Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum

Biochemical Journal

Volumn 392, Issue 1, 2005, Pages 117-126

  Tonhosolo, Renata ^a   D'Alexandri, Fabio L ^a   Genta, Fernando A ^a   Wunderlich, Gerhard ^a   Gozzo, Fabio C ^b   Eberlin, Marcos N ^b   Peres, Valnice J ^a   Kimura, Emilia A ^a   Katzin, Alejandro M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antimalarial; Isoprenoid; Malaria; Plasmodium falciparum; Prenyltransferase; Terpene

Indexed keywords

CHOLESTEROL; CLONING; HORMONES; IONIZATION; MASS SPECTROMETRY; PLANTS (BOTANY);

ANTIMALARIAL; ISOPRENOID; MALARIA; PLASMODIUM FALCIPARUM; PRENYLTRANSFERASE; TERPENE;

ENZYMES;

FARNESYL DIPHOSPHATE; ISOPENTENYL DIPHOSPHATE; ISOPRENOID; NEROLIDOL; OCTAPRENYL PYROPHOSPHATE SYNTHASE; POLYCLONAL ANTIBODY; PROTOZOAL PROTEIN; RECOMBINANT ENZYME; RECOMBINANT PROTEIN; SYNTHETASE; TERPENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROSPRAY; ENZYME ANALYSIS; ENZYME SUBSTRATE; ERYTHROCYTE; MICHAELIS CONSTANT; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCHIZONT; TANDEM MASS SPECTROMETRY; THIN LAYER CHROMATOGRAPHY; TROPHOZOITE;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SESQUITERPENES; SUBSTRATE SPECIFICITY;

ANIMALIA; MAMMALIA; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 28044458534     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050441     Document Type: Article

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