Bulky DNA adducts in white blood cells: A pooled analysis of 3,600 subjects

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 12, 2010, Pages 3174-3181

  Ricceri, Fulvio ^a,b   Godschalk, Roger W ^c   Peluso, Marco ^d   Phillips, David H ^e   Agudo, Antonio ^f   Georgiadis, Panagiotis ^g   Loft, Steffen ^h   Tjonneland, Anne ⁱ   Raaschou Nielsen, Ole ⁱ   Palli, Domenico ^d   Perera, Frederica ^j   Vermeulen, Roel ^k   Taioli, Emanuela ^l   Sram, Radim J ^m   Munnia, Armelle ^d   Rosa, Fabio ^a   Allione, Alessandra ^a   Matullo, Giuseppe ^a,b   Vineis, Paolo ^a,n  

^a ISI FOUNDATION   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d ISPO Cancer Prevention and Research Institute   (Italy)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^f CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^g INSTITUTE OF BIOLOGY   (Greece)

^h UNIVERSITY OF COPENHAGEN   (Denmark)

ⁱ DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^j Och Spine at New York Presbyterian Hospitals   (United States)

^k UTRECHT UNIVERSITY   (Netherlands)

^l UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^m INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

ⁿ IMPERIAL COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON;

AIR POLLUTANT; AIR POLLUTION; ARTICLE; AUTUMN; BODY MASS; DENMARK; DNA ADDUCT; DNA DAMAGE; EXPOSURE; FEMALE; FRANCE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GREECE; HUMAN; HUMAN CELL; ITALY; LEUKOCYTE; MALE; NETHERLANDS; PRIORITY JOURNAL; SEASONAL VARIATION; SMOKING; SPAIN; SPRING; SUMMER; WINTER;

DNA ADDUCTS; FEMALE; HUMANS; LEUKOCYTES; MALE; SEASONS;

EID: 78650333201     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0314     Document Type: Article

References (51)

1. Phillips DH. DNA adducts as markers of exposure and risk. Mutat Res 2005;577:284-92.
2. Balmain A, Harris CC. Carcinogenesis in mouse and human cells: parallels and paradoxes. Carcinogenesis 2000;21:371-7.
3. Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, Hainaut P. Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 2002;21:7435-51.
4. Peluso M, Ceppi M, Munnia A, Puntoni R, Parodi S. Analysis of 13 (32) P-DNA postlabeling studies on occupational cohorts exposed to air pollution. Am J Epidemiol 2001;153:546-58.
5. Phillips DH. Smoking-related DNA and protein adducts in human tissues. Carcinogenesis 2002;23:1979-2004.
6. Godschalk RW, Feldker DE, Borm PJ, Wouters EF, van Schooten FJ. Body mass index modulates aromatic DNA adduct levels and their persistence in smokers. Cancer Epidemiol Biomarkers Prev 2002;11:790-3.
7. Peluso M, Neri M, Margarino G, Mereu C, Munnia A, Ceppi M, et al. Comparison of DNA adduct levels in nasal mucosa, lymphocytes and bronchial mucosa of cigarette smokers and interaction with metabolic gene polymorphisms. Carcinogenesis 2004;25:2459-65.
8. Peluso M, Airoldi L, Magagnotti C, Fiorini L, Munnia A, Hautefeuille A, et al. White blood cell DNA adducts and fruit and vegetable consumption in bladder cancer. Carcinogenesis 2000;21:183-7.
9. Palli D, Masala G, Vineis P, Garte S, Saieva C, Krogh V, et al. Biomarkers of dietary intake of micronutrients modulate DNA adduct levels in healthy adults. Carcinogenesis 2003;24:739-46.
10. Talaska G, Al-Zoughool M, Malaveille C, Fiorini L, Schumann B, Vietas J, et al. Randomized controlled trial: effects of diet on DNA damage in heavy smokers. Mutagenesis 2006;21:179-83.
11. Sram RJ, Farmer P, Singh R, Garte S, Kalina I, Popov TA, et al. Effect of vitamin levels on biomarkers of exposure and oxidative damage-the EXPAH study. Mutat Res 2009;672:129-34.
12. Peluso M, Munnia A, Hoek G, Krzyzanowski M, Veglia F, Airoldi L, et al. DNA adducts and lung cancer risk: a prospective study. Cancer Res 2005;65:8042-8.
13. Ketelslegers HB, Gottschalk RW, Godschalk RW, Knaapen AM, van Schooten FJ, Vlietinck RF, et al. Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers. Cancer Epidemiol Biomarkers Prev 2006;15:624-9.
14. Palli D, Saieva C, Munnia A, Peluso M, Grechi D, Zanna I, et al. DNA adducts and PM(10) exposure in traffic-exposed workers and urban residents from the EPIC-Florence City study. Sci Total Environ 2008;403:105-12.
15. Kelvin EA, Edwards S, Jedrychowski W, Schleicher RL, Camann D, Tang D, et al. Modulation of the effect of prenatal PAH exposure on PAH-DNA adducts in cord blood by plasma antioxidants. Cancer Epidemiol Biomarkers Prev 2009;18:2262-8.
16. Agudo A, Peluso M, Sala N, Capella G, Munnia A, Piro S, et al. Aromatic DNA adducts and polymorphisms in metabolic genes in healthy adults: findings from the EPIC-Spain cohort. Carcinogenesis 2009;30:968-76.
17. Ibáñez R, Peluso M, Munnia A, Piro S, González C, Amiano P, et al. Aromatic DNA adducts in relation to dietary and other lifestyle factors in Spanish adults. Eur Food Res Technol 2009;229:549-59.
18. Georgiadis P, Topinka J, Stoikidou M, Kaila S, Gioka M, Katsouyanni K, et al. Biomarkers of genotoxicity of air pollution (the AULIS project): bulky DNA adducts in subjects with moderate to low exposures to airborne polycyclic aromatic hydrocarbons and their relationship to environmental tobacco smoke and other parameters. Carcinogenesis 2001;22:1447-57.
19. 32P-postlabelling of aromatic DNA adducts in white blood cells and alveolar macrophages of smokers: saturation at high exposures. Mutat Res 1997;378:65-75.
20. Bak H, Autrup H, Thomsen BL, Tjonneland A, Overvad K, Vogel U, et al. Bulky DNA adducts as risk indicator of lung cancer in a Danish case-cohort study. Int J Cancer 2006;118:1618-22.
21. Peluso M, Airoldi L, Armelle M, Martone T, Coda R, Malaveille C, et al. White blood cell DNA adducts, smoking, and NAT2 and GSTM1 genotypes in bladder cancer: a case-control study. Cancer Epidemiol Biomarkers Prev 1998;7: 341-6.
22. Palli D, Masala G, Peluso M, Gaspari L, Krogh V, Munnia A, et al. The effects of diet on DNA bulky adduct levels are strongly modified by GSTM1 genotype: a study on 634 subjects. Carcinogenesis 2004;25:577-84.
23. Perera FP, Mooney LA, Stampfer M, Phillips DH, Bell DA, Rundle A, et al. Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study. Carcinogenesis 2002;23:1641-6.
24. Tang D, Phillips DH, Stampfer M, Mooney LA, Hsu Y, Cho S, et al. Association between carcinogen-DNA adducts in white blood cells and lung cancer risk in the physicians health study. Cancer Res 2001;61:6708-12.
25. Rossner P Jr, Svecova V, Milcova ALnenickova Z, Solansky I, Santella RM, et al. Oxidative and nitrosative stress markers in bus drivers. Mutat Res 2007;617:23-32.
26. Topinka J, Sevastyanova O, Binkova BChvatalova I, Milcova A, Lnenickova Z, et al. Biomarkers of air pollution exposure - a study of policemen in Prague. Mutat Res 2007;624:9-17. (Pubitemid 47588296)
27. Taioli E, Sram RJ, Binkova B, Kalina I, Popov TA, Garte S, et al. Biomarkers of exposure to carcinogenic PAHs and their relationship with environmental factors. Mutat Res 2007;620:16-21.
28. Singh R, Sram RJ, Binkova B, Kalina I, Popov TA, Georgieva T, et al. The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans. Mutat Res 2007;620:83-92.
29. Castano-Vinyals G, Talaska G, Rothman N, Alguacil J, Garcia-Closas M, Dosemeci M, et al. Bulky DNA adduct formation and risk of bladder cancer. Cancer Epidemiol Biomarkers Prev 2007;16:2155-9.
30. Bonassi S, Ceppi M, Abbandandolo A. Is human exposure to styrene a cause of cytogenetic damage? A re-analysis of the available evidence. Biomarkers 1996;1:217-5.
31. Bonassi S, Znaor A, Ceppi M, Lando C, Chang WP, Holland N, et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 2007;28:625-31.
32. Veglia F, Loft S, Matullo G, Peluso M, Munnia A, Perera F, et al. DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis. Carcinogenesis 2008;29:932-6.
33. Vineis P, Husgafvel-Pursiainen K. Air pollution and cancer: biomarker studies in human populations. Carcinogenesis 2005;26:1846-55.
34. Jakszyn P, Agudo A, Ibanez RGarcia-Closas R, Pera G, Amiano P, et al. Development of a food database of nitrosamines, heterocyclic amines, and polycyclic aromatic hydrocarbons. J Nutr 2004;134:2011-4.
35. Bostrom CE, Gerde P, Hanberg A, Jernstrom B, Johansson C, Kyrklund T, et al. Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Environ Health Perspect 2002;110Suppl3:451-88.
36. Phillips DH. Polycyclic aromatic hydrocarbons in the diet. Mutat Res 1999;443:139-47.
37. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Willett WC, et al. Intake of fat, meat, and fiber in relation to risk of colon cancer in men. Cancer Res 1994;54:2390-7.
38. Probst-Hensch NM, Sinha R, Longnecker MP, Witte JS, Ingles SA, Frankl HD, et al. Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States). Cancer Causes Control 1997;8:175-83.
39. Pfohl-Leszkowicz A, Grosse Y, Carriere V, Cugnenc PH, Berger A, Carnot F, et al. High levels of DNA adducts in human colon are associated with colorectal cancer. Cancer Res 1995;55:5611-6.
40. Scates DK, Venitt S, Phillips RK, Spigelman AD. High pH reduces DNA damage caused by bile from patients with familial adenomatous polyposis: antacids may attenuate duodenal polyposis. Gut 1995;36:918-21.
41. 32P-postlabeling assay for DNA adducts. Nat Protoc 2007;2:2772-81.
42. Phillips DH, Castegnaro M. Standardization and validation of DNA adduct postlabelling methods: report of interlaboratory trials and production of recommended protocols. Mutagenesis 1999;14:301-15.
43. Hazenkamp-von Arx ME, Gotschi Fellmann T, Oglesby L, Ackermann-Liebrich U, Gislason T, Heinrich J, et al. PM2.5 assessment in 21 European study centers of ECRHS II: method and first winter results. J Air Waste Manag Assoc 2003;53:617-28.
44. Shen H, Spitz MR, Qiao Y, Guo Z, Wang LE, Bosken CH, et al. Smoking, DNA repair capacity and risk of nonsmall cell lung cancer. Int J Cancer 2003;107:84-8.
45. Slyskova J, Dusinska M, Kuricova M, Soucek P, Vodickova L, Susova S, et al. Relationship between the capacity to repair 8-oxoguanine, biomarkers of genotoxicity and individual susceptibility in styrene-exposed workers. Mutat Res 2007;634:101-11.
46. Vodicka P, Kumar R, Stetina R, Musak L, Soucek P, Haufroid V, et al. Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant. Environ Mol Mutagen 2004;44:283-92.
47. Lin J, Kadlubar FF, Spitz MR, Zhao H, Wu X. A modified host cell reactivation assay to measure DNA repair capacity for removing 4-aminobiphenyl adducts: a pilot study of bladder cancer. Cancer Epidemiol Biomarkers Prev 2005;14:1832-6.
48. Saha DT, Davidson BJ, Wang A, Pollock AJ, Orden RA, Goldman R, et al. Quantification of DNA repair capacity in whole blood of patients with head and neck cancer and healthy donors by comet assay. Mutat Res 2008;650:55-62.
49. Lampen A, Ebert B, Stumkat L, Jacob J, Seidel A. Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells. Biochim Biophys Acta 2004;1681:38-46.
50. Shimada T. Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab Pharmacokinet 2006;21:257-76.
51. Georgiadis P, Demopoulos NA, Topinka JStephanou G, Stoikidou M, Bekyrou M, et al. Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke. Toxicol Lett 2004;149:269-80.