-
1
-
-
67651158824
-
Role of oxidative stress in alcohol-induced liver injury
-
Cederbaum AI, Lu Y, Wu D. Role of oxidative stress in alcohol-induced liver injury. Arch. Toxicol. 2009; 83: 519-48.
-
(2009)
Arch. Toxicol.
, vol.83
, pp. 519-548
-
-
Cederbaum, A.I.1
Lu, Y.2
Wu, D.3
-
2
-
-
0034831067
-
Nonalcoholic steatohepatitis
-
Reid AE. Nonalcoholic steatohepatitis. Gastroenterology 2001; 121: 710-23.
-
(2001)
Gastroenterology
, vol.121
, pp. 710-723
-
-
Reid, A.E.1
-
3
-
-
38049114951
-
Effects of free radical scavenger on acute liver injury induced by d-galactosamine and lipopolysaccharide in rats
-
Ito K, Ozasa H, Noda Y, Arii S, Horikawa S. Effects of free radical scavenger on acute liver injury induced by d-galactosamine and lipopolysaccharide in rats. Hepatol. Res. 2008; 38: 194-201.
-
(2008)
Hepatol. Res.
, vol.38
, pp. 194-201
-
-
Ito, K.1
Ozasa, H.2
Noda, Y.3
Arii, S.4
Horikawa, S.5
-
4
-
-
0030963238
-
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species
-
Nieminen AL, Byrne AM, Herman B, Lemasters JJ. Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. Am. J. Physiol. 1997; 272: C1286-94.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Nieminen, A.L.1
Byrne, A.M.2
Herman, B.3
Lemasters, J.J.4
-
5
-
-
33644862368
-
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
-
Shen HM, Liu ZG. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic. Biol. Med. 2006; 40: 928-39.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 928-939
-
-
Shen, H.M.1
Liu, Z.G.2
-
6
-
-
47349101596
-
Involvement of JNK regulation in oxidative stress-mediated murine liver injury by microcystin-LR
-
Wei Y, Weng D, Li F et al. Involvement of JNK regulation in oxidative stress-mediated murine liver injury by microcystin-LR. Apoptosis 2008; 13: 1031-42.
-
(2008)
Apoptosis
, vol.13
, pp. 1031-1042
-
-
Wei, Y.1
Weng, D.2
Li, F.3
-
7
-
-
71549172179
-
PI-3-K and AKT: onto the mitochondria
-
Stiles BL. PI-3-K and AKT: onto the mitochondria. Adv. Drug Deliv. Rev. 2009; 61: 1276-82.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 1276-1282
-
-
Stiles, B.L.1
-
8
-
-
0035824526
-
Neuregulin rescues PC12-ErbB4 cells from cell death induced by H(2)O(2). Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase
-
Goldshmit Y, Erlich S, Pinkas-Kramarski R. Neuregulin rescues PC12-ErbB4 cells from cell death induced by H(2)O(2). Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase. J. Biol. Chem. 2001; 276: 46379-85.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46379-46385
-
-
Goldshmit, Y.1
Erlich, S.2
Pinkas-Kramarski, R.3
-
9
-
-
0026751114
-
Epimorphin: a mesenchymal protein essential for epithelial morphogenesis
-
Hirai Y, Takebe K, Takashina M, Kobayashi S, Takeichi M. Epimorphin: a mesenchymal protein essential for epithelial morphogenesis. Cell 1992; 69: 471-81.
-
(1992)
Cell
, vol.69
, pp. 471-481
-
-
Hirai, Y.1
Takebe, K.2
Takashina, M.3
Kobayashi, S.4
Takeichi, M.5
-
10
-
-
0036897340
-
Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis
-
Fritsch C, Swietlicki EA, Lefebvre O et al. Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis. J. Clin. Invest. 2002; 110: 1629-41.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1629-1641
-
-
Fritsch, C.1
Swietlicki, E.A.2
Lefebvre, O.3
-
11
-
-
0031941652
-
Epimorphin functions as a key morphoregulator for mammary epithelial cells
-
Hirai Y, Lochter A, Galosy S, Koshida S, Niwa S, Bissell MJ. Epimorphin functions as a key morphoregulator for mammary epithelial cells. J. Cell Biol. 1998; 140: 159-69.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 159-169
-
-
Hirai, Y.1
Lochter, A.2
Galosy, S.3
Koshida, S.4
Niwa, S.5
Bissell, M.J.6
-
12
-
-
35748981175
-
Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB
-
Miura K, Yoshino R, Hirai Y et al. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. J. Hepatol. 2007; 47: 834-43.
-
(2007)
J. Hepatol.
, vol.47
, pp. 834-843
-
-
Miura, K.1
Yoshino, R.2
Hirai, Y.3
-
13
-
-
33846174242
-
Morphogenic protein epimorphin protects intestinal epithelial cells from oxidative stress by the activation of EGF receptor and MEK/ERK, PI3 kinase/Akt signals
-
Iizuka M, Sasaki K, Hirai Y et al. Morphogenic protein epimorphin protects intestinal epithelial cells from oxidative stress by the activation of EGF receptor and MEK/ERK, PI3 kinase/Akt signals. Am. J. Physiol. Gastrointest. Liver Physiol. 2007; 292: G39-52.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Iizuka, M.1
Sasaki, K.2
Hirai, Y.3
-
14
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol. 1976; 13: 29-83.
-
(1976)
Methods Cell Biol.
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
15
-
-
0035858879
-
Epimorphin mediates mammary luminal morphogenesis through control of C/EBPbeta
-
Hirai Y, Radisky D, Boudreau R et al. Epimorphin mediates mammary luminal morphogenesis through control of C/EBPbeta. J. Cell Biol. 2001; 153: 785-94.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 785-794
-
-
Hirai, Y.1
Radisky, D.2
Boudreau, R.3
-
16
-
-
0026718440
-
A novel cytotoxicity screening assay using a multiwell fluorescence scanner
-
Nieminen AL, Gores GJ, Bond JM, Imberti R, Herman B, Lemasters JJ. A novel cytotoxicity screening assay using a multiwell fluorescence scanner. Toxicol. Appl. Pharmacol. 1992; 115: 147-55.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.115
, pp. 147-155
-
-
Nieminen, A.L.1
Gores, G.J.2
Bond, J.M.3
Imberti, R.4
Herman, B.5
Lemasters, J.J.6
-
17
-
-
0031407680
-
Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes
-
Qian T, Nieminen AL, Herman B, Lemasters JJ. Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes. Am. J. Physiol. 1997; 273.
-
(1997)
Am. J. Physiol.
, pp. 273
-
-
Qian, T.1
Nieminen, A.L.2
Herman, B.3
Lemasters, J.J.4
-
18
-
-
33746073706
-
Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis
-
Han D, Hanawa N, Saberi B, Kaplowitz N. Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis. Free Radic. Biol. Med. 2006; 41: 627-39.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 627-639
-
-
Han, D.1
Hanawa, N.2
Saberi, B.3
Kaplowitz, N.4
-
19
-
-
0026554428
-
Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
-
LeBel CP, Ischiropoulos H, Bondy SC. Evaluation of the probe 2', 7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 1992; 5: 227-31.
-
(1992)
Chem. Res. Toxicol.
, vol.5
, pp. 227-231
-
-
LeBel, C.P.1
Ischiropoulos, H.2
Bondy, S.C.3
-
20
-
-
0032820452
-
Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
-
Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic. Biol. Med. 1999; 27: 612-16.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 612-616
-
-
Wang, H.1
Joseph, J.A.2
-
21
-
-
35648984586
-
N-acetylcysteine attenuates lipopolysaccharide-induced apoptotic liver damage in d-galactosamine-sensitized mice
-
Wang H, Xu DX, Lu JW, Zhao L, Zhang C, Wei W. N-acetylcysteine attenuates lipopolysaccharide-induced apoptotic liver damage in d-galactosamine-sensitized mice. Acta Pharmacol. Sin. 2007; 28: 1803-9.
-
(2007)
Acta Pharmacol. Sin.
, vol.28
, pp. 1803-1809
-
-
Wang, H.1
Xu, D.X.2
Lu, J.W.3
Zhao, L.4
Zhang, C.5
Wei, W.6
-
22
-
-
0033400542
-
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death
-
Lemasters JJ, Qian T, Bradham CA et al. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J. Bioenerg. Biomembr. 1999; 31: 305-19.
-
(1999)
J. Bioenerg. Biomembr.
, vol.31
, pp. 305-319
-
-
Lemasters, J.J.1
Qian, T.2
Bradham, C.A.3
-
23
-
-
34247485841
-
Role of the mitochondrial membrane permeability transition in cell death
-
Tsujimoto Y, Shimizu S. Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 2007; 12: 835-40.
-
(2007)
Apoptosis
, vol.12
, pp. 835-840
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
24
-
-
0012449739
-
Mitogen-activated protein kinase pathways in redox signaling
-
Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front. Biosci. 2003; 8: d369-91.
-
(2003)
Front. Biosci.
, vol.8
-
-
Torres, M.1
-
25
-
-
33750330507
-
Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes
-
Latchoumycandane C, Seah QM, Tan RC, Sattabongkot J, Beerheide W, Boelsterli UA. Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes. Toxicol. Appl. Pharmacol. 2006; 217: 125-33.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.217
, pp. 125-133
-
-
Latchoumycandane, C.1
Seah, Q.M.2
Tan, R.C.3
Sattabongkot, J.4
Beerheide, W.5
Boelsterli, U.A.6
-
26
-
-
33748942862
-
The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting
-
Bogoyevitch MA. The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting. Bioessays 2006; 28: 923-34.
-
(2006)
Bioessays
, vol.28
, pp. 923-934
-
-
Bogoyevitch, M.A.1
-
27
-
-
47949101861
-
Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury
-
Bourdi M, Korrapati MC, Chakraborty M, Yee SB, Pohl LR. Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury. Biochem. Biophys. Res. Commun. 2008; 374: 6-10.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.374
, pp. 6-10
-
-
Bourdi, M.1
Korrapati, M.C.2
Chakraborty, M.3
Yee, S.B.4
Pohl, L.R.5
-
28
-
-
48649104386
-
Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2
-
Theruvath TP, Snoddy MC, Zhong Z, Lemasters JJ. Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation 2008; 85: 1500-4.
-
(2008)
Transplantation
, vol.85
, pp. 1500-1504
-
-
Theruvath, T.P.1
Snoddy, M.C.2
Zhong, Z.3
Lemasters, J.J.4
-
29
-
-
33744956373
-
Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway
-
Wang Y, Singh R, Lefkowitch JH, Rigoli RM, Czaja MJ. Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway. J. Biol. Chem. 2006; 281: 15258-67.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15258-15267
-
-
Wang, Y.1
Singh, R.2
Lefkowitch, J.H.3
Rigoli, R.M.4
Czaja, M.J.5
-
30
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett BL, Sasaki DT, Murray BW et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. USA 2001; 98: 13681-6.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
-
31
-
-
0031772126
-
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release
-
Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, Lemasters JJ. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol. Cell. Biol. 1998; 18: 6353-64.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6353-6364
-
-
Bradham, C.A.1
Qian, T.2
Streetz, K.3
Trautwein, C.4
Brenner, D.A.5
Lemasters, J.J.6
-
32
-
-
60349103901
-
Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase
-
Takeuchi K, Shin-ya T, Nishio K, Ito F. Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase. FEBS J. 2009; 276: 1255-65.
-
(2009)
FEBS J.
, vol.276
, pp. 1255-1265
-
-
Takeuchi, K.1
Shin-ya, T.2
Nishio, K.3
Ito, F.4
|