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Volumn 6, Issue 1, 2011, Pages 94-103

A Combined Ligand- and Structure-Based Virtual Screening Protocol Identifies Submicromolar PPARγPartial Agonists

Author keywords

Diabetes; Drug design; Partial agonists; PPAR ; Virtual screening

Indexed keywords

(2) 2 [2 ({1 [(4 METHOXYPHENYL)CARBONYL] 2 METHYL 5 (TRIFLUOROMETHOXY) 1H INDOL 3 YL}METHYL)PHENOXY]PROPANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; UNCLASSIFIED DRUG;

EID: 78650636079     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000428     Document Type: Article
Times cited : (30)

References (48)
  • 28
    • 78650662808 scopus 로고    scopus 로고
    • PDB ligand annotations are available from the PDB Ligand Expo; (Last accessed: November 16, 2010).
    • PDB ligand annotations are available from the PDB Ligand Expo; (Last accessed: November 16, 2010).
  • 29
    • 78650664934 scopus 로고    scopus 로고
    • PubChem BioAssay AID: 631 is available here: (Last accessed: November 16, 2010).
    • PubChem BioAssay AID: 631 is available here: (Last accessed: November 16, 2010).
  • 30
    • 78650639394 scopus 로고    scopus 로고
    • PubChem BioAssay AID: 1032 is available here: (Last accessed: November 16, 2010).
    • PubChem BioAssay AID: 1032 is available here: (Last accessed: November 16, 2010).
  • 31
    • 78650657785 scopus 로고    scopus 로고
    • PubChem BioAssay AID: 731 is available here: (Last accessed: November 16, 2010).
    • PubChem BioAssay AID: 731 is available here: (Last accessed: November 16, 2010).
  • 36
    • 78650658654 scopus 로고    scopus 로고
    • Data was retrieved from the ChEMBL database on May 13, 2010; (Last accessed: November 16, 2010).
    • Data was retrieved from the ChEMBL database on May 13, 2010; (Last accessed: November 16, 2010).
  • 37
    • 78650663282 scopus 로고    scopus 로고
    • Target Informatics Platform (TIP), Version 2010.4006, Eidogen-Sertanty Inc., San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
    • Target Informatics Platform (TIP), Version 2010.4006, Eidogen-Sertanty Inc., (San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
  • 38
    • 78650649909 scopus 로고    scopus 로고
    • Eidogen Visualization Environment (EVE), Version 4.1, Eidogen-Sertanty Inc., San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
    • Eidogen Visualization Environment (EVE), Version 4.1, Eidogen-Sertanty Inc., (San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
  • 39
    • 78650645778 scopus 로고    scopus 로고
    • Omega2, Version 2.3.2, OpenEye Scientific Software Inc., Santa Fe, NM, USA), 2008; (Last accessed: November 16, 2010).
    • Omega2, Version 2.3.2, OpenEye Scientific Software Inc., (Santa Fe, NM, USA), 2008; (Last accessed: November 16, 2010).
  • 40
    • 78650646257 scopus 로고    scopus 로고
    • ROCS, Version 2.3.1, OpenEye Scientific Software Inc., Santa Fe, NM, USA), 2008; (Last accessed: November 16, 2010).
    • ROCS, Version 2.3.1, OpenEye Scientific Software Inc., (Santa Fe, NM, USA), 2008; (Last accessed: November 16, 2010).
  • 42
    • 78650638411 scopus 로고    scopus 로고
    • Maestro, Version 9.0, Schrödinger LLC., Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
    • Maestro, Version 9.0, Schrödinger LLC., (Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
  • 43
    • 78650631970 scopus 로고    scopus 로고
    • LigPrep, Version 2.3, Schrödinger LLC., Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
    • LigPrep, Version 2.3, Schrödinger LLC., (Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
  • 45
    • 78650638156 scopus 로고    scopus 로고
    • Glide, Version 5.0, Schrödinger LLC., Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
    • Glide, Version 5.0, Schrödinger LLC., (Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
  • 46
    • 78650661849 scopus 로고    scopus 로고
    • Pipeline Pilot, Version 7.0, Accelrys Software Inc., San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
    • Pipeline Pilot, Version 7.0, Accelrys Software Inc., (San Diego, CA, USA), 2008; (Last accessed: November 16, 2010).
  • 47
    • 78650644596 scopus 로고    scopus 로고
    • W. L. DeLano, The PyMOL Molecular Graphics System, Version 1.2, Schrödinger LLC., Portland, OR, USA), 2009; (Last accessed: November 16, 2010).
    • W. L. DeLano, The PyMOL Molecular Graphics System, Version 1.2, Schrödinger LLC., (Portland, OR, USA), 2009; (Last accessed: November 16, 2010).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.