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2
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0028979704
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Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells
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of special interest. See annotation [3].
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Ono S, Ohno H, Saito T. Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells. of special interest Immunity. 2:1995;639-644 See annotation [3].
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Ono, S.1
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0028800991
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Physical dissociation of the TCR-CD3 complex accompanies receptor ligation
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of special interest. Along with [2], this paper provides a dynamic view of the components of TCR-CD3 complexes expressed at the surface of normal T cells.
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Kishimoto H, Kubo RT, Yurifuji H, Nakayama T, Asano Y, Tada T. Physical dissociation of the TCR-CD3 complex accompanies receptor ligation. of special interest J Exp Med. 182:1995;1997-2006 Along with [2], this paper provides a dynamic view of the components of TCR-CD3 complexes expressed at the surface of normal T cells.
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0027501806
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T cell development in mice lacking the CD3ζ/η gene
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Malissen M, Gillet A, Rocha B, Trucy J, Vivier E, Boyer C, Köntgen G, Brun N, Mazza G, Spanopoulou E, et al. T cell development in mice lacking the CD3ζ/η gene. EMBO J. 12:1993;4347-4355.
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0026601919
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Role of CD3δ in surface expression of the T cell antigen receptor/CD3 complex and in activation for killing analyzed with CD3δ negative cytolytic T lymphocyte variant
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Buferne M, Luton F, Letourneur F, Hoeveler A, Couez D, Barad M, Malissen B, Schmitt-Verhulst A-M, Boyer C. Role of CD3δ in surface expression of the T cell antigen receptor/CD3 complex and in activation for killing analyzed with CD3δ negative cytolytic T lymphocyte variant. J Immunol. 148:1992;657-664.
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0026559309
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Failure to synthesize the CD3γ chain. Consequences for T cell antigen receptor assembly, processing and expression
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0028805853
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Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
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of special interest. This paper shows that RAG-1 and RAG-2 proteins are sufficient to carry out double-strand breaks at V(D)J recombination signal sequences.
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McBlane, J.F.1
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Gellert, M.6
Oettinger, M.A.7
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10
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0028793809
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Expression of genes encoding the pre-T cell receptor and CD3 complex during thymus development
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Wilson, A.1
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11
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0026485046
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Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
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Lafaille, J.J.6
Wang, L.7
Ichikawa, Y.8
Jaenisch, R.9
Hooper, M.L.10
Tonegawa, S.11
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12
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0027406812
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Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes
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Shinkai Y, Koyasu S, Nakayama KI, Murphy KM, Loh DY, Reinherz EL, Alt FW. Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science. 259:1993;822-825.
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Shinkai, Y.1
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Alt, F.W.7
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13
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0026613009
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Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells
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Philpott KL, Viney JL, Kay G, Rastan S, Gardiner EM, Chae S, Hayday AC, Owen MJ. Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells. Science. 256:1992;1448-1452.
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Philpott, K.L.1
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Chae, S.6
Hayday, A.C.7
Owen, M.J.8
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14
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0027375004
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A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor β chain and a 33 kd glycoprotein
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Groettrup M, Ungewiss K, Azogui O, Palacios R, Owen MJ, Hayday AC, Von Boehmer H. A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor β chain and a 33 kd glycoprotein. Cell. 75:1993;283-294.
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Groettrup, M.1
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Owen, M.J.5
Hayday, A.C.6
Von Boehmer, H.7
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15
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0028021048
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Analysis and expression of a cloned pre-T cell receptor gene
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of special interest. This paper describes the cloning of the gene encoding the pre-T cell receptor (pTα).
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Saint-Ruf C, Ungewiss K, Groettrum M, Bruno L, Fehling HJ, Von Boehmer H. Analysis and expression of a cloned pre-T cell receptor gene. of special interest Science. 266:1994;1208-1212 This paper describes the cloning of the gene encoding the pre-T cell receptor (pTα).
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Saint-Ruf, C.1
Ungewiss, K.2
Groettrum, M.3
Bruno, L.4
Fehling, H.J.5
Von Boehmer, H.6
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16
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0029111379
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Genomic structure and chromosomal location of the mouse pre-T-cell receptor alpha gene
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Fehling, H.J.1
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Mattei, M.-G.3
Saint-Ruf, C.4
Von Boehmer, H.5
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17
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0029000949
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Intra- and extra-thymic expression of the pre-T cell receptor α gene
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Bruno L, Rocha B, Rolink A, Von Boehmer H, Rodewald H-R. Intra- and extra-thymic expression of the pre-T cell receptor α gene. Eur J Immunol. 25:1995;1877-1882.
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Rodewald, H.-R.5
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0028956603
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Crystal structure of the β chain of α T cell antigen receptor
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Bentley GA, Boulot G, Karjalainen K, Mariuzza RA. Crystal structure of the β chain of α T cell antigen receptor. Science. 267:1995;1984-1987.
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Bentley, G.A.1
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0026051962
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Surface expression of a T cell receptor β (TCR-β) chain in the absence of TCR-α, -δ, and -γ proteins
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Hashimoto, Y.7
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21
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0029119248
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Characterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice
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of special interest. This paper reports on the structural characterization of the pre-TCR-CD3 complexes expressed at the surface of pre-T-cell lines. See also [20,22,23].
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Mombaerts P, Terhorst C, Jacks T, Tonegawa S, Sancho J. Characterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice. of special interest Proc Natl Acad Sci USA. 92:1995;7420-7424 This paper reports on the structural characterization of the pre-TCR-CD3 complexes expressed at the surface of pre-T-cell lines. See also [20,22,23].
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Proc Natl Acad Sci USA
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Mombaerts, P.1
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Tonegawa, S.4
Sancho, J.5
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22
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0026748748
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T cell receptor (TCR) β chain homodimers on the surface of immature but not mature α, γ, δ chain deficient T cell lines
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Groettrup M, Baron A, Griffiths G, Palacios R, Von Boehmer H. T cell receptor (TCR) β chain homodimers on the surface of immature but not mature α, γ, δ chain deficient T cell lines. EMBO J. 11:1992;2735-2746.
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Groettrup, M.1
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Griffiths, G.3
Palacios, R.4
Von Boehmer, H.5
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0027230682
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T cell receptor β chain dimers on immature thymocytes from normal mice
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Groettrup M, Von Boehmer H. T cell receptor β chain dimers on immature thymocytes from normal mice. Eur J Immunol. 23:1993;1393-1396.
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Groettrup, M.1
Von Boehmer, H.2
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24
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0029094319
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Altered T cell development in mice with a targeted mutation of the CD3-ε gene
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of special interest. Reports the generation of mice with targeted disruption of the CD3ε gene and indicates the importance of modules containing CD3ε for TCR β-selection.
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Malissen M, Gillet A, Ardouin L, Bouvier G, Trucy J, Ferrier P, Vivier E, Malissen B. Altered T cell development in mice with a targeted mutation of the CD3-ε gene. of special interest EMBO J. 14:1995;4641-4653 Reports the generation of mice with targeted disruption of the CD3ε gene and indicates the importance of modules containing CD3ε for TCR β-selection.
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EMBO J
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Malissen, M.1
Gillet, A.2
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Vivier, E.7
Malissen, B.8
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25
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Early T-cell development in CD3-deficient mice
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Malissen, M.7
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26
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0024790119
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Surface expression of CD3 in the absence of T cell receptor (TcR): Evidence for sorting of partial TcR/CD3 complexes in a post-endoplasmic reticulum compartment
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Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes
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Weist DL, Kearse KP, Shores EW, Singer A. Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes. J Exp Med. 180:1994;1375-1382.
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Weist, D.L.1
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Singer, A.4
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28
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0029072799
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The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes
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This paper indicates that CD3-γε and CD3δε dimers can escape the ER of immature thymocytes to be expressed at low levels on the cell surface in association with calnexin.
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Wiest DL, Burgess WH, McKean D, Kearse KP, Singer A. The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes. EMBO J. 14:1995;3425-3433 This paper indicates that CD3-γε and CD3δε dimers can escape the ER of immature thymocytes to be expressed at low levels on the cell surface in association with calnexin.
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EMBO J
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Wiest, D.L.1
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Wang, B.1
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30
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0028877062
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The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit
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of special interest. This paper analyzes the signaling function of the pre-TCR complexes expressed on pre-T cell lines and indicates that these complexes are functionally coupled to CD3ζ and to the ZAP-70 and Syk PTKs.
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Van Oers NSC, Von Boehmer H, Weiss A. The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit. of special interest J Exp Med. 182:1995;1585-1590 This paper analyzes the signaling function of the pre-TCR complexes expressed on pre-T cell lines and indicates that these complexes are functionally coupled to CD3ζ and to the ZAP-70 and Syk PTKs.
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0027199532
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T-cell development in mice that lack the ζ chain of the T cell antigen receptor complex
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Love PE, Shores EW, Johnson MD, Tremblay ML, Lee EJ, Grinberg A, Huang SP, Singer A, Westphal H. T-cell development in mice that lack the ζ chain of the T cell antigen receptor complex. Science. 261:1993;918-921.
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Love, P.E.1
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Grinberg, A.6
Huang, S.P.7
Singer, A.8
Westphal, H.9
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The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
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Malissen, B.6
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35
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0028986925
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CD3ε and CD3δ cytoplasmic domains can independently generate signals for T cell development and function
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of special interest. The CD3ε and CD3ζ ITAMs deliver qualitatively similar signals during the transition to the DP stage.
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Shinkai Y, Ma A, Cheng HL, Alt FW. CD3ε and CD3δ cytoplasmic domains can independently generate signals for T cell development and function. of special interest Immunity. 2:1995;401-411 The CD3ε and CD3ζ ITAMs deliver qualitatively similar signals during the transition to the DP stage.
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Immunity
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Shinkai, Y.1
Ma, A.2
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Alt, F.W.4
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0028051551
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Role of TCR ζ chain in T cell development and selection
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of special interest. The CD3-ζ ITAMs are dispensable for TCRβ and TCRαβ selection.
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Shore EW, Huang K, Tran T, Lee E, Grinberg A, Love PE. Role of TCR ζ chain in T cell development and selection. of special interest Science. 266:1994;1047-1050 The CD3-ζ ITAMs are dispensable for TCRβ and TCRαβ selection.
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Shore, E.W.1
Huang, K.2
Tran, T.3
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0028178440
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Fehling, H.J.1
Krotkova, A.2
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