Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection

American Journal of Respiratory Cell and Molecular Biology

Volumn 44, Issue 1, 2010, Pages 118-126

  Eddleston, Jane ^a,b   Lee, Rachel U ^c,d   Doerner, Astrid M ^a   Herschbach, Jack ^a   Zuraw, Bruce L ^b,d  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c SCRIPPS CLINIC   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Cigarette smoke; Epithelial cells; Respiratory infections; Rhinovirus

Indexed keywords

BETA INTERFERON; CIGARETTE SMOKE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; POLYINOSINIC POLYCYTIDYLIC ACID; RANTES; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; VIRUS RNA;

ARTICLE; BRONCHUS MUCOSA; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; MEDIATOR; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY EPITHELIUM; RHINOVIRUS; RHINOVIRUS INFECTION; SIGNAL TRANSDUCTION; VIRUS ACTIVATION; VIRUS LOAD; VIRUS STRAIN;

CELL LINE; CHEMOKINE CCL5; CHEMOKINE CXCL10; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; POLY I-C; RESPIRATORY MUCOSA; RHINOVIRUS; RNA, MESSENGER; RNA, VIRAL; SMOKE; SMOKING; STAT1 TRANSCRIPTION FACTOR; TIME FACTORS; VIRAL LOAD; VIRUS REPLICATION;

HUMAN RHINOVIRUS 16; RHINOVIRUS;

EID: 78650663097     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0266OC     Document Type: Article

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