Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

Laboratory Investigation

Volumn 91, Issue 1, 2011, Pages 24-32

  Hassane, Sabrine ^a   Claij, Nanna ^a   Jodar, Martine ^b   Dedman, Alexandra ^b   Lauritzen, Inger ^b   Duprat, Fabrice ^b   Koenderman, Jorine S ^a   Van Der Wal, Annemieke ^a   Breuning, Martijn H ^a   De Heer, Emile ^a   Honore, Eric ^b   Deruiter, Marco C ^a   Peters, Dorien J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

glomerular cysts; hypertension; Pkd1; polycystic kidney disease; SM22Cre; Tie2Cre

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ACETYLCHOLINE; ANGIOTENSIN II; CRE RECOMBINASE; PHENYLEPHRINE; POLYCYSTIN 1; POLYCYSTIN 2; POTASSIUM CHLORIDE; SEROTONIN; TRANSGELIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTICLE; BILE DUCT; BOWMAN CAPSULE; CONTROLLED STUDY; CYST; DISSECTING ANEURYSM; ENDOTHELIUM CELL; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; HEART MUSCLE CONTRACTILITY; HEART RATE; HISTOPATHOLOGY; HYPERTENSION; IN VIVO STUDY; KIDNEY POLYCYSTIC DISEASE; MOUSE; MYOGRAPHY; NONHUMAN; OUTCOME ASSESSMENT; PANCREAS DUCT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STAINING; SYSTOLIC BLOOD PRESSURE;

ANIMALS; AORTA; BLOOD PRESSURE; ENDOTHELIAL CELLS; FEMALE; HEART RATE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; POLYCYSTIC KIDNEY DISEASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRPP CATION CHANNELS;

EID: 78650770897     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.159     Document Type: Article

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