Novel components of the human metabolome: The identification, characterization and anti-inflammatory activity of two 5-androstene tetrols

Steroids

Volumn 76, Issue 1-2, 2011, Pages 145-155

  Ahlem, Clarence N ^a   Page, Theodore M ^a   Auci, Dominick L ^a   Kennedy, Michael R ^a   Mangano, Katia ^b   Nicoletti, Ferdinando ^b   Ge, Yu ^a   Huang, Yujin ^a   White, Steven K ^a   Villegas, Sonia ^a   Conrad, Douglas ^c   Wang, Angela ^c   Reading, Christopher L ^a   Frincke, James M ^a  

^a Harbor Biosciences Inc   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Androstene; Human; Inflammation; Metabolism; Metabolome; Tetrol

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ANDROST 5 ENE 3ALPHA,7ALPHA,16ALPHA,17BETA TETROL; ANDROST 5 ENE 3ALPHA,7BETA,16ALPHA,17BETA TETROL; ANDROST 5 ENE 3BETA,7ALPHA,16ALPHA,17BETA TETROL; ANDROST 5 ENE 3BETA,7BETA,16ALPHA,17BETA TETROL; ANDROSTENEDIOL DERIVATIVE; ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CHRONIC PROSTATITIS; COLITIS; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG STRUCTURE; DRUG TOLERABILITY; FEMALE; HUMAN; LUNG INJURY; MALE; MEMBRANE TRANSPORT; METABOLOME; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PLASMA; SOLUBILITY; URINE;

ADOLESCENT; ADULT; AGED; ANDROSTENOLS; ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MICE; MICE, INBRED STRAINS; MIDDLE AGED; MOLECULAR CONFORMATION; MULTIPLE SCLEROSIS; PROSTATITIS; RATS; SOLUBILITY; STEREOISOMERISM; YOUNG ADULT;

MURINAE; MUS; RODENTIA;

EID: 78650517754     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.10.005     Document Type: Article

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