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Volumn 18, Issue 14, 2009, Pages 2532-2542

Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CRE RECOMBINASE; POLYCYSTIN 1; PROTEIN FJX1; S (1,2 DICHLOROVINYL)CYSTEINE; TAMOXIFEN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 67649884993     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp190     Document Type: Article
Times cited : (120)

References (43)
  • 1
    • 0025247229 scopus 로고
    • Autosomal dominant polycystic kidney disease: More than a renal disease
    • Gabow, P.A. (1990) Autosomal dominant polycystic kidney disease: More than a renal disease. Am. J. Kidney Dis., 16, 403-413.
    • (1990) Am. J. Kidney Dis , vol.16 , pp. 403-413
    • Gabow, P.A.1
  • 2
    • 0026466656 scopus 로고    scopus 로고
    • Peters, D.J.M. and Sandkuijl, L.A. (1992) In Breuning, M.H., Devoto, M. and Romeo, G. (eds), Contributions to Nephrology, 97: Polycystic Kidney Disease. Karger, Basel, pp. 128-139.
    • Peters, D.J.M. and Sandkuijl, L.A. (1992) In Breuning, M.H., Devoto, M. and Romeo, G. (eds), Contributions to Nephrology, Vol. 97: Polycystic Kidney Disease. Karger, Basel, pp. 128-139.
  • 3
    • 0028278058 scopus 로고    scopus 로고
    • The European Polycystic Kidney Disease ConsortiumWard, C.J., Peral, B., Hughes, J., Thomas, S., Gamble, V., MacCarthy, A., Sloane-Stanley, J., Buckle, V., Kearney, L.H.D., Ratcliffe, P. et al. (1994) The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell, 77, 881-894.
    • The European Polycystic Kidney Disease ConsortiumWard, C.J., Peral, B., Hughes, J., Thomas, S., Gamble, V., MacCarthy, A., Sloane-Stanley, J., Buckle, V., Kearney, L.H.D., Ratcliffe, P. et al. (1994) The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell, 77, 881-894.
  • 5
    • 0030582668 scopus 로고    scopus 로고
    • The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease
    • Qian, F.J., Watnick, T.J., Onuchic, L.F. and Germino, G.G. (1996) The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease. Cell, 87, 979-987.
    • (1996) Cell , vol.87 , pp. 979-987
    • Qian, F.J.1    Watnick, T.J.2    Onuchic, L.F.3    Germino, G.G.4
  • 8
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Wilson, P.D. (2004) Polycystic kidney disease. N. Engl. J. Med., 350, 151-164.
    • (2004) N. Engl. J. Med , vol.350 , pp. 151-164
    • Wilson, P.D.1
  • 10
    • 0029756776 scopus 로고    scopus 로고
    • Abnormal postpartum renal development and cystogenesis in the bcl-2 (-/-) mouse
    • Sorenson, C.M., Padanilam, B.J. and Hammerman, M.R. (1996) Abnormal postpartum renal development and cystogenesis in the bcl-2 (-/-) mouse. Am. J. Physiol., 271, F184-F193.
    • (1996) Am. J. Physiol , vol.271
    • Sorenson, C.M.1    Padanilam, B.J.2    Hammerman, M.R.3
  • 11
    • 0025801311 scopus 로고
    • c-myc as an inducer of polycystic kidney disease in transgenic mice
    • Trudel, M., D'Agati, V. and Costantini, F. (1991) c-myc as an inducer of polycystic kidney disease in transgenic mice. Kidney Int., 39 665-671.
    • (1991) Kidney Int , vol.39 , pp. 665-671
    • Trudel, M.1    D'Agati, V.2    Costantini, F.3
  • 12
    • 0035921733 scopus 로고    scopus 로고
    • Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene
    • Saadi-Kheddouci, S., Berrebi, D., Romagnolo, B., Cluzeaud, F., Peuchmaur, M., Kahn, A., Vandewalle, A. and Perret, C. (2001) Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene. Oncogene, 20, 5972-5981.
    • (2001) Oncogene , vol.20 , pp. 5972-5981
    • Saadi-Kheddouci, S.1    Berrebi, D.2    Romagnolo, B.3    Cluzeaud, F.4    Peuchmaur, M.5    Kahn, A.6    Vandewalle, A.7    Perret, C.8
  • 14
    • 33745034469 scopus 로고    scopus 로고
    • Transgenic mice expressing tamoxifen-inducible Cre for somatic gene modification in renal epithelial cells
    • Lantinga-van Leeuwen, I.S., Leonhard, W., van der Wal, A., Breuning, M.H., De Heer, E. and Peters, D.J.M. (2006) Transgenic mice expressing tamoxifen-inducible Cre for somatic gene modification in renal epithelial cells. Genesis, 44, 225-232.
    • (2006) Genesis , vol.44 , pp. 225-232
    • Lantinga-van Leeuwen, I.S.1    Leonhard, W.2    van der Wal, A.3    Breuning, M.H.4    De Heer, E.5    Peters, D.J.M.6
  • 15
    • 36249030528 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice
    • Lantinga-van Leeuwen, I.S., Leonhard, W.N., van der Wal, A., Breuning, M.H., De Heer, E. and Peters, D.J. (2007) Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice. Hum. Mol. Genet., 16, 3188-3196.
    • (2007) Hum. Mol. Genet , vol.16 , pp. 3188-3196
    • Lantinga-van Leeuwen, I.S.1    Leonhard, W.N.2    van der Wal, A.3    Breuning, M.H.4    De Heer, E.5    Peters, D.J.6
  • 16
    • 36849037019 scopus 로고    scopus 로고
    • A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
    • Piontek, K., Menezes, L.F., Garcia-Gonzalez, M.A., Huso, D.L. and Germino, G.G. (2007) A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1. Nat. Med., 13, 1490-1495.
    • (2007) Nat. Med , vol.13 , pp. 1490-1495
    • Piontek, K.1    Menezes, L.F.2    Garcia-Gonzalez, M.A.3    Huso, D.L.4    Germino, G.G.5
  • 18
    • 57149094707 scopus 로고    scopus 로고
    • Pkd1 inactivation induced in adulthood produces focal cystic disease
    • Takakura, A., Contrino, L., Beck, A.W. and Zhou, J. (2008) Pkd1 inactivation induced in adulthood produces focal cystic disease. J. Am. Soc. Nephrol., 19, 2351-2363.
    • (2008) J. Am. Soc. Nephrol , vol.19 , pp. 2351-2363
    • Takakura, A.1    Contrino, L.2    Beck, A.W.3    Zhou, J.4
  • 20
    • 44349116202 scopus 로고    scopus 로고
    • Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
    • Patel, V., Li, L., Cobo-Stark, P., Shao, X., Somlo, S., Lin, F. and Igarashi, P. (2008) Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum. Mol. Genet., 17, 1578-1590.
    • (2008) Hum. Mol. Genet , vol.17 , pp. 1578-1590
    • Patel, V.1    Li, L.2    Cobo-Stark, P.3    Shao, X.4    Somlo, S.5    Lin, F.6    Igarashi, P.7
  • 22
    • 0023761451 scopus 로고
    • Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes
    • Lock, E.A. (1988) Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes. Crit. Rev. Toxicol., 19, 23-42.
    • (1988) Crit. Rev. Toxicol , vol.19 , pp. 23-42
    • Lock, E.A.1
  • 23
    • 0023003510 scopus 로고
    • Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane
    • Lash, L.H., Elfarra, A.A. and Anders, M.W. (1986) Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane. J. Biol. Chem., 261, 5930-5935.
    • (1986) J. Biol. Chem , vol.261 , pp. 5930-5935
    • Lash, L.H.1    Elfarra, A.A.2    Anders, M.W.3
  • 24
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano, Y. and Kypta, R. (2003) Secreted antagonists of the Wnt signalling pathway. J. Cell Sci., 116, 2627-2634.
    • (2003) J. Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 25
    • 41149161142 scopus 로고    scopus 로고
    • Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface
    • Traister, A., Shi, W. and Filmus, J. (2008) Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface. Biochem. J., 410, 503-511.
    • (2008) Biochem. J , vol.410 , pp. 503-511
    • Traister, A.1    Shi, W.2    Filmus, J.3
  • 26
    • 56149097603 scopus 로고    scopus 로고
    • Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
    • Jonassen, J.A., San Agustin, J., Follit, J.A. and Pazour, G.J. (2008) Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J. Cell. Biol., 183 377-384.
    • (2008) J. Cell. Biol , vol.183 , pp. 377-384
    • Jonassen, J.A.1    San Agustin, J.2    Follit, J.A.3    Pazour, G.J.4
  • 27
    • 16844375093 scopus 로고    scopus 로고
    • Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation
    • Nishio, S., Hatano, M., Nagata, M., Horie, S., Koike, T., Tokuhisa, T. and Mochizuki, T. (2005) Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J. Clin. Invest., 115, 910-918.
    • (2005) J. Clin. Invest , vol.115 , pp. 910-918
    • Nishio, S.1    Hatano, M.2    Nagata, M.3    Horie, S.4    Koike, T.5    Tokuhisa, T.6    Mochizuki, T.7
  • 28
    • 47749093500 scopus 로고    scopus 로고
    • Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains
    • Ishikawa, H.O., Takeuchi, H., Haltiwanger, R.S. and Irvine, K.D. (2008) Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains. Science, 321, 401-404.
    • (2008) Science , vol.321 , pp. 401-404
    • Ishikawa, H.O.1    Takeuchi, H.2    Haltiwanger, R.S.3    Irvine, K.D.4
  • 31
    • 50249138316 scopus 로고    scopus 로고
    • Tight junction composition is altered in the epithelium of polycystic kidneys
    • Yu, A., Kanzawa, S., Usorov, A., Lantinga-van Leeuwen, I. and Peters, D. (2008) Tight junction composition is altered in the epithelium of polycystic kidneys. J. Pathol., 216, 120-128.
    • (2008) J. Pathol , vol.216 , pp. 120-128
    • Yu, A.1    Kanzawa, S.2    Usorov, A.3    Lantinga-van Leeuwen, I.4    Peters, D.5
  • 32
    • 0032831465 scopus 로고    scopus 로고
    • The PKD1 gene product, 'polycystin-1', is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia
    • Wilson, P.D., Geng, L., Li, X. and Burrow, C.R. (1999) The PKD1 gene product, 'polycystin-1', is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia. Lab. Invest., 79, 1311-1323.
    • (1999) Lab. Invest , vol.79 , pp. 1311-1323
    • Wilson, P.D.1    Geng, L.2    Li, X.3    Burrow, C.R.4
  • 34
    • 0036900629 scopus 로고    scopus 로고
    • Polycystin-2 expression is increased following experimental ischaemic renal injury
    • Zhao, Y., Haylor, J.L. and Ong, A.C. (2002) Polycystin-2 expression is increased following experimental ischaemic renal injury. Nephrol. Dial. Transplant., 17, 2138-2144.
    • (2002) Nephrol. Dial. Transplant , vol.17 , pp. 2138-2144
    • Zhao, Y.1    Haylor, J.L.2    Ong, A.C.3
  • 39
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse, R. (2005) Wnt signaling in disease and in development. Cell Res., 15, 28-32.
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 40
    • 0033532143 scopus 로고    scopus 로고
    • Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells
    • van de Water, B., Nagelkerke, J.F. and Stevens, J.L. (1999) Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells. J. Biol. Chem., 274, 13328-13337.
    • (1999) J. Biol. Chem , vol.274 , pp. 13328-13337
    • van de Water, B.1    Nagelkerke, J.F.2    Stevens, J.L.3
  • 41
    • 41549137354 scopus 로고    scopus 로고
    • Quantification of Cre-mediated recombination by a novel strategy reveals a stable extra-chromosomal deletion-circle in mice
    • Leonhard, W.N., Roelfsema, J.H., Lantinga-van Leeuwen, I.S., Breuning, M.H. and Peters, D.J. (2008) Quantification of Cre-mediated recombination by a novel strategy reveals a stable extra-chromosomal deletion-circle in mice. BMC Biotechnol., 8, 18.
    • (2008) BMC Biotechnol , vol.8 , pp. 18
    • Leonhard, W.N.1    Roelfsema, J.H.2    Lantinga-van Leeuwen, I.S.3    Breuning, M.H.4    Peters, D.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.