Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

European Journal of Immunology

Volumn 41, Issue 1, 2011, Pages 172-181

  Oosting, Marije ^a   Van De Veerdonk, Frank L ^a   Kanneganti, Thirumala Devi ^b   Sturm, Patrick ^a   Verschueren, Ineke ^a   Berende, Anneleen ^a,c   Van Der Meer, Jos W M ^a   Kullberg, Bart Jan ^a   Netea, Mihai G ^a   Joosten, Leo A B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c JEROEN BOSCH HOSPITAL   (Netherlands)

Author keywords

Borrelia; Caspase 1; IL 17

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 33;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BORRELIA BURGDORFERI; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HOST RESISTANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TH1 CELL; TH17 CELL;

ANIMALS; BORRELIA; CASPASE 1; CYTOKINES; INFLAMMASOMES; INTERLEUKIN-17; INTERLEUKIN-1BETA; LYME DISEASE; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 78650390305     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040385     Document Type: Article

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