Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids

Archives of Neurology

Volumn 62, Issue 5, 2005, Pages 730-736

  Baracca, Alessandra ^a   Solaini, Giancarlo ^a   Sgarbi, Gianluca ^b   Lenaz, Giorgio ^a   Baruzzi, Agostino ^a   Schapira, Anthony H V ^c   Martinuzzi, Andrea ^d   Carelli, Valerio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d SCIENTIFIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIGITONIN; GLUTAMIC ACID; MALIC ACID; MITOCHONDRIAL DNA; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIDECARENONE;

ARTICLE; BIOENERGY; CONTROLLED STUDY; CYBRID; FIBROBLAST; HUMAN; HUMAN CELL; LEBER HEREDITARY OPTIC NEUROPATHY; MITOCHONDRIAL RESPIRATION; OSTEOSARCOMA; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PATHOGENESIS; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VISUAL IMPAIRMENT;

ADENOSINE TRIPHOSPHATE; CELLS, CULTURED; CITRIC ACID; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; FIBROBLASTS; GLUTAMATES; HUMANS; HYBRID CELLS; MUTATION; OPTIC ATROPHY, HEREDITARY, LEBER; OXYGEN CONSUMPTION; SUCCINIC ACID;

EID: 18544384889     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.62.5.730     Document Type: Article

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