoic acid-differentiated T47D human breast cancer cells
    • Rivenzon-Segal D, Rushkin E, Polak-Charcon S, et al: Glucose transporters and transport kinetics in retinoic acid-differentiated T47D human breast cancer cells. Am J Physiol Endocrinol Metab 2000; 279: E508-E519.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Rivenzon-Segal, D.1    Rushkin, E.2    Polak-Charcon, S.3
  • 18
    • 75349106751 scopus 로고    scopus 로고
    • GLUT1 as a therapeutic target in hepatocellular carcinoma
    • Amann T, Hellerbrand C: GLUT1 as a therapeutic target in hepatocellular carcinoma. Expert Opin Ther Targets 2009; 13: 1411-1427.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1411-1427
    • Amann, T.1    Hellerbrand, C.2
  • 19
    • 0026607990 scopus 로고
    • Mammalian facilitative glucose transporter family: Structure and molecular regulation
    • Pessin JE, Bell GI: Mammalian facilitative glucose transporter family: structure and molecular regulation. Annu Rev Physiol 1992; 54: 911-930.
    • (1992) Annu Rev Physiol , vol.54 , pp. 911-930
    • Pessin, J.E.1    Bell, G.I.2
  • 20
    • 0036321118 scopus 로고    scopus 로고
    • A reassessment of bone scintigraphy and commonly tested pretreatment biochemical parameters in newly diagnosed osteosarcoma
    • Stokkel MP, Linthorst MF, Borm JJ, et al: A reassessment of bone scintigraphy and commonly tested pretreatment biochemical parameters in newly diagnosed osteosarcoma. J Cancer Res Clin Oncol 2002; 128: 393-399.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 393-399
    • Stokkel, M.P.1    Linthorst, M.F.2    Borm, J.J.3
  • 21
    • 0034733953 scopus 로고    scopus 로고
    • Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth
    • Noguchi Y, Saito A, Miyagi Y, et al: Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth. Cancer Lett 2000; 154: 175-182.
    • (2000) Cancer Lett , vol.154 , pp. 175-182
    • Noguchi, Y.1    Saito, A.2    Miyagi, Y.3
  • 22
    • 0035424571 scopus 로고    scopus 로고
    • Expression of glucose transporter-1 in human gastric carcinoma: Association with tumor aggressiveness, metastasis, and patient survival
    • Kawamura T, Kusakabe T, Sugino T, et al: Expression of glucose transporter-1 in human gastric carcinoma: association with tumor aggressiveness, metastasis, and patient survival. Cancer 2001; 92: 634-641.
    • (2001) Cancer , vol.92 , pp. 634-641
    • Kawamura, T.1    Kusakabe, T.2    Sugino, T.3
  • 23
    • 0036171903 scopus 로고    scopus 로고
    • 18F-FDG PET, and hexokinase-II and glucose transporter-1 expression in pancreatic cancer
    • 18F-FDG PET, and hexokinase-II and glucose transporter-1 expression in pancreatic cancer. J Nucl Med 2002; 43: 173-180.
    • (2002) J Nucl Med , vol.43 , pp. 173-180
    • Higashi, T.1    Saga, T.2    Nakamoto, Y.3
  • 25
    • 65349095566 scopus 로고    scopus 로고
    • GLUT1 expression is increased in hepato cellular carcinoma and promotes tumori genesis
    • Amann T, Maegdefrau U, Hartmann A, et al: GLUT1 expression is increased in hepato cellular carcinoma and promotes tumori genesis. Am J Pathol 2009; 174: 1544-1552.
    • (2009) Am J Pathol , vol.174 , pp. 1544-1552
    • Amann, T.1    Maegdefrau, U.2    Hartmann, A.3
  • 26
    • 77749283836 scopus 로고    scopus 로고
    • Glucose transporter protein 1 expression in mucoepidermoid carcinoma of salivary gland: Correlation with grade of malignancy
    • Demasi AP, Costa AF, Altemani A, et al: Glucose transporter protein 1 expression in mucoepidermoid carcinoma of salivary gland: correlation with grade of malignancy. Int J Exp Pathol 2010; 91: 107-113.
    • (2010) Int J Exp Pathol , vol.91 , pp. 107-113
    • Demasi, A.P.1    Costa, A.F.2    Altemani, A.3
  • 28
    • 52949097303 scopus 로고    scopus 로고
    • Immuno- histochemical expression of the glucose transporters Glut-1 and Glut-3 in human malignant melanomas and benign melanocytic lesions
    • Parente P, Coli A, Massi G, et al: Immuno- histochemical expression of the glucose transporters Glut-1 and Glut-3 in human malignant melanomas and benign melanocytic lesions. J Exp Clin Cancer Res 2008; 27: 34.
    • (2008) J Exp Clin Cancer Res , vol.27 , pp. 34
    • Parente, P.1    Coli, A.2    Massi, G.3
  • 29
    • 50649099452 scopus 로고    scopus 로고
    • GLUT-1 expression in mesenchymal tumors: An immunohistochemical study of 247 soft tissue and bone neoplasms
    • Ahrens WA, Ridenour RV 3rd, Caron BL, et al: GLUT-1 expression in mesenchymal tumors: an immunohistochemical study of 247 soft tissue and bone neoplasms. Hum Pathol 2008; 39: 1519-1526.
    • (2008) Hum Pathol , vol.39 , pp. 1519-1526
    • Ahrens, W.A.1    Ridenour III., R.V.2    Caron, B.L.3
  • 30
    • 38749108156 scopus 로고    scopus 로고
    • Prognostic implications of glucose transporter protein-1 (Glut-1) overexpression in bone and soft-tissue sarcomas
    • Endo M, Tateishi U, Seki K, et al: Prognostic implications of glucose transporter protein-1 (Glut-1) overexpression in bone and soft-tissue sarcomas. Jpn J Clin Oncol 2007; 37: 955-960.
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 955-960
    • Endo, M.1    Tateishi, U.2    Seki, K.3
  • 31
    • 59249093261 scopus 로고    scopus 로고
    • Expression of Glut-1 is a prognostic marker for oral squamous cell carcinoma patients
    • Eckert AW, Lautner MH, Taubert H, et al: Expression of Glut-1 is a prognostic marker for oral squamous cell carcinoma patients. Oncol Rep 2008; 20: 1381-1385.
    • (2008) Oncol Rep , vol.20 , pp. 1381-1385
    • Eckert, A.W.1    Lautner, M.H.2    Taubert, H.3
  • 32
    • 70350627678 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2, glucose transporter-1 and angiogenesis in gallbladder carcinomas and their impact on prognosis
    • Legan M, Luzar B, Marolt VF: Expression of cyclooxygenase-2, glucose transporter-1 and angiogenesis in gallbladder carcinomas and their impact on prognosis. Scand J Gastroenterol 2009; 44: 1101-1108.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 1101-1108
    • Legan, M.1    Luzar, B.2    Marolt, V.F.3
  • 33
    • 42649112735 scopus 로고    scopus 로고
    • Expression of glucose transporter-1 and -3 in the head and neck carcinoma-the correlation of the expression with the biological behaviors
    • Zhou S, Wang S, Wu Q, et al: Expression of glucose transporter-1 and -3 in the head and neck carcinoma-the correlation of the expression with the biological behaviors. ORL J Otorhinolaryngol Relat Spec 2008; 70: 189-194.
    • (2008) ORL J Otorhinolaryngol Relat Spec , vol.70 , pp. 189-194
    • Zhou, S.1    Wang, S.2    Wu, Q.3
  • 34
    • 62749159925 scopus 로고    scopus 로고
    • Radiotherapy in larynx squamous cell carcinoma is not associated with an increased diagnosis of second primary tumours
    • Farhadieh RD, Rees CG, Yang JL, et al: Radiotherapy in larynx squamous cell carcinoma is not associated with an increased diagnosis of second primary tumours. Clin Oncol (R Coll Radiol) 2009; 21: 315-319.
    • (2009) Clin Oncol (R Coll Radiol) , vol.21 , pp. 315-319
    • Farhadieh, R.D.1    Rees, C.G.2    Yang, J.L.3
  • 35
    • 49549103347 scopus 로고    scopus 로고
    • Overexpression of intrinsic hypoxia markers HIF1α and CA-IX predict for local recurrence in stage T1-T2 glottic laryngeal carcinoma treated with radiotherapy
    • Schrijvers ML, van der Laan BF, de Bock GH, et al: Overexpression of intrinsic hypoxia markers HIF1α and CA-IX predict for local recurrence in stage T1-T2 glottic laryngeal carcinoma treated with radiotherapy. Int J Radiat Oncol Biol Phys 2008; 72: 161-169.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , pp. 161-169
    • Schrijvers, M.L.1    van der Laan, B.F.2    de Bock, G.H.3
  • 36
    • 77951898974 scopus 로고    scopus 로고
    • Cigarette smoking and progression of laryngeal lesions
    • Cikojević D, Glunić I, Klancnik M: Cigarette smoking and progression of laryngeal lesions. Coll Antropol 2010; 34(suppl 1): 45-48.
    • (2010) Coll Antropol , vol.34 , Issue.SUPPL. 1 , pp. 45-48
    • Cikojević, D.1    Glunić, I.2    Klancnik, M.3
  • 37
    • 26844433952 scopus 로고    scopus 로고
    • Long-term survival rates of laryngeal cancer patients treated by radiation and surgery, radiation alone, and surgery alone: Studied by lognormal and Kaplan-Meier survival methods
    • Tai P, Yu E, Shiels R, et al: Long-term survival rates of laryngeal cancer patients treated by radiation and surgery, radiation alone, and surgery alone: studied by lognormal and Kaplan-Meier survival methods. BMC Cancer 2005; 5: 13.
    • (2005) BMC Cancer , vol.5 , pp. 13
    • Tai, P.1    Yu, E.2    Shiels, R.3
  • 38
    • 77950502090 scopus 로고    scopus 로고
    • Comparison of different treatment modalities in advanced laryngeal hypopharyngeal squamous cell carcinoma
    • Ghaffar S, Ikram M, Imam SZ, et al: Comparison of different treatment modalities in advanced laryngeal hypopharyngeal squamous cell carcinoma. J Coll Physicians Surg Pak 2010; 20: 171-174.
    • (2010) J Coll Physicians Surg Pak , vol.20 , pp. 171-174
    • Ghaffar, S.1    Ikram, M.2    Imam, S.Z.3
  • 39
    • 70450208193 scopus 로고    scopus 로고
    • Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx: A follow-up study
    • Varghese BT, Sebastian P, Mathew A: Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx: a follow-up study. Acta Otolaryngol 2009; 129: 1480-1485.
    • (2009) Acta Otolaryngol , vol.129 , pp. 1480-1485
    • Varghese, B.T.1    Sebastian, P.2    Mathew, A.3
  • 40
    • 70349687309 scopus 로고    scopus 로고
    • Clinical outcomes of total laryngectomy for laryngeal carcinoma
    • Bajaj Y, Shayah A, Sethi N, et al: Clinical outcomes of total laryngectomy for laryngeal carcinoma. Kathmandu Univ Med J (KUMJ) 2009; 7: 258-262.
    • (2009) Kathmandu Univ Med J (KUMJ) , vol.7 , pp. 258-262
    • Bajaj, Y.1    Shayah, A.2    Sethi, N.3
  • 42
    • 77449154106 scopus 로고    scopus 로고
    • Outcome of conservation surgery for laryngeal carcinoma: An 8-year trial
    • Tuna B, Katilmiş H, Oztürkcan S, et al: Outcome of conservation surgery for laryngeal carcinoma: an 8-year trial. Eur Arch Otorhinolaryngol 2009; 266: 1681-1686.
    • (2009) Eur Arch Otorhinolaryngol , vol.266 , pp. 1681-1686
    • Tuna, B.1    Katilmiş, H.2    Oztürkcan, S.3
  • 44
    • 0037100056 scopus 로고    scopus 로고
    • Supraglottic carcinoma: Patterns of failure and salvage treatment after curatively intended radiotherapy in 410 consecutive patients
    • Johansen LV, Grau C, Overgaard J: Supraglottic carcinoma: patterns of failure and salvage treatment after curatively intended radiotherapy in 410 consecutive patients. Int J Radiat Oncol Biol Phys 2002; 53: 948-958.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 948-958
    • Johansen, L.V.1    Grau, C.2    Overgaard, J.3
  • 45
    • 22044454884 scopus 로고    scopus 로고
    • Bcl-2 expression predicts radiotherapy failure in laryngeal cancer
    • Nix P, Cawkwell L, Patmore H, et al: Bcl-2 expression predicts radiotherapy failure in laryngeal cancer. Br J Cancer 2005; 92: 2185-2189.
    • (2005) Br J Cancer , vol.92 , pp. 2185-2189
    • Nix, P.1    Cawkwell, L.2    Patmore, H.3
  • 46
    • 38049080606 scopus 로고    scopus 로고
    • Rationale for adjuvant fatty acid therapy to prevent radiotherapy failure and tumor recurrence during early laryngeal squamous cell carcinoma
    • Louw L, Claassen J: Rationale for adjuvant fatty acid therapy to prevent radiotherapy failure and tumor recurrence during early laryngeal squamous cell carcinoma. Prostaglandins Leukot Essent Fatty Acids 2008; 78: 21-26.
    • (2008) Prostaglandins Leukot Essent Fatty Acids , vol.78 , pp. 21-26
    • Louw, L.1    Claassen, J.2
  • 47
    • 12544256565 scopus 로고    scopus 로고
    • Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
    • Xu RH, Pelicano H, Zhou Y, et al: Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res 2005; 65: 613-621.
    • (2005) Cancer Res , vol.65 , pp. 613-621
    • Xu, R.H.1    Pelicano, H.2    Zhou, Y.3
  • 48
    • 72449129516 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and glucose uptake in human laryngeal carcinoma cells by antisense oligonucleotides against glucose transporter-1
    • Zhou SH, Fan J, Chen XM, et al: Inhibition of cell proliferation and glucose uptake in human laryngeal carcinoma cells by antisense oligonucleotides against glucose transporter-1. Head Neck 2009; 31: 1624-1633.
    • (2009) Head Neck , vol.31 , pp. 1624-1633
    • Zhou, S.H.1    Fan, J.2    Chen, X.M.3
  • 49
    • 26844468059 scopus 로고    scopus 로고
    • The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy
    • De Schutter H, Landuyt W, Verbeken E, et al: The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy. BMC Cancer 2005; 5: 42.
    • (2005) BMC Cancer , vol.5 , pp. 42
    • De Schutter, H.1    Landuyt, W.2    Verbeken, E.3
  • 50
    • 0034665509 scopus 로고    scopus 로고
    • Inhibition of P- glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA
    • Chan JY, Chu AC, Fung KP: Inhibition of P- glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA. Life Sci 2000; 67: 2117-2124.
    • (2000) Life Sci , vol.67 , pp. 2117-2124
    • Chan, J.Y.1    Chu, A.C.2    Fung, K.P.3
  • 51
    • 0036000133 scopus 로고    scopus 로고
    • Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 cells
    • Chen CP, Li XX, Zhang LR, et al: Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 cells. Bioconjug Chem 2002; 13: 525-529.
    • (2002) Bioconjug Chem , vol.13 , pp. 525-529
    • Chen, C.P.1    Li, X.X.2    Zhang, L.R.3
  • 52
    • 0037125388 scopus 로고    scopus 로고
    • Coexpression of glucose transporter 1 and matrix metallo-proteinase-2 in human cancers
    • Ito S, Fukusato T, Nemoto T, et al: Coexpression of glucose transporter 1 and matrix metallo-proteinase-2 in human cancers. J Natl Cancer Inst 2002; 94: 1080-1091.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1080-1091
    • Ito, S.1    Fukusato, T.2    Nemoto, T.3
  • 53
    • 0033612152 scopus 로고    scopus 로고
    • Inhibition of glucose transporter gene expression by antisense nucleic acids in HL-60 leukemia cells
    • Chan JY, Kong SK, Choy YM, et al: Inhibition of glucose transporter gene expression by antisense nucleic acids in HL-60 leukemia cells. Life Sci 1999; 65: 63-70.
    • (1999) Life Sci , vol.65 , pp. 63-70
    • Chan, J.Y.1    Kong, S.K.2    Choy, Y.M.3
  • 54
    • 0029444685 scopus 로고
    • Antisense GLUT1 RNA suppresses the transforming phenotypes of NIH 3T3 cells transformed by N- Ras
    • Choi JW, Yoon DJ, Lee HW, et al: Antisense GLUT1 RNA suppresses the transforming phenotypes of NIH 3T3 cells transformed by N- Ras. Yonsei Med J 1995; 36: 480-486.
    • (1995) Yonsei Med J , vol.36 , pp. 480-486
    • Choi, J.W.1    Yoon, D.J.2    Lee, H.W.3
  • 55
    • 0033710395 scopus 로고    scopus 로고
    • Glut-1 translocation in FRTL-5 thyroid cells: Role of phosphatidylinositol 3-kinase and N-glyco-sylation
    • Samih N, Hovsepian S, Aouani A, et al: Glut-1 translocation in FRTL-5 thyroid cells: role of phosphatidylinositol 3-kinase and N-glyco-sylation. Endocrinology 2000; 141: 4146-4155.
    • (2000) Endocrinology , vol.141 , pp. 4146-4155
    • Samih, N.1    Hovsepian, S.2    Aouani, A.3
  • 56
    • 58149172000 scopus 로고    scopus 로고
    • Apigenin inhibits the GLUT-1 glucose transporter and the phosphoinositide 3-kinase/Akt pathway in human pancreatic cancer cells
    • Melstrom LG, Salabat MR, Ding XZ, et al: Apigenin inhibits the GLUT-1 glucose transporter and the phosphoinositide 3-kinase/Akt pathway in human pancreatic cancer cells. Pancreas 2008; 37: 426-431.
    • (2008) Pancreas , vol.37 , pp. 426-431
    • Melstrom, L.G.1    Salabat, M.R.2    Ding, X.Z.3
  • 57
    • 32944465388 scopus 로고    scopus 로고
    • Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway
    • Granville CA, Memmott RM, Gills JJ, et al: Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway. Clin Cancer Res 2006; 12: 679-689.
    • (2006) Clin Cancer Res , vol.12 , pp. 679-689
    • Granville, C.A.1    Memmott, R.M.2    Gills, J.J.3
  • 58
    • 66649084445 scopus 로고    scopus 로고
    • Expression and correlation of hypoxia-inducible factor-1α, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis
    • Wang W, Xu GL, Jia WD, et al: Expression and correlation of hypoxia-inducible factor-1α, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis. J Int Med Res 2009; 37: 417-425.
    • (2009) J Int Med Res , vol.37 , pp. 417-425
    • Wang, W.1    Xu, G.L.2    Jia, W.D.3
  • 59
    • 77950922592 scopus 로고    scopus 로고
    • Practical strategies for suppressing hypoxia- inducible factor activity in cancer therapy
    • McCarty MF, Barroso-Aranda J, Contreras F: Practical strategies for suppressing hypoxia- inducible factor activity in cancer therapy. Med Hypotheses 2010; 74: 789-797.
    • (2010) Med Hypotheses , vol.74 , pp. 789-797
    • McCarty, M.F.1    Barroso-Aranda, J.2    Contreras, F.3
  • 60
    • 78650833108 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer management
    • Seeber LM, Zweemer RP, Verheijen RH, et al: Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer management. Obstet Gynecol Int 2010; 2010: 580971.
    • (2010) Obstet Gynecol Int , vol.2010 , pp. 580971
    • Seeber, L.M.1    Zweemer, R.P.2    Verheijen, R.H.3
  • 61
    • 0035027828 scopus 로고    scopus 로고
    • Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells
    • Seagroves TN, Ryan HE, Lu H, et al: Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol Cell Biol 2001; 21: 3436-3444.
    • (2001) Mol Cell Biol , vol.21 , pp. 3436-3444
    • Seagroves, T.N.1    Ryan, H.E.2    Lu, H.3
  • 62
    • 73949140017 scopus 로고    scopus 로고
    • Clinicopathological implications of expressions of hypoxia-related molecules in esophageal superficial squamous cell carcinoma
    • Ogane N, Yasuda M, Shimizu M, et al: Clinicopathological implications of expressions of hypoxia-related molecules in esophageal superficial squamous cell carcinoma. Ann Diagn Pathol 2010; 14: 23-29.
    • (2010) Ann Diagn Pathol , vol.14 , pp. 23-29
    • Ogane, N.1    Yasuda, M.2    Shimizu, M.3
  • 63
    • 37249067628 scopus 로고    scopus 로고
    • Glut-1 as a therapeutic target: Increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies
    • Evans A, Bates V, Troy H, et al: Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies. Cancer Chemother Pharmacol 2008; 61: 377-393.
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 377-393
    • Evans, A.1    Bates, V.2    Troy, H.3
  • 64
    • 60149093542 scopus 로고    scopus 로고
    • Intravenous injection of siRNA directed against hypoxia- inducible factors prolongs survival in a Lewis lung carcinoma cancer model
    • Kamlah F, Eul BG, Li S, et al: Intravenous injection of siRNA directed against hypoxia- inducible factors prolongs survival in a Lewis lung carcinoma cancer model. Cancer Gene Ther 2009; 16: 195-205.
    • (2009) Cancer Gene Ther , vol.16 , pp. 195-205
    • Kamlah, F.1    Eul, B.G.2    Li, S.3
  • 65
    • 0025067416 scopus 로고
    • Effects of 2-deoxyglucose on drug-sensitive and drug- resistant human breast cancer cells: Toxicity and magnetic resonance spectroscopy studies of metabolism
    • Kaplan O, Navon G, Lyon RC, et al: Effects of 2-deoxyglucose on drug-sensitive and drug- resistant human breast cancer cells: toxicity and magnetic resonance spectroscopy studies of metabolism. Cancer Res 1990; 50: 544-551.
    • (1990) Cancer Res , vol.50 , pp. 544-551
    • Kaplan, O.1    Navon, G.2    Lyon, R.C.3
  • 66
    • 0037163688 scopus 로고    scopus 로고
    • Evaluation of 2-deoxy- D-glucose as a chemotherapeutic agent: Mechanism of cell death
    • Aft RL, Zhang FW, Gius D: Evaluation of 2-deoxy- D-glucose as a chemotherapeutic agent: mechanism of cell death. Br J Cancer 2002; 87: 805-812.
    • (2002) Br J Cancer , vol.87 , pp. 805-812
    • Aft, R.L.1    Zhang, F.W.2    Gius, D.3
  • 67
    • 1642494855 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non- small cell lung cancers in vivo
    • Maschek G, Savaraj N, Priebe W, et al: 2-Deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non- small cell lung cancers in vivo. Cancer Res 2004; 64: 31-34.
    • (2004) Cancer Res , vol.64 , pp. 31-34
    • Maschek, G.1    Savaraj, N.2    Priebe, W.3
  • 68
    • 29144467160 scopus 로고    scopus 로고
    • Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression
    • Maher JC, Savaraj N, Priebe W, et al: Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression. Pancreas 2005; 30: e34-e39.
    • (2005) Pancreas , vol.30
    • Maher, J.C.1    Savaraj, N.2    Priebe, W.3
  • 69
    • 34248142302 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells
    • Simons AL, Ahmad IM, Mattson DM, et al: 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Cancer Res 2007; 67: 3364-3370.
    • (2007) Cancer Res , vol.67 , pp. 3364-3370
    • Simons, A.L.1    Ahmad, I.M.2    Mattson, D.M.3
  • 70
    • 77951234870 scopus 로고    scopus 로고
    • Differential responses of tumors and normal brain to the combined treatment of 2-DG and radiation in glioablastoma
    • Prasanna VK, Venkataramana NK, Dwarakanath BS, et al: Differential responses of tumors and normal brain to the combined treatment of 2-DG and radiation in glioablastoma. J Cancer Res Ther 2009; 5(suppl 1): S44-S47.
    • (2009) J Cancer Res Ther , vol.5 , Issue.SUPPL. 1
    • Prasanna, V.K.1    Venkataramana, N.K.2    Dwarakanath, B.S.3
  • 71
    • 77951227475 scopus 로고    scopus 로고
    • Enhancement of radiation and chemo- therapeutic drug responses by 2-deoxy-D-glucose in animal tumors
    • Gupta S, Farooque A, Adhikari JS, et al: Enhancement of radiation and chemo- therapeutic drug responses by 2-deoxy-D-glucose in animal tumors. J Cancer Res Ther 2009; 5(suppl 1): S16-S20.
    • (2009) J Cancer Res Ther , vol.5 , Issue.SUPPL. 1
    • Gupta, S.1    Farooque, A.2    Adhikari, J.S.3
  • 72
    • 77951221371 scopus 로고    scopus 로고
    • Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: Present status and future prospects
    • Dwarakanath BS, Singh D, Banerji AK, et al: Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: present status and future prospects. J Cancer Res Ther 2009; 5(suppl 1): S21-S26.
    • (2009) J Cancer Res Ther , vol.5 , Issue.SUPPL. 1
    • Dwarakanath, B.S.1    Singh, D.2    Banerji, A.K.3
  • 73
    • 77649336663 scopus 로고    scopus 로고
    • Metabolic genes in cancer: Their roles in tumor progression and clinical implications
    • Furuta E, Okuda H, Kobayashi A, et al: Metabolic genes in cancer: their roles in tumor progression and clinical implications. Biochim Biophys Acta 2010; 1805: 141-152.
    • (2010) Biochim Biophys Acta , vol.1805 , pp. 141-152
    • Furuta, E.1    Okuda, H.2    Kobayashi, A.3
  • 74
    • 34347399139 scopus 로고    scopus 로고
    • Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: Effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs
    • Jason TL, Berg RW, Vincent MD, et al: Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs. Gene Expr 2007; 13: 227-239.
    • (2007) Gene Expr , vol.13 , pp. 227-239
    • Jason, T.L.1    Berg, R.W.2    Vincent, M.D.3
  • 75
    • 34547126428 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) as cancer targets
    • Hunter AM, LaCasse EC, Korneluk RG: The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 2007; 12: 1543-1568.
    • (2007) Apoptosis , vol.12 , pp. 1543-1568
    • Hunter, A.M.1    Lacasse, E.C.2    Korneluk, R.G.3
  • 76
    • 34547615934 scopus 로고    scopus 로고
    • Non-specific effects of siRNAs on tumor cells with implications on therapeutic applicability using RNA interference
    • Tschaharganeh D, Ehemann V, Nussbaum T, et al: Non-specific effects of siRNAs on tumor cells with implications on therapeutic applicability using RNA interference. Pathol Oncol Res 2007; 13: 84-90.
    • (2007) Pathol Oncol Res , vol.13 , pp. 84-90
    • Tschaharganeh, D.1    Ehemann, V.2    Nussbaum, T.3
  • 77
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D, Rossi JJ: The promises and pitfalls of RNA-interference-based therapeutics. Nature 2009; 457: 426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 78
    • 77952688315 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo- controlled study of an RNAi-based therapy directed against respiratory syncytial virus
    • DeVincenzo J, Lambkin-Williams R, Wilkinson T, et al: A randomized, double-blind, placebo- controlled study of an RNAi-based therapy directed against respiratory syncytial virus. Proc Natl Acad Sci USA 2010; 107: 8800-8805.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8800-8805
    • DeVincenzo, J.1    Lambkin-Williams, R.2    Wilkinson, T.3
  • 79
    • 31444440290 scopus 로고    scopus 로고
    • Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1
    • Shen J, Samul R, Silva RL, et al: Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1. Gene Ther 2006; 13: 225-234.
    • (2006) Gene Ther , vol.13 , pp. 225-234
    • Shen, J.1    Samul, R.2    Silva, R.L.3
  • 80
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 81
    • 17844383964 scopus 로고    scopus 로고
    • Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
    • Ramanathan A, Wang C, Schreiber SL: Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci U S A 2005; 102: 5992-5997.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5992-5997
    • Ramanathan, A.1    Wang, C.2    Schreiber, S.L.3
  • 82
    • 12944262229 scopus 로고    scopus 로고
    • Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
    • Macheda ML, Rogers S, Best JD: Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol 2005; 202: 654-662.
    • (2005) J Cell Physiol , vol.202 , pp. 654-662
    • Macheda, M.L.1    Rogers, S.2    Best, J.D.3


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