Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for β-selection and tCr repertoire formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 46, 2010, Pages 19979-19984

  Ishikawa, Eri ^a   Miyake, Yasunobu ^a   Hara, Hiromitsu ^b   Saito, Takashi ^c,d   Yamasaki, Sho ^a,c  

^a KYUSHU UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Signal transduction; Thymic selection

Indexed keywords

PRE T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ALLELIC EXCLUSION; ANIMAL CELL; ANIMAL EXPERIMENT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL SELECTION; CELL SURFACE; CLONAL VARIATION; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GAMMA DELTA T LYMPHOCYTE; GENE TARGETING; GERM LINE; INTERNALIZATION; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS; WILD TYPE;

MUS;

EID: 78650576199     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1011228107     Document Type: Article

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