Potent transglutaminase inhibitors, dithio β-aminoethyl ketones

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 377-379

  Ozaki, Shoichiro ^a   Ebisui, Etsuko ^a   Hamada, Kozo ^a,b   Suzuki, Akinobu Z ^a   Terauchi, Akiko ^a,b   Mikoshiba, Katsuhiko ^a,b  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Alzheimer's disease; Celiac disease; Dithio aminoethyl ketones; Huntington's disease; Parkinson's disease; Transglutaminase inhibitors

Indexed keywords

CYSTAMINE; DIMETHYL HOMOCYSTINE; DISULFIDE; DITHIO BETA AMINOETHYL KETONE DERIVATIVE; ENZYME INHIBITOR; PENICILLAMINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; THIOPHENE; UNCLASSIFIED DRUG;

ARTICLE; DISULFIDE BOND; IC 50;

DISULFIDES; ENZYME INHIBITORS; KETONES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES; TRANSGLUTAMINASES;

EID: 78650515365     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.136     Document Type: Article

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