-
1
-
-
0028157728
-
The IRS-1 signaling system
-
M.F. White The IRS-1 signaling system Curr Opin Genet Dev 4 1994 47 54
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 47-54
-
-
White, M.F.1
-
2
-
-
0028904053
-
Insulin action and the insulin signalling network
-
B. Cheatham, and C.R. Kahn Insulin action and the insulin signalling network Endocr Rev 16 1995 117 142
-
(1995)
Endocr Rev
, vol.16
, pp. 117-142
-
-
Cheatham, B.1
Kahn, C.R.2
-
3
-
-
34248166119
-
Insulin resistance following thermal injury: An animal study
-
X.-L. Chen, Z.-F. Xia, D.-F. Ben, J.-G. Tian, and D. Wei Insulin resistance following thermal injury: an animal study Burns 33 2007 480 483
-
(2007)
Burns
, vol.33
, pp. 480-483
-
-
Chen, X.-L.1
Xia, Z.-F.2
Ben, D.-F.3
Tian, J.-G.4
Wei, D.5
-
4
-
-
72049101882
-
Acute insulin resistance following injury
-
L. Li, and J.L. Messina Acute insulin resistance following injury Trends Endocrinol Metab 20 2009 429 435
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 429-435
-
-
Li, L.1
Messina, J.L.2
-
5
-
-
55249116335
-
Insulin resistance postburn: Underlying mechanisms and current therapeutic strategies
-
G.G. Gauglitz, D.N. Herndon, and M.G. Jeschke Insulin resistance postburn: underlying mechanisms and current therapeutic strategies J Burn Care Res 29 2008 683 694
-
(2008)
J Burn Care Res
, vol.29
, pp. 683-694
-
-
Gauglitz, G.G.1
Herndon, D.N.2
Jeschke, M.G.3
-
6
-
-
0018681047
-
Glucose requirements following burn injury: Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake
-
J.F. Burke, R.R. Wolfe, C.J. Mullany, D.E. Mathews, and D.M. Bier Glucose requirements following burn injury: parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake Ann Surg 190 1979 274 285
-
(1979)
Ann Surg
, vol.190
, pp. 274-285
-
-
Burke, J.F.1
Wolfe, R.R.2
Mullany, C.J.3
Mathews, D.E.4
Bier, D.M.5
-
7
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
A.R. Saltiel, and C.R. Kahn Insulin signalling and the regulation of glucose and lipid metabolism Nature 414 2001 799 806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
8
-
-
0028825748
-
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1): Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1
-
H. Kanety, R. Feinstein, M.Z. Papa, R. Hemi, and A. Karasik Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1): possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1 J Biol Chem 270 1995 23780 23784
-
(1995)
J Biol Chem
, vol.270
, pp. 23780-23784
-
-
Kanety, H.1
Feinstein, R.2
Papa, M.Z.3
Hemi, R.4
Karasik, A.5
-
9
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
G.S. Hotamisligil, P. Peraldi, A. Budavari, R. Ellis, M.F. White, and B.M. Spiegelman IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance Science 271 1996 665 668
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
10
-
-
0027193784
-
Plasma tumour necrosis factor-alpha (TNF-alpha) levels in patients with burns
-
S. Endo, K. Inada, Y. Yamada, T. Kasai, T. Takakuwa, and H. Nakae Plasma tumour necrosis factor-alpha (TNF-alpha) levels in patients with burns Burns 19 1993 124 127
-
(1993)
Burns
, vol.19
, pp. 124-127
-
-
Endo, S.1
Inada, K.2
Yamada, Y.3
Kasai, T.4
Takakuwa, T.5
Nakae, H.6
-
11
-
-
1642468286
-
Role of p38 mitogen-activated protein kinase in lung injury after burn trauma
-
X.L. Chen, Z.F. Xia, D.F. Ben, G.Q. Wang, and D. Wei Role of p38 mitogen-activated protein kinase in lung injury after burn trauma Shock 19 2003 475 479
-
(2003)
Shock
, vol.19
, pp. 475-479
-
-
Chen, X.L.1
Xia, Z.F.2
Ben, D.F.3
Wang, G.Q.4
Wei, D.5
-
12
-
-
0029020217
-
The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling
-
M.G. Myers Jr., T.C. Grammer, J. Brooks, E.M. Glasheen, L.M. Wang, and X.J. Sun The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling J Biol Chem 270 1995 11715 11718
-
(1995)
J Biol Chem
, vol.270
, pp. 11715-11718
-
-
Myers Jr., M.G.1
Grammer, T.C.2
Brooks, J.3
Glasheen, E.M.4
Wang, L.M.5
Sun, X.J.6
-
13
-
-
0029820085
-
The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1
-
L. Yenush, K.J. Makati, J. Smith-Hall, O. Ishibashi, M.G. Myers Jr., and M.F. White The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1 J Biol Chem 271 1996 24300 24306
-
(1996)
J Biol Chem
, vol.271
, pp. 24300-24306
-
-
Yenush, L.1
Makati, K.J.2
Smith-Hall, J.3
Ishibashi, O.4
Myers Jr., M.G.5
White, M.F.6
-
15
-
-
0034947869
-
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
-
A. Takano, I. Usui, T. Haruta, J. Kawahara, T. Uno, and M. Iwata Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin Mol Cell Biol 21 2001 5050 5062
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5050-5062
-
-
Takano, A.1
Usui, I.2
Haruta, T.3
Kawahara, J.4
Uno, T.5
Iwata, M.6
-
16
-
-
14244252683
-
Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes
-
F. Tremblay, A. Gagnon, A. Veilleux, A. Sorisky, and A. Marette Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes Endocrinology 146 2005 1328 1337
-
(2005)
Endocrinology
, vol.146
, pp. 1328-1337
-
-
Tremblay, F.1
Gagnon, A.2
Veilleux, A.3
Sorisky, A.4
Marette, A.5
-
17
-
-
0035836770
-
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1
-
O.N. Ozes, H. Akca, L.D. Mayo, J.A. Gustin, T. Maehama, and J.E. Dixon A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1 Proc Natl Acad Sci USA 98 2001 4640 4645
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4640-4645
-
-
Ozes, O.N.1
Akca, H.2
Mayo, L.D.3
Gustin, J.A.4
Maehama, T.5
Dixon, J.E.6
-
18
-
-
24144490615
-
Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver
-
S.Y. Park, Y.R. Cho, B.N. Finck, H.J. Kim, T. Higashimori, and E.G. Hong Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver Diabetes 54 2005 2514 2524
-
(2005)
Diabetes
, vol.54
, pp. 2514-2524
-
-
Park, S.Y.1
Cho, Y.R.2
Finck, B.N.3
Kim, H.J.4
Higashimori, T.5
Hong, E.G.6
-
19
-
-
73349137958
-
Hyperinsulinemic-euglycemic clamp to assess insulin sensitivity in vivo
-
J.K. Kim Hyperinsulinemic-euglycemic clamp to assess insulin sensitivity in vivo Methods Mol Biol 560 2009 221 238
-
(2009)
Methods Mol Biol
, vol.560
, pp. 221-238
-
-
Kim, J.K.1
-
20
-
-
38949125499
-
Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice
-
S. Lee, R. Muniyappa, X. Yan, H. Chen, L.Q. Yue, and E.G. Hong Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice Am J Physiol Endocrinol Metab 294 2008 E261 E270
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Lee, S.1
Muniyappa, R.2
Yan, X.3
Chen, H.4
Yue, L.Q.5
Hong, E.G.6
-
21
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
R.A. DeFronzo, J.D. Tobin, and R. Andres Glucose clamp technique: a method for quantifying insulin secretion and resistance Am J Physiol 237 3 1979 E214 E223
-
(1979)
Am J Physiol
, vol.237
, Issue.3
-
-
Defronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
22
-
-
52449093714
-
Pathophysiologic response to severe burn injury
-
M.G. Jeschke, D.L. Chinkes, C.C. Finnerty, G. Kulp, O.E. Suman, and W.B. Norbury Pathophysiologic response to severe burn injury Ann Surg 248 2008 387 401
-
(2008)
Ann Surg
, vol.248
, pp. 387-401
-
-
Jeschke, M.G.1
Chinkes, D.L.2
Finnerty, C.C.3
Kulp, G.4
Suman, O.E.5
Norbury, W.B.6
-
23
-
-
0030845178
-
Analysis of thermal injury-induced insulin resistance in rodents: Implication of postreceptor mechanisms
-
T. Ikezu, T. Okamoto, K. Yonezawa, R.G. Tompkins, and J.A. Martyn Analysis of thermal injury-induced insulin resistance in rodents: implication of postreceptor mechanisms J Biol Chem 272 1997 25289 25295
-
(1997)
J Biol Chem
, vol.272
, pp. 25289-25295
-
-
Ikezu, T.1
Okamoto, T.2
Yonezawa, K.3
Tompkins, R.G.4
Martyn, J.A.5
-
24
-
-
26444436274
-
Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: Role of IRS phosphorylation
-
Q. Zhang, E.A. Carter, B.Y. Ma, M. White, A.J. Fischman, and R.G. Tompkins Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation Life Sci 77 2005 3068 3077
-
(2005)
Life Sci
, vol.77
, pp. 3068-3077
-
-
Zhang, Q.1
Carter, E.A.2
Ma, B.Y.3
White, M.4
Fischman, A.J.5
Tompkins, R.G.6
-
25
-
-
78049321800
-
Post-burn hepatic insulin resistance is associated with ER stress
-
G.G. Gauglitz, S. Halder, D.F. Boehning, G.A. Kulp, D.N. Herndon, and Barral J.M. Post-burn hepatic insulin resistance is associated with ER stress Shock 2009 [Epub ahead of print]
-
(2009)
Shock
-
-
Gauglitz, G.G.1
Halder, S.2
Boehning, D.F.3
Kulp, G.A.4
Herndon, D.N.5
Barral, J.M.6
-
26
-
-
0031919049
-
Role of binding proteins to IRS-1 in insulin signaling
-
W. Ogawa, T. Matozaki, and M. Kasuga Role of binding proteins to IRS-1 in insulin signaling Mol Cell Biochem 182 1998 3 22
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 3-22
-
-
Ogawa, W.1
Matozaki, T.2
Kasuga, M.3
-
27
-
-
0031918624
-
The IRS-signalling system: A network of docking proteins that mediate insulin action
-
M.F. White The IRS-signalling system: a network of docking proteins that mediate insulin action Mol Cell Biochem 182 1998 3 11
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 3-11
-
-
White, M.F.1
-
28
-
-
0037018924
-
Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation
-
M.W. Greene, and R.S. Garofalo Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation Biochemistry 41 2002 7082 7091
-
(2002)
Biochemistry
, vol.41
, pp. 7082-7091
-
-
Greene, M.W.1
Garofalo, R.S.2
-
29
-
-
0030669392
-
A molecular basis for insulin resistance: Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
-
K. Paz, R. Hemi, D. LeRoith, A. Karasik, E. Elhanany, and H. Kanety A molecular basis for insulin resistance: elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation J Biol Chem 272 1997 29911 29918
-
(1997)
J Biol Chem
, vol.272
, pp. 29911-29918
-
-
Paz, K.1
Hemi, R.2
Leroith, D.3
Karasik, A.4
Elhanany, E.5
Kanety, H.6
-
31
-
-
55049092708
-
Temporal cytokine profiles in severely burned patients: A comparison of adults and children
-
C.C. Finnerty, M.G. Jeschke, D.N. Herndon, R. Gamelli, N. Gibran, and M. Klein Temporal cytokine profiles in severely burned patients: a comparison of adults and children Mol Med 14 2008 553 560
-
(2008)
Mol Med
, vol.14
, pp. 553-560
-
-
Finnerty, C.C.1
Jeschke, M.G.2
Herndon, D.N.3
Gamelli, R.4
Gibran, N.5
Klein, M.6
-
32
-
-
0031465447
-
Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
-
DOI 10.1074/jbc.272.50.31400
-
K. De Fea, and R.A. Roth Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase J Biol Chem 272 1997 31400 31406 (Pubitemid 28013276)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.50
, pp. 31400-31406
-
-
De Fea, K.1
Roth, R.A.2
-
33
-
-
0042570843
-
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
-
A. Virkamaki, K. Ueki, and C.R. Kahn Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance J Clin Invest 103 1999 931 943
-
(1999)
J Clin Invest
, vol.103
, pp. 931-943
-
-
Virkamaki, A.1
Ueki, K.2
Kahn, C.R.3
-
34
-
-
0034708832
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
-
V. Aguirre, T. Uchida, L. Yenush, R. Davis, and M.F. White The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) J Biol Chem 275 2000 9047 9054
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
36
-
-
13844262628
-
Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle
-
H. Sugita, M. Kaneki, M. Sugita, T. Yasukawa, S. Yasuhara, and J.A. Martyn Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle Am J Physiol Endocrinol Metab 288 2005 E585 E591
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Sugita, H.1
Kaneki, M.2
Sugita, M.3
Yasukawa, T.4
Yasuhara, S.5
Martyn, J.A.6
-
37
-
-
0038712570
-
Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes
-
P. Gual, T. Gonzalez, T. Gremeaux, R. Barres, Y. Le Marchand-Brustel, and J.F. Tanti Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes J Biol Chem 278 2003 26550 26557
-
(2003)
J Biol Chem
, vol.278
, pp. 26550-26557
-
-
Gual, P.1
Gonzalez, T.2
Gremeaux, T.3
Barres, R.4
Le Marchand-Brustel, Y.5
Tanti, J.F.6
-
38
-
-
0035312747
-
Regulation of translation initiation by FRAP/mTOR
-
GingrasAC, B. Raught, and N. Sonenberg Regulation of translation initiation by FRAP/mTOR Genes Dev 15 2001 807 826
-
(2001)
Genes Dev
, vol.15
, pp. 807-826
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
39
-
-
0037424466
-
Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation
-
M.W. Greene, H. Sakaue, L. Wang, D.R. Alessi, and R.A. Roth Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation J Biol Chem 278 2003 8199 8211
-
(2003)
J Biol Chem
, vol.278
, pp. 8199-8211
-
-
Greene, M.W.1
Sakaue, H.2
Wang, L.3
Alessi, D.R.4
Roth, R.A.5
-
40
-
-
0000085132
-
Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway
-
X.J. Sun, J.L. Goldberg, L.Y. Qiao, and J.J. Mitchell Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway Diabetes 48 1999 1359 1364
-
(1999)
Diabetes
, vol.48
, pp. 1359-1364
-
-
Sun, X.J.1
Goldberg, J.L.2
Qiao, L.Y.3
Mitchell, J.J.4
-
41
-
-
0035155272
-
Serine/threonine phosphorylation of IRS-1 triggers its degradation: Possible regulation by tyrosine phosphorylation
-
T.M. Pederson, D.L. Kramer, and C.M. Rondinone Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation Diabetes 50 2001 4 31
-
(2001)
Diabetes
, vol.50
, pp. 4-31
-
-
Pederson, T.M.1
Kramer, D.L.2
Rondinone, C.M.3
-
42
-
-
0035955629
-
Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2
-
L. Rui, T.L. Fisher, J. Thomas, and M.F. White Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2 J Biol Chem 276 2001 40362 40367
-
(2001)
J Biol Chem
, vol.276
, pp. 40362-40367
-
-
Rui, L.1
Fisher, T.L.2
Thomas, J.3
White, M.F.4
-
43
-
-
0042197413
-
Mammalian target of rapamycin: A new molecular target for breast cancer
-
M.M. Mita, A. Mita, and E.K. Rowinsky Mammalian target of rapamycin: a new molecular target for breast cancer Clin Breast Cancer 4 2003 126 137
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 126-137
-
-
Mita, M.M.1
Mita, A.2
Rowinsky, E.K.3
|