Effects of free radical scavenger on acute liver injury induced by D-galactosamine and lipopolysaccharide in rats

Hepatology Research

Volumn 38, Issue 2, 2008, Pages 194-201

  Ito, Koji ^a   Ozasa, Hisashi ^b   Noda, Yumi ^a   Arii, Shigeki ^a   Horikawa, Saburo ^c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Minami Ikebukuro Clinic   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Acute hepatic injury; D galactosamine; Edaravone; Fulminant hepatitis; Lipopolysaccharide

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GALACTOSAMINE; HEME OXYGENASE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPEROXIDASE; NORPHENAZONE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

EID: 38049114951     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00252.x     Document Type: Article

References (38)

1. Day HL, Taylor RM. The liver part 5: Acute liver failure. Nurs Times 2005; 102: 26-7.
2. Markov AK, Farias LA, Bennett WS, Subramony C, Mihas AA. Prevention of galactosamine-induced hepatotoxicity in rats with fructose-1,6-diphosphate. Pharmacology 1991; 43: 310-17.
3. Farias LA, Smith EE, Markov AK. Prevention of ischemic-hypoxic brain injury and death in rabbits with fructose-1,6-diphosphate. Stroke 1990; 21: 606-13.
4. Arvelo MB, Cooper JT, Longo C et al. A20 protects mice from d -galactosamine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology 2002; 35: 535-43.
5. Galanos CM, Freudenberg A, Reuter W. Galactosamine-induced sensitization to the lethal effect of endotoxin. Proc Natl Acad Sci USA 1979; 76: 5939-43.
6. Shiratori Y, Kawase T, Shiina S et al. Modulation of hepatotoxicity by macrophages in the liver. Hepatology 1988; 8: 815-21.
7. Sun F, Hamagawa E, Tsutsui C et al. Evaluation of oxidative stress during apoptosis and necrosis caused by d -galactosamine in rat. Biochem Pharmacol 2003; 65: 101-7.
8. Abe K, Yuki S, Kogure K. Strong attenuation of ischemia and postischemic brain edema in rats by a novel free radical scavenger. Stroke 1988; 19: 480-5.
9. Neihorster M, Inoue M, Wendel A. A link between extracellular reactive oxygen and endotoxin-induced release of tumor necrosis factor α in vivo. Biochem Pharmacol 1992; 43: 1151-4.
10. Mayer AMS, Spitzer JA. Modulation of superoxide anion generation by manoalide, arachidonic acid and staurosporine in liver infiltrated neutrophils in a rat model endotoxemia. J Pharmacol Exp Ther 1993; 267: 400-9.
11. Spitzer JA, Mayer AM. Hepatic neutrophil influx: Eicosanoid and superoxide formation in endotoxemia. J Surg Res 1993; 55: 60-7.
12. Watanabe T, Egawa M. Effects of an antistroke agent MCl-186 on cerebralarachidonate cascade. J Pharmacol Exp Ther 1994; 271: 1624-9.
13. Watanabe T, Yuki S, Egawa M, Nishi H. Protective effects of MCI-186 on cerebral ischemia: Possible involvement of free radical scavenging and antioxidant actions. J Pharmacol Exp Ther 1994; 268: 1597-604.
14. Kawai H, Nakai H, Suga M, Yuki S, Watanabe T, Saito K. Effects of a novel free radical scavenger, MCI-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model. J Pharmacol Exp Ther 1997; 281: 921-7.
15. Ito K, Ozasa H, Horikawa S. Effects of prior splenectomy on remnant liver after partial hepatectomy with Pringle maneuver in rats. Live Int 2005; 25: 438-44.
16. Ito K, Ozasa H, Yoneya R, Horikawa S. Splenectomy ameliorates hepatic ischemia and reperfusion injury mediated by heme oxygenase-1 induction in the rat. Liver 2002; 22: 467-73.
17. Palmes D, Skawran S, Spiegel HU. Acute liver failure: From bench to bedside. Transplant Proc 2005; 37: 1628-31.
18. Rahman TM, Hodgson HJ. The effects of early and late administration of inhibitors of inducible nitric oxide synthase in a thioacetamide-induced model of acute hepatic failure in the rat. J Hepatol 2003; 38: 583-90.
19. Ritter C, Reinke A, Andrades M et al. Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. Crit Care Med 2004; 32: 2079-83.
20. Comporti M. Lipid peroxidation and cellular damage in toxic liver injury. Lab Invest 1985; 53: 599-623.
21. Decker K, Keppler D. Galactosamine hepatitis: Key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death. Rev Physiol Biochem Pharmacol 1974; 71: 77-106.
22. Martich GD, Danner RL, Ceska M, Suffredini AF. Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: The effect of anti-inflammatory agents. J Exp Med 1991; 173: 1021-4.
23. Takeuchi S, Goto T, Mikami K et al. Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-alpha production. Hepatol Res 2005; 33: 298-305.
24. Namisaki T, Yoshiji H, Kuriyama S et al. A potent angiogenic factor, vascular endothelial growth factor, improves the survival of the on-going acute hepatic failure in rats. Hepatol Res 2006; 35: 199-203.
25. Leist M, Gantner F, Bohlinger I, Tiegs G, Germann PG, Wendel A. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 1995; 146: 1220-34.
26. Leist M, Gantner F, Jilg S, Wendel A. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol 1995; 154: 1307-16.
27. Gantner F, Uhlig S, Wendel A. Quinine inhibits release of tumor necrosis factor, apoptosis, necrosis and mortality in a murine model of septic liver failure. Eur J Pharmacol 1995; 294: 353-5.
28. Kono H, Asakawa M, Fujii H et al. Edaravone, a novel free radical scavenger, prevents liver injury and mortality in rats administered endotoxin. J Pharmacol Exp Ther 2003; 307: 74-82.
29. Tada S, Nakamoto N, Kameyama K et al. Clinical usefulness of edaravone for acute liver injury. J Gastroenterol Hepatol 2003; 18: 851-7.
30. Nakamoto N, Tada S, Kameyama K et al. A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury. Free Rad Res 2003; 37: 849-59.
31. Iimuro Y, Yamamoto M, Kono H. Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats; analysis of mechanisms of lethality in endotoxemia. J Leukoc Biol 1996; 55: 723-8.
32. Kono H, Yamamoto M, Iimuro Y, Fujii H, Matsumoto Y. The role of splenic macrophages in plasma tumor necrosis factor levels in endotoxemia. Eur Surg Res 1998; 29: 176-86.
33. Feher J, Lengyel G, Blazovics A. Oxidative stress in the liver and biliary tract diseases. Scand J Gastroenterol Suppl 1998; 228: 38-46.
34. Kono H, Fujii H, Matsuda M, Yamamoto M, Matsumoto Y. Gadolinium chloride prevents mortality in hepatectomized rats given endotoxin. J Surg Res 2001; 96: 204-10.
35. Yamamoto T, Yuki S, Watanabe T, Mitsuka M, Saito KI, Kogure K. Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia. Brain Res 1977; 762: 240-2.
36. Kono H, Rusyn I, Uesugi T et al. Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat. Am J Physiol 2001; 280: G1005-12.
37. Ito K, Ozasa H, Horikawa S. Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat. Free Radic Biol Med 2005; 38: 369-74.
38. Tsuji K, Kwon AH, Yoshida H et al. Free radical scavenger (edaravone) prevents endotoxin-induced liver injury after partial hepatectomy in rats. J Hepatol 2005; 42: 94-101.