-
1
-
-
66349099340
-
Fatty acid metabolism: Target for metabolic syndrome
-
Wakil SJ, Abu-Elheiga LA (2009) Fatty acid metabolism: Target for metabolic syndrome. J Lipid Res 50(Suppl):S138-143.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Wakil, S.J.1
Abu-Elheiga, L.A.2
-
3
-
-
0001217446
-
Evidence for the participation of biotin in the enzymic synthesis of fatty acids
-
Wakil SJ, Titchener EB, Gibson DM (1958) Evidence for the participation of biotin in the enzymic synthesis of fatty acids. Biochim Biophys Acta 29:225-226.
-
(1958)
Biochim Biophys Acta
, vol.29
, pp. 225-226
-
-
Wakil, S.J.1
Titchener, E.B.2
Gibson, D.M.3
-
4
-
-
0025021124
-
Identification of an isozymic form of acetyl-CoA carboxylase
-
Bianchi A, et al. (1990) Identification of an isozymic form of acetyl-CoA carboxylase. J Biol Chem 265:1502-1509.
-
(1990)
J Biol Chem
, vol.265
, pp. 1502-1509
-
-
Bianchi, A.1
-
5
-
-
0024459546
-
Formation of malonyl coenzyme A in rat heart. Identification and purification of an isozyme of A carboxylase from rat heart
-
Thampy KG (1989) Formation of malonyl coenzyme A in rat heart. Identification and purification of an isozyme of A carboxylase from rat heart. J Biol Chem 264:17631-17634.
-
(1989)
J Biol Chem
, vol.264
, pp. 17631-17634
-
-
Thampy, K.G.1
-
6
-
-
37349049251
-
Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2
-
Cho YS, et al. (2008) Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2. Proteins 70:268-272.
-
(2008)
Proteins
, vol.70
, pp. 268-272
-
-
Cho, Y.S.1
-
7
-
-
10944226843
-
A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product
-
Shen Y, Volrath SL, Weatherly SC, Elich TD, Tong L (2004) A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product. Mol Cell 16:881-891.
-
(2004)
Mol Cell
, vol.16
, pp. 881-891
-
-
Shen, Y.1
Volrath, S.L.2
Weatherly, S.C.3
Elich, T.D.4
Tong, L.5
-
8
-
-
0028085434
-
Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase
-
Waldrop GL, Rayment I, Holden HM (1994) Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase. Biochemistry 33:10249-10256.
-
(1994)
Biochemistry
, vol.33
, pp. 10249-10256
-
-
Waldrop, G.L.1
Rayment, I.2
Holden, H.M.3
-
9
-
-
0029646091
-
Structure of the biotinyl domain of acetylcoenzyme A carboxylase determined by MAD phasing
-
Athappilly FK, Hendrickson WA (1995) Structure of the biotinyl domain of acetylcoenzyme A carboxylase determined by MAD phasing. Structure 3:1407-1419.
-
(1995)
Structure
, vol.3
, pp. 1407-1419
-
-
Athappilly, F.K.1
Hendrickson, W.A.2
-
10
-
-
65349164657
-
The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist
-
Madauss KP, et al. (2009) The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist. Acta Crystallogr D 65(Pt 5):449-461.
-
(2009)
Acta Crystallogr D
, vol.65
, Issue.PT. 5
, pp. 449-461
-
-
Madauss, K.P.1
-
11
-
-
0037470947
-
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase
-
Zhang H, Yang Z, Shen Y, Tong L (2003) Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science 299:2064-2067.
-
(2003)
Science
, vol.299
, pp. 2064-2067
-
-
Zhang, H.1
Yang, Z.2
Shen, Y.3
Tong, L.4
-
12
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
Horton JD, et al. (2003) Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc Natl Acad Sci USA 100:12027-12032.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
-
13
-
-
3843061127
-
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
-
Chen G, Liang G, Ou J, Goldstein JL, Brown MS (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci USA 101:11245-11250.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11245-11250
-
-
Chen, G.1
Liang, G.2
Ou, J.3
Goldstein, J.L.4
Brown, M.S.5
-
14
-
-
8144229872
-
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
-
Ishii S, Iizuka K, Miller BC, Uyeda K (2004) Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci USA 101:15597-15602.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15597-15602
-
-
Ishii, S.1
Iizuka, K.2
Miller, B.C.3
Uyeda, K.4
-
15
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn BB, Alquier T, Carling D, Hardie DG (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15-25.
-
(2005)
Cell Metab
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
16
-
-
0011057557
-
Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase
-
Witters LA, Watts TD, Daniels DL, Evans JL (1988) Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase. Proc Natl Acad Sci USA 85:5473-5477.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5473-5477
-
-
Witters, L.A.1
Watts, T.D.2
Daniels, D.L.3
Evans, J.L.4
-
17
-
-
77953116832
-
Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
-
Kim CW, et al. (2010) Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis. Proc Natl Acad Sci USA 107:9626-9631.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9626-9631
-
-
Kim, C.W.1
-
18
-
-
0004722664
-
Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level
-
Seelig S, Liaw C, Towle HC, Oppenheimer JH (1981) Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level. Proc Natl Acad Sci USA 78:4733-4737.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 4733-4737
-
-
Seelig, S.1
Liaw, C.2
Towle, H.C.3
Oppenheimer, J.H.4
-
19
-
-
0022367999
-
High basal expression and 3,5,3'-triiodothyronine regulation of messenger ribonucleic acid S14 in lipogenic tissues
-
Jump DB, Oppenheimer JH (1985) High basal expression and 3,5,3'-triiodothyronine regulation of messenger ribonucleic acid S14 in lipogenic tissues. Endocrinology 117:2259-2266.
-
(1985)
Endocrinology
, vol.117
, pp. 2259-2266
-
-
Jump, D.B.1
Oppenheimer, J.H.2
-
20
-
-
0032730324
-
Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription
-
Mater MK, Thelen AP, Pan DA, Jump DB (1999) Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription. J Biol Chem 274:32725-32732.
-
(1999)
J Biol Chem
, vol.274
, pp. 32725-32732
-
-
Mater, M.K.1
Thelen, A.P.2
Pan, D.A.3
Jump, D.B.4
-
21
-
-
15744376705
-
Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes
-
Ma L, Tsatsos NG, Towle HC (2005) Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes. J Biol Chem 280:12019-12027.
-
(2005)
J Biol Chem
, vol.280
, pp. 12019-12027
-
-
Ma, L.1
Tsatsos, N.G.2
Towle, H.C.3
-
22
-
-
0032567445
-
Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
-
Shimomura I, Shimano H, Korn BS, Bashmakov Y, Horton JD (1998) Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver. J Biol Chem 273:35299-35306.
-
(1998)
J Biol Chem
, vol.273
, pp. 35299-35306
-
-
Shimomura, I.1
Shimano, H.2
Korn, B.S.3
Bashmakov, Y.4
Horton, J.D.5
-
23
-
-
23044434394
-
The Spot 14 protein is required for de novo lipid synthesis in the lactating mammary gland
-
Zhu Q, et al. (2005) The Spot 14 protein is required for de novo lipid synthesis in the lactating mammary gland. Endocrinology 146:3343-3350.
-
(2005)
Endocrinology
, vol.146
, pp. 3343-3350
-
-
Zhu, Q.1
-
24
-
-
0034806372
-
Spot 14 gene deletion increases hepatic de novo lipogenesis
-
Zhu Q, et al. (2001) Spot 14 gene deletion increases hepatic de novo lipogenesis. Endocrinology 142:4363-4370.
-
(2001)
Endocrinology
, vol.142
, pp. 4363-4370
-
-
Zhu, Q.1
-
25
-
-
77953175331
-
Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis
-
Aipoalani DL, O'Callaghan BL, Mashek DG, Mariash CN, Towle HC (2010) Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis. Endocrinology 151:2071-2077.
-
(2010)
Endocrinology
, vol.151
, pp. 2071-2077
-
-
Aipoalani, D.L.1
O'Callaghan, B.L.2
Mashek, D.G.3
Mariash, C.N.4
Towle, H.C.5
-
26
-
-
34147119522
-
Human spot 14 protein interacts physically and functionally with the thyroid receptor
-
Chou WY, et al. (2007) Human spot 14 protein interacts physically and functionally with the thyroid receptor. Biochem Biophys Res Commun 357:133-138.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 133-138
-
-
Chou, W.Y.1
-
27
-
-
0030702924
-
Spot 14 protein-protein interactions: Evidence for both homo- and heterodimer formation in vivo
-
Cunningham BA, Maloney M, Kinlaw WB (1997) Spot 14 protein-protein interactions: Evidence for both homo- and heterodimer formation in vivo. Endocrinology 138:5184-5188.
-
(1997)
Endocrinology
, vol.138
, pp. 5184-5188
-
-
Cunningham, B.A.1
Maloney, M.2
Kinlaw, W.B.3
-
28
-
-
0029044299
-
Direct evidence for a role of the "spot 14" protein in the regulation of lipid synthesis
-
Kinlaw WB, Church JL, Harmon J, Mariash CN (1995) Direct evidence for a role of the "spot 14" protein in the regulation of lipid synthesis. J Biol Chem 270:16615-16618.
-
(1995)
J Biol Chem
, vol.270
, pp. 16615-16618
-
-
Kinlaw, W.B.1
Church, J.L.2
Harmon, J.3
Mariash, C.N.4
-
29
-
-
0031045585
-
Preparation of selenomethionyl proteins for phase determination
-
Doublie S (1997) Preparation of selenomethionyl proteins for phase determination. Methods Enzymol 276:523-530.
-
(1997)
Methods Enzymol
, vol.276
, pp. 523-530
-
-
Doublie, S.1
-
30
-
-
0031059866
-
Processing of x-ray diffraction data collected in oscillation mode
-
Otwinowski Z, Minor W (1997) Processing of x-ray diffraction data collected in oscillation mode. Meth Enzymol 276:307-326.
-
(1997)
Meth Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
31
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones TA, Zou JY, Cowan SW, Kjeldgaard M (1991) Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A 47(Pt 2):110-119.
-
(1991)
Acta Crystallogr A
, vol.47
, Issue.PT. 2
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
32
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov GN, Vagin AA, Dodson EJ (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D 53(Pt 3):240-255.
-
(1997)
Acta Crystallogr D
, vol.53
, Issue.PT. 3
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
33
-
-
50149101511
-
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
-
Frank-Kamenetsky M, et al. (2008) Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci USA 105:11915-11920.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11915-11920
-
-
Frank-Kamenetsky, M.1
-
34
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano H, et al. (1996) Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 98:1575-1584.
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
|