Stability and membrane orientation of the fukutin transmembrane domain: A combined multiscale molecular dynamics and circular dichroism study

Biochemistry

Volumn 49, Issue 51, 2010, Pages 10796-10802

  Holdbrook, Daniel A ^a   Leung, Yuk Ming ^a   Piggot, Thomas J ^a   Marius, Phedra ^a   Williamson, Philip T F ^a   Khalid, Syma ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BI-LAYER; BILAYER PLANE; BISPHOSPHATES; CIRCULAR DICHROISM; COARSE-GRAINED; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; GOLGI MEMBRANE; HELICAL CONFORMATION; HYDROPHOBIC MISMATCH; MEMBRANE ORIENTATION; MICRO-DOMAINS; MOLECULAR DYNAMICS SIMULATIONS; MULTISCALES; N-TERMINAL DOMAINS; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PREFERENTIAL INTERACTION; PRINCIPAL AXIS; TAIL LENGTH; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS; BIOLOGICAL MEMBRANES; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; LIPIDS; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION;

LIPID BILAYERS;

DIPALMITOYLPHOSPHATIDYLCHOLINE; FUKUTIN; FUKUTIN 1 TRANSMEMBRANE DOMAIN; LIPID; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONFORMATION; GOLGI COMPLEX; HYDROPHOBICITY; LIPID BILAYER; LIPID METABOLISM; MEMBRANE BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION;

AMINO ACID SEQUENCE; CIRCULAR DICHROISM; LIPID BILAYERS; MEMBRANE PROTEINS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLCHOLINES; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 78650479156     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101743w     Document Type: Article

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