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Volumn 107, Issue 49, 2010, Pages 21022-21027

Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation

Author keywords

Aurora kinase; Microtubule organizing center; Protein recruitment

Indexed keywords

AURORA A KINASE; CELL PROTEIN; CENTROSOME PROTEIN; UNCLASSIFIED DRUG;

EID: 78650484299     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014664107     Document Type: Article
Times cited : (89)

References (40)
  • 1
    • 34249336078 scopus 로고    scopus 로고
    • Centrosome biogenesis and function: Centrosomics brings new understanding
    • Bettencourt-Dias M, Glover DM (2007) Centrosome biogenesis and function: Centrosomics brings new understanding. Nat Rev Mol Cell Biol 8:451-463.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 451-463
    • Bettencourt-Dias, M.1    Glover, D.M.2
  • 2
    • 70350771277 scopus 로고    scopus 로고
    • Centrioles, centrosomes, and cilia in health and disease
    • Nigg EA, Raff JW (2009) Centrioles, centrosomes, and cilia in health and disease. Cell 139:663-678.
    • (2009) Cell , vol.139 , pp. 663-678
    • Nigg, E.A.1    Raff, J.W.2
  • 3
    • 38349050936 scopus 로고    scopus 로고
    • The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis
    • Zhu F, et al. (2008) The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol 18:136-141.
    • (2008) Curr Biol , vol.18 , pp. 136-141
    • Zhu, F.1
  • 4
    • 36049016731 scopus 로고    scopus 로고
    • Human Cep192 is required for mitotic centrosome and spindle assembly
    • Gomez-Ferreria MA, et al. (2007) Human Cep192 is required for mitotic centrosome and spindle assembly. Curr Biol 17:1960-1966.
    • (2007) Curr Biol , vol.17 , pp. 1960-1966
    • Gomez-Ferreria, M.A.1
  • 5
    • 3042688773 scopus 로고    scopus 로고
    • The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication
    • Pelletier L, et al. (2004) The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication. Curr Biol 14:863-873.
    • (2004) Curr Biol , vol.14 , pp. 863-873
    • Pelletier, L.1
  • 6
    • 1842583754 scopus 로고    scopus 로고
    • Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2
    • Kemp CA, Kopish KR, Zipperlen P, Ahringer J, O'Connell KF (2004) Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2. Dev Cell 6:511-523.
    • (2004) Dev Cell , vol.6 , pp. 511-523
    • Kemp, C.A.1    Kopish, K.R.2    Zipperlen, P.3    Ahringer, J.4    O'Connell, K.F.5
  • 7
    • 34948901399 scopus 로고    scopus 로고
    • Aurora-A: The maker and breaker of spindle poles
    • Barr AR, Gergely F (2007) Aurora-A: The maker and breaker of spindle poles. J Cell Sci 120:2987-2996.
    • (2007) J Cell Sci , vol.120 , pp. 2987-2996
    • Barr, A.R.1    Gergely, F.2
  • 8
    • 70549105789 scopus 로고    scopus 로고
    • Making the Auroras glow: Regulation of Aurora A and B kinase function by interacting proteins
    • Carmena M, Ruchaud S, Earnshaw WC (2009) Making the Auroras glow: Regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol 21:796-805.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 796-805
    • Carmena, M.1    Ruchaud, S.2    Earnshaw, W.C.3
  • 9
    • 0037180488 scopus 로고    scopus 로고
    • Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
    • Littlepage LE, et al. (2002) Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. Proc Natl Acad Sci USA 99:15440-15445.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15440-15445
    • Littlepage, L.E.1
  • 10
    • 0037446847 scopus 로고    scopus 로고
    • A novel mechanism for activation of the protein kinase Aurora A
    • Eyers PA, Erikson E, Chen LG, Maller JL (2003) A novel mechanism for activation of the protein kinase Aurora A. Curr Biol 13:691-697.
    • (2003) Curr Biol , vol.13 , pp. 691-697
    • Eyers, P.A.1    Erikson, E.2    Chen, L.G.3    Maller, J.L.4
  • 11
    • 0037341906 scopus 로고    scopus 로고
    • A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
    • Tsai MY, et al. (2003) A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 5:242-248.
    • (2003) Nat Cell Biol , vol.5 , pp. 242-248
    • Tsai, M.Y.1
  • 12
    • 0242330123 scopus 로고    scopus 로고
    • Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
    • Bayliss R, Sardon T, Vernos I, Conti E (2003) Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell 12:851-862.
    • (2003) Mol Cell , vol.12 , pp. 851-862
    • Bayliss, R.1    Sardon, T.2    Vernos, I.3    Conti, E.4
  • 13
    • 0037135979 scopus 로고    scopus 로고
    • Human TPX2 is required for targeting Aurora-A kinase to the spindle
    • Kufer TA, et al. (2002) Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158:617-623.
    • (2002) J Cell Biol , vol.158 , pp. 617-623
    • Kufer, T.A.1
  • 14
    • 22944481829 scopus 로고    scopus 로고
    • An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles
    • Ozlü N, et al. (2005) An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. Dev Cell 9:237-248.
    • (2005) Dev Cell , vol.9 , pp. 237-248
    • Ozlü, N.1
  • 15
    • 48249109896 scopus 로고    scopus 로고
    • Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
    • Bird AW, Hyman AA (2008) Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A. J Cell Biol 182:289-300.
    • (2008) J Cell Biol , vol.182 , pp. 289-300
    • Bird, A.W.1    Hyman, A.A.2
  • 16
    • 53549133349 scopus 로고    scopus 로고
    • Dissecting the role of Aurora A during spindle assembly
    • Sardon T, Peset I, Petrova B, Vernos I (2008) Dissecting the role of Aurora A during spindle assembly. EMBO J 27:2567-2579.
    • (2008) EMBO J , vol.27 , pp. 2567-2579
    • Sardon, T.1    Peset, I.2    Petrova, B.3    Vernos, I.4
  • 17
    • 0141429171 scopus 로고    scopus 로고
    • Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
    • Hirota T, et al. (2003) Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 114:585-598.
    • (2003) Cell , vol.114 , pp. 585-598
    • Hirota, T.1
  • 18
    • 26944442735 scopus 로고    scopus 로고
    • The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
    • Zhao ZS, Lim JP, Ng YW, Lim L, Manser E (2005) The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell 20:237-249.
    • (2005) Mol Cell , vol.20 , pp. 237-249
    • Zhao, Z.S.1    Lim, J.P.2    Ng, Y.W.3    Lim, L.4    Manser, E.5
  • 19
    • 77954701718 scopus 로고    scopus 로고
    • Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
    • Molli PR, et al. (2010) Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. J Cell Biol 190:101-114.
    • (2010) J Cell Biol , vol.190 , pp. 101-114
    • Molli, P.R.1
  • 20
    • 34047160952 scopus 로고    scopus 로고
    • A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown
    • Portier N, et al. (2007) A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown. Dev Cell 12:515-529.
    • (2007) Dev Cell , vol.12 , pp. 515-529
    • Portier, N.1
  • 21
    • 0026266161 scopus 로고
    • Cell cycle extracts
    • Murray AW (1991) Cell cycle extracts. Methods Cell Biol 36:581-605.
    • (1991) Methods Cell Biol , vol.36 , pp. 581-605
    • Murray, A.W.1
  • 22
    • 34548835462 scopus 로고    scopus 로고
    • Investigating mitotic spindle assembly and function in vitro using Xenopus laevis egg extracts
    • Hannak E, Heald R (2006) Investigating mitotic spindle assembly and function in vitro using Xenopus laevis egg extracts. Nat Protoc 1:2305-2314.
    • (2006) Nat Protoc , vol.1 , pp. 2305-2314
    • Hannak, E.1    Heald, R.2
  • 23
    • 0141615011 scopus 로고    scopus 로고
    • Long-range communication between chromatin and microtubules in Xenopus egg extracts
    • Carazo-Salas RE, Karsenti E (2003) Long-range communication between chromatin and microtubules in Xenopus egg extracts. Curr Biol 13:1728-1733.
    • (2003) Curr Biol , vol.13 , pp. 1728-1733
    • Carazo-Salas, R.E.1    Karsenti, E.2
  • 24
    • 0029836330 scopus 로고    scopus 로고
    • Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
    • Heald R, et al. (1996) Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature 382:420-425.
    • (1996) Nature , vol.382 , pp. 420-425
    • Heald, R.1
  • 25
    • 17744380396 scopus 로고    scopus 로고
    • Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity
    • Gruss OJ, et al. (2001) Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 104:83-93.
    • (2001) Cell , vol.104 , pp. 83-93
    • Gruss, O.J.1
  • 26
    • 3042734502 scopus 로고    scopus 로고
    • Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition
    • Dutertre S, et al. (2004) Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 117:2523-2531.
    • (2004) J Cell Sci , vol.117 , pp. 2523-2531
    • Dutertre, S.1
  • 27
    • 28444447726 scopus 로고    scopus 로고
    • Aurora A kinase-coated beads function as microtubuleorganizing centers and enhance RanGTP-induced spindle assembly
    • Tsai MY, Zheng Y (2005) Aurora A kinase-coated beads function as microtubuleorganizing centers and enhance RanGTP-induced spindle assembly. Curr Biol 15: 2156-2163.
    • (2005) Curr Biol , vol.15 , pp. 2156-2163
    • Tsai, M.Y.1    Zheng, Y.2
  • 28
    • 33845783921 scopus 로고    scopus 로고
    • Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly
    • Kelly AE, et al. (2007) Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell 12:31-43.
    • (2007) Dev Cell , vol.12 , pp. 31-43
    • Kelly, A.E.1
  • 29
    • 0026764441 scopus 로고
    • Rational design of potent antagonists to the human growth hormone receptor
    • Fuh G, et al. (1992) Rational design of potent antagonists to the human growth hormone receptor. Science 256:1677-1680.
    • (1992) Science , vol.256 , pp. 1677-1680
    • Fuh, G.1
  • 30
    • 0033971720 scopus 로고    scopus 로고
    • Centrosome-independent mitotic spindle formation in vertebrates
    • Khodjakov A, Cole RW, Oakley BR, Rieder CL (2000) Centrosome-independent mitotic spindle formation in vertebrates. Curr Biol 10:59-67.
    • (2000) Curr Biol , vol.10 , pp. 59-67
    • Khodjakov, A.1    Cole, R.W.2    Oakley, B.R.3    Rieder, C.L.4
  • 31
    • 33745255998 scopus 로고    scopus 로고
    • Flies without centrioles
    • Basto R, et al. (2006) Flies without centrioles. Cell 125:1375-1386.
    • (2006) Cell , vol.125 , pp. 1375-1386
    • Basto, R.1
  • 32
    • 0036849137 scopus 로고    scopus 로고
    • Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    • Gruss OJ, et al. (2002) Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nat Cell Biol 4:871-879.
    • (2002) Nat Cell Biol , vol.4 , pp. 871-879
    • Gruss, O.J.1
  • 33
    • 0035090344 scopus 로고    scopus 로고
    • Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly
    • Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E (2001) Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol 3:228-234.
    • (2001) Nat Cell Biol , vol.3 , pp. 228-234
    • Carazo-Salas, R.E.1    Gruss, O.J.2    Mattaj, I.W.3    Karsenti, E.4
  • 34
    • 0033591373 scopus 로고    scopus 로고
    • Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran
    • Wilde A, Zheng Y (1999) Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science 284:1359-1362.
    • (1999) Science , vol.284 , pp. 1359-1362
    • Wilde, A.1    Zheng, Y.2
  • 35
    • 0036241055 scopus 로고    scopus 로고
    • Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
    • Hu CD, Chinenov Y, Kerppola TK (2002) Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell 9:789-798.
    • (2002) Mol Cell , vol.9 , pp. 789-798
    • Hu, C.D.1    Chinenov, Y.2    Kerppola, T.K.3
  • 36
    • 33751539464 scopus 로고    scopus 로고
    • Protein-protein interactions in the allosteric regulation of protein kinases
    • Pellicena P, Kuriyan J (2006) Protein-protein interactions in the allosteric regulation of protein kinases. Curr Opin Struct Biol 16:702-709.
    • (2006) Curr Opin Struct Biol , vol.16 , pp. 702-709
    • Pellicena, P.1    Kuriyan, J.2
  • 37
    • 0035833994 scopus 로고    scopus 로고
    • Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development
    • Joukov V, Chen J, Fox EA, Green JB, Livingston DM (2001) Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development. Proc Natl Acad Sci USA 98:12078-12083.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12078-12083
    • Joukov, V.1    Chen, J.2    Fox, E.A.3    Green, J.B.4    Livingston, D.M.5
  • 38
    • 0032608492 scopus 로고    scopus 로고
    • The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro
    • Desai A, Murray A, Mitchison TJ, Walczak CE (1999) The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol 61:385-412.
    • (1999) Methods Cell Biol , vol.61 , pp. 385-412
    • Desai, A.1    Murray, A.2    Mitchison, T.J.3    Walczak, C.E.4
  • 39
    • 33750434275 scopus 로고    scopus 로고
    • The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly
    • Joukov V, et al. (2006) The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell 127:539-552.
    • (2006) Cell , vol.127 , pp. 539-552
    • Joukov, V.1
  • 40
    • 33646141379 scopus 로고    scopus 로고
    • A novel domain suggests a ciliary function for ASPM, a brain size determining gene
    • Ponting CP (2006) A novel domain suggests a ciliary function for ASPM, a brain size determining gene. Bioinformatics 22:1031-1035.
    • (2006) Bioinformatics , vol.22 , pp. 1031-1035
    • Ponting, C.P.1


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