The first synthesis of [11C]SB-216763, a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3)

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 245-249

  Wang, Min ^a   Gao, Mingzhang ^a   Miller, Kathy D ^a   Sledge, George W ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

11C SB 216763; Alzheimer's disease; Cancer; Glycogen synthase kinase 3 (GSK 3); Positron emission tomography (PET); Radiosynthesis

Indexed keywords

(3 (2,4 DICHLOROPHENYL) 4 (1 [11C]METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE); 2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; MALEIC ANHYDRIDE; MALEIMIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IMAGING SYSTEM; POSITRON EMISSION TOMOGRAPHY;

CARBON RADIOISOTOPES; GLYCOGEN SYNTHASE KINASE 3; INDOLES; MALEIMIDES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN KINASE INHIBITORS; RADIOPHARMACEUTICALS;

EID: 78650522701     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.026     Document Type: Article

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