Military applications of novel hemostatic devices

Expert Review of Medical Devices

Volumn 8, Issue 1, 2011, Pages 41-47

  Gordy, Stephanie D ^a   Rhee, Peter ^b   Schreiber, Martin A ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Combat Gauze ; fibrin sealant dressing; HemCon ; hemorrhage control; hemostatic dressings; military dressings; novel hemostatic agents; QuikClot ; WoundStat

Indexed keywords

FIBRIN SEALANTS; HEMORRHAGE CONTROL; HEMOSTATIC AGENTS; HEMOSTATIC DRESSINGS; MILITARY DRESSINGS;

SEALANTS;

MILITARY APPLICATIONS;

ALGINIC ACID; CHITOSAN; FIBRIN; KAOLIN; SILICON DIOXIDE; SILVER; ZEOLITE; ZINC;

ARTERY INJURY; BATTLE INJURY; BLAST INJURY; BLEEDING; BLOOD CLOTTING; FIRST AID; GAUZE DRESSING; HEMOSTASIS; HUMAN; MILITARY MEDICINE; NONHUMAN; OCCLUSIVE DRESSING; REVIEW; SURVIVAL RATE; WOUND DRESSING; WOUND HEMORRHAGE;

HEMOSTATIC TECHNIQUES; HEMOSTATICS; HUMANS; MILITARY MEDICINE; WOUNDS AND INJURIES;

EID: 78650333071     PISSN: 17434440     EISSN: 17452422     Source Type: Journal    
DOI: 10.1586/erd.10.69     Document Type: Review

References (51)

1. Perkins JG, Cap AP, Weiss BM, et al. Massive transfusion and nonsurgical hemostatic agents. Crit. Care Med. 36, S325-S339 (2008).
2. Bellamy RF. The cause of death in conventional land warfare: implications for combat casualty research. Mil. Med. 149, 59-62 (1984).
3. Dorlac WC, DeBakey ME, Holcomb JB, et al. Mortality from isolated civilian penetrating extremity injury. J. Trauma 59, 217-222 (2005).
4. Hoyt DB, Bulger E, Knudson MM, et al. Death in the operating room: an analysis of a multi-center experience. J. Trauma 37, 426-432 (1994).
5. Champion HR, Bellamy RF, Roberts CP, et al. A profile of combat injury. J. Trauma 54 (Suppl. 5), S13-S19 (2003).
6. Committee on Fluid Resuscitation for Combat Casualties. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Report of the Institute of Medicine. National Academy Press, Washington, DC, USA, 9-18 (1999).
7. Trunkey DD, Slater M. Management of battle casualties. In: Trauma (Fourth Edition). Mattox DV, Feliciano EE, Moore KL (Eds). McGraw-Hill, NY, USA, 1211-1228 (1999).
8. Kelly JF, Ritenour AE, McLaughlin DF, et al. Injury severity and causes of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003-4 versus 2006. J. Trauma 64, S21-S26 (2008).
9. Holcomb J, Caruso J, Wade CE, et al. Causes of death in US Special Operations Forces in the global war on terrorism: 2001-2004. US Army Med. Dep. J. 24-37 (2007).
10. Wedmore I, McManus JG, Pusateri AE, Holcomb JB. A special report on the chitosan-based hemostatic dressing: experience in current combat operations. J. Trauma 60, 655-658 (2006).
11. Cox ED, Schreiber MA, McManus J, et al. New hemostatic agents in the combat setting. Transfusion 49, 244-255 (2009).
12. Ahuja N, Ostomel TA, Rhee P, et al. Testing of modified zeolite hemostatic dressing in a large animal model of lethal groin injury. J. Trauma 61, 1312-1320 (2006).
13. Pusateri AE, Holcomb JB, Kheirabadi BS, et al. Making sense of the preclinical literature on advanced hemostatic products. J. Trauma 60, 674-682 (2006).
14. Trunkey D, Holcomb J. Lessons relearned. Arch. Surg. 143, 112-114 (2008).
15. Rhee P, Brown C, Martin M, et al. QuikClot use in trauma for hemorrhage control: case series of 103 documented uses. J. Trauma 64, 1093-1099 (2008).
16. Rhee P, Holcomb J, Jenkins J. Modern combat casualty care. In: Trauma (Fourth Edition). Mattox DV, Feliciano EE, Moore KL (Eds). McGraw-Hill, NY, USA, 1105-1137 (1999).
17. CordtsPR, Brosch LA, Holcomb JB. Now and then: combat casualty care policies for operation Iraqi freedom and operation enduring freedom compared with those of Vietnam. J. Trauma 64, S14-S20 (2008).
18. Pusateri AE, McCarthey SJ, Gregory KW, et al. Effect of a chitosan-based hemostatic dressing on blood loss and survival in a model of severe venous hemorrhage and hepatic injury in swine. J. Trauma 54, 177-182 (2003).
19. Klokkevold PR, Lew DS, Ellis DG, et al. Effect of chitosan on lingual hemostasis in rabbits. J. Oral Maxillofac. Surg. 49, 858-863 (1991).
20. Rao SB, Sharma CP. Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. J. Biomed. Mater. Res. 34, 21-28 (1997).
21. Thatte HS, Zagarins SE, Amiji M, Khuri SF. Poly-N-acetylglucosamine- mediated red blood cell interactions. J. Trauma 57, S7-S12 (2004).
22. Chou TC, Fu E, Wu CJ, et al. Chitosan enhances platelet adhesion and aggregation. Biochem. Biophys. Res. Commun. 302, 480-483 (2003).
23. Chan MW, Schwaitzberg SD, Demcheva M, et al. Comparison of poly-N-acetyl glucosamine with absorbable collagen and fibrin sealant for achieving hemostasis in a swine model of splenic hemorrhage. J. Trauma 48, 454-458 (2000).
24. Cole, DJ Connolly RJ, Chan MW, et al. A pilot study evaluating the efficacy of a fully acetylated poly-N-acetyl glucosamine membrane formulation of a topical hemostatic agent. Surgery 48, 510-517 (1999).
25. Kheirabadi BS, Acheson EM, Deguzman R, et al. Hemostatic efficacy of two advanced dressings in aortic hemorrhage model in swine. J. Trauma 59, 25-34 (2005).
26. Acheson EM, Kheirabadi BS, Deguzman R, et al. Comparison of hemorrhage control agents applied to lethal extremity arterial hemorrhages in swine. J. Trauma 59, 865-875 (2005).
27. Gustafson SB, Fulkerson P, Bildfell R, et al. Chitosan dressing in swine arterial hemorrhage mode. Prehosp. Emerg. Care 11, 172-178 (2007).
28. Brown MA, Daya MR, Worley JA. Experience with chitosan dressing in a civilian EMS system. J. Emerg. Med. 37, 1-7 (2009).
29. Malmquist JP, Clemens SC, Oien HJ, et al. Hemostasis of oral surgery wounds with HemCon Dental dressing. J. Oral Maxillofac. Surg. 66(6), 1177-1183 (2008).
30. Alam HB, Chen Z, Jaskille A, et al. Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in swine. J. Trauma 56, 974-983 (2004).
31. Kozen BG, Kircher SJ, Henao J, et al. An alternative hemostatic dressing: comparisson of Celox, HemCon, and QuikClot. Acad. Emerg. Med. 15, 74-81 (2008).
32. Arnaud F, Parreno-Sadalan D, Tomori T, et al. Comparison of 10 hemostatic dressings in a groin transection model in swine. J. Trauma 67, 848-855 (2009).
33. Devlin JJ, Kircher S, Kozen BG, et al. Comparison of ChitoFlex, Celox and QuikClot in control of hemorrhage. J. Emer. Med. 1 (2009).
34. Kheirabadi BS, Edens JW, Terrazas IB, et al. Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine. J. Trauma 66, 316-328 (2009).
35. Kheirabadi BS, Sherer MA, Estep JS, et al. Determination of efficacy of new hemostatic dressings in a model of extremity arterial hemorrhage in swine. J. Trauma 67, 450-460 (2009).
36. Alam HB, Burris D, Dacorta JA, et al. Hemorrhage control in the battlefield: role of new hemostatic agents. Military Med. 70, 63-69 (2004).
37. Araunad F, Tomori T, Saito R, et al. Comparative efficacy of granular and bagged formulations of the hemostatic agent QuikClot. J. Trauma 63, 775-782 (2007).
38. Arnaud F, Tomori T, Carr W, et al. Exothermic reaction in zeolite hemostatic dressings: QuikClot ACS and ACS+. Ann. Biomed. Eng. 36(10), 1708-1713 (2008).
39. Carraway JW, Kenta D, Young, K, et al. Comparison of a new mineral based hemostatic agent to a commercially available granular zeolite agent for hemostasis in a swine model of lethal extremity arterial hemorrhage. Resuscitation 78(2), 230-235 (2008).
40. Li J, Yan W, Jing L, et al. Addition of an alginate to a modified zeolite improves hemostatic performance in a swine model of lethal groin injury. J. Trauma 66, 612-620 (2009).
41. Wright FL, Hua HT, Velmahos G, et al. Intracorporeal use of the hemostatic agent QC in a coagulopathic patient with combined thoracoabdominal trauma. J. Trauma 56, 205-208 (2004).
42. Shanmugam V, Robinson MH. Case report of uncontrollable pelvic bleeding-managed by previously unreported method (QuikClot). Colorectal Dis. 11(2), 221-222 (2009).
43. Margulis V, Matsumoto ED, Svatek R, Kabbani W, Cadeddu JA, Lotan Y. Application of novel hemostatic agent during laparoscopic partialnephrectomy. J. Urol. 174(2), 761-764 (2005).
44. Plurad D, Chandrasoma S, Best C, et al. A complication of intracorporeal use of QuikClot for pelvic hemorrhage. J. Trauma 66, 1482-1484 (2009).
45. Sondeen JL, Pusateri AE, Coppes VG, et al. Comparison of 10 different hemostatic dressings in an aortic injury. J. Trauma 54, 280-285 (2003).
46. Delgado AV, Kheirabadi BS, Fruchterman TM, et al. A novel biologic hemostatic dressing (fibrin patch) reduces blood loss and resuscitation volume and improves survival in hypothermic coagulopathic swine with grade v liver injury. J. Trauma 64, 75-80 (2008).
47. Holcomb JB, Pusateri AE, Harris RA, et al. Dry fibrin sealant dressings reduce blood loss, resuscitation volume and improve survival in hypothermic, coagulopathic swine with grade V liver injuries. J. Trauma 47, 233-242 (1999).
48. Kheirabadi BS, Acheson EM, Deguzman R, et al. The potential utility of fibrin sealant dressing in repair of vascular injury in swine. J. Trauma 62, 94-103 (2007).
49. Ward KR, Tiba MH, Holbert WH, et al. Comparison of a new hemostatic agent to current combat hemostatic agents in a swine model of lethal extremity arterial hemorrhage. J. Trauma 63, 276-284 (2007).
50. Kheirabadi BS, Mace JE, Terazzas IB, et al. Safety evaluation of new hemostatic agents, smectite granules, and kaolin-coated gauze in a vascular injury wound model in swine. J. Trauma 68(2), 269-278 (2010).
51. How HemCon Dressings Work. HemCon www.HemCon.com/EducationCenter/ HowHemConDressingsWork.aspx