Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification

Journal of Biological Chemistry

Volumn 285, Issue 52, 2010, Pages 40956-40964

  Kohli, Rahul M ^a   Maul, Robert W ^b   Guminski, Amy F ^a   McClure, Rhonda L ^b   Gajula, Kiran S ^a   Saribasak, Huseyin ^b   McMahon, Moira A ^a   Siliciano, Robert F ^a   Gearhart, Patricia J ^b   Stivers, James T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY MATURATION; CO-EVOLUTION; CYTIDINE; DRUG RESISTANCE; ENZYME SPECIFICITY; HYPER MUTATION; IMMUNE FUNCTION; IN-VITRO; INNATE DEFENSE; INNATE IMMUNE RESPONSE; LOCAL SEQUENCES; ONCOGENESIS; RETROVIRAL RESTRICTION; SEQUENCE SPECIFICITY;

ANTIBODIES; CATALYSTS; DNA SEQUENCES; GRAFTING (CHEMICAL); NUCLEIC ACIDS; ONCOGENIC VIRUSES; SCAFFOLDS;

ENZYMES;

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; IMMUNOGLOBULIN;

ADAPTIVE IMMUNITY; ANTIBODY SPECIFICITY; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; ENZYME SPECIFICITY; FLOW CYTOMETRY; GENE LOCUS; GENETIC VARIABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INNATE IMMUNITY; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; SOMATIC HYPERMUTATION; VIRION;

AMINO ACID MOTIFS; ANIMALS; ANTIBODIES, VIRAL; B-LYMPHOCYTES; CYTIDINE DEAMINASE; EVOLUTION, MOLECULAR; HEK293 CELLS; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, INNATE; MICE; MICE, KNOCKOUT; PROTEIN STRUCTURE, SECONDARY;

EID: 78650307603     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.177402     Document Type: Article

References (53)

1. Harris, R. S., Bishop, K. N., Sheehy, A. M., Craig, H. M., Petersen-Mahrt, S. K., Watt, I. N., Neuberger, M. S., and Malim, M. H. (2003) Cell 113, 803-809
2. Yu, Q., König, R., Pillai, S., Chiles, K., Kearney, M., Palmer, S., Richman, D., Coffin, J. M., and Landau, N. R. (2004) Nat. Struct. Mol. Biol. 11, 435-442
3. Browne, E. P., Allers, C., and Landau, N. R. (2009) Virology 387, 313-321
4. Navarro, F., Bollman, B., Chen, H., König, R., Yu, Q., Chiles, K., and Landau, N. R. (2005) Virology 333, 374-386
5. Schumacher, A. J., Haché, G., Macduff, D. A., Brown, W. L., and Harris, R. S. (2008) J. Virol. 82, 2652-2660
6. Miyagi, E., Opi, S., Takeuchi, H., Khan, M., Goila-Gaur, R., Kao, S., and Strebel, K. (2007) J. Virol. 81, 13346-13353
7. Sheehy, A. M., Gaddis, N. C., Choi, J. D., and Malim, M. H. (2002) Nature 418, 646-650
8. Yu, X., Yu, Y., Liu, B., Luo, K., Kong, W., Mao, P., and Yu, X. F. (2003) Science 302, 1056-1060
9. Revy, P., Muto, T., Levy, Y., Geissmann, F., Plebani, A., Sanal, O., Catalan, N., Forveille, M., Dufourcq-Labelouse, R., Gennery, A., Tezcan, I., Ersoy, F., Kayserili, H., Ugazio, A. G., Brousse, N., Muramatsu, M., Notarangelo, L. D., Kinoshita, K., Honjo, T., Fischer, A., and Durandy, A. (2000) Cell 102, 565-575
10. Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., and Honjo, T. (2000) Cell 102, 553-563
11. Odegard, V. H., and Schatz, D. G. (2006) Nat. Rev. Immunol. 6, 573-583
12. Sadler, H. A., Stenglein, M. D., Harris, R. S., and Mansky, L. M. (2010) J. Virol. 84, 7396-7404
13. Kim, E. Y., Bhattacharya, T., Kunstman, K., Swantek, P., Koning, F. A., Malim, M. H., and Wolinsky, S. M. (2010) J. Virol. 84, 10402-10405
14. Mulder, L. C., Harari, A., and Simon, V. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 5501-5506
15. Okazaki, I. M., Kotani, A., and Honjo, T. (2007) Adv. Immunol. 94, 245-273
16. Ramiro, A. R., Jankovic, M., Eisenreich, T., Difilippantonio, S., Chen- Kiang, S., Muramatsu, M., Honjo, T., Nussenzweig, A., and Nussenzweig, M. C. (2004) Cell 118, 431-438
17. Huthoff, H., Autore, F., Gallois-Montbrun, S., Fraternali, F., and Malim, M. H. (2009) PLoS Pathog. 5, e1000330
18. Bogerd, H. P., and Cullen, B. R. (2008) RNA 14, 1228-1236
19. Liddament, M. T., Brown, W. L., Schumacher, A. J., and Harris, R. S. (2004) Curr. Biol. 14, 1385-1391
20. Bransteitter, R., Pham, P., Calabrese, P., and Goodman, M. F. (2004) J. Biol. Chem. 279, 51612-51621
21. Armitage, A. E., Katzourakis, A., de Oliveira, T., Welch, J. J., Belshaw, R., Bishop, K. N., Kramer, B., McMichael, A. J., Rambaut, A., and Iversen, A. K. (2008) J. Virol. 82, 8743-8761
22. Hackney, J. A., Misaghi, S., Senger, K., Garris, C., Sun, Y., Lorenzo, M. N., and Zarrin, A. A. (2009) Adv. Immunol. 101, 163-189
23. Haché, G., Liddament, M. T., and Harris, R. S. (2005) J. Biol. Chem. 280, 10920-10924
24. Langlois, M. A., Beale, R. C., Conticello, S. G., and Neuberger, M. S. (2005) Nucleic Acids Res. 33, 1913-1923
25. Holden, L. G., Prochnow, C., Chang, Y. P., Bransteitter, R., Chelico, L., Sen, U., Stevens, R. C., Goodman, M. F., and Chen, X. S. (2008) Nature 456, 121-124
26. Conticello, S. G., Langlois, M. A., and Neuberger, M. S. (2007) Nat. Struct. Mol. Biol. 14, 7-9
27. Kohli, R. M., Abrams, S. R., Gajula, K. S., Maul, R. W., Gearhart, P. J., and Stivers, J. T. (2009) J. Biol. Chem. 284, 22898-22904
28. Carpenter, M. A., Rajagurubandara, E., Wijesinghe, P., and Bhagwat, A. S. (2010) DNA Repair 9, 579-587
29. Wang, M., Rada, C., and Neuberger, M. S. (2010) J. Exp. Med. 207, 141-153
30. Zheng, Y. H., Irwin, D., Kurosu, T., Tokunaga, K., Sata, T., and Peterlin, B. M. (2004) J. Virol. 78, 6073-6076
31. Fugmann, S. D., Rush, J. S., and Schatz, D. G. (2004) Eur. J. Immunol. 34, 844-849
32. Opi, S., Kao, S., Goila-Gaur, R., Khan, M. A., Miyagi, E., Takeuchi, H., and Strebel, K. (2007) J. Virol. 81, 8236-8246
33. Zhang, H., Zhou, Y., Alcock, C., Kiefer, T., Monie, D., Siliciano, J., Li, Q., Pham, P., Cofrancesco, J., Persaud, D., and Siliciano, R. F. (2004) J. Virol. 78, 1718-1729
34. Fouchier, R. A., Meyer, B. E., Simon, J. H., Fischer, U., and Malim, M. H. (1997) EMBO J. 16, 4531-4539
35. Simon, J. H., Fouchier, R. A., Southerling, T. E., Guerra, C. B., Grant, C. K., and Malim, M. H. (1997) J. Virol. 71, 5259-5267
36. Butler, S. L., Hansen, M. S., and Bushman, F. D. (2001) Nat. Med. 7, 631-634
37. Crooks, G. E., Hon, G., Chandonia, J. M., and Brenner, S. E. (2004) Genome Res. 14, 1188-1190
38. Rajagopal, D., Maul, R. W., Ghosh, A., Chakraborty, T., Khamlichi, A. A., Sen, R., and Gearhart, P. J. (2009) J. Exp. Med. 206, 1237-1244
39. Russell, R. A., Moore, M. D., Hu, W. S., and Pathak, V. K. (2009) Retrovirology 6, 16
40. Langlois, M. A., and Neuberger, M. S. (2008) J. Virol. 82, 4660-4664
41. Mbisa, J. L., Bu, W., and Pathak, V. K. (2010) J. Virol. 84, 5250-5259
42. Saribasak, H., Saribasak, N. N., Ipek, F. M., Ellwart, J. W., Arakawa, H., and Buerstedde, J. M. (2006) J. Immunol. 176, 365-371
43. Wang, M., Yang, Z., Rada, C., and Neuberger, M. S. (2009) Nat. Struct. Mol. Biol. 16, 769-776
44. Roy, D., Yu, K., and Lieber, M. R. (2008) Mol. Cell. Biol. 28, 50-60
45. Yu, K., Chedin, F., Hsieh, C. L., Wilson, T. E., and Lieber, M. R. (2003) Nat. Immunol. 4, 442-451
46. Chen, K. M., Harjes, E., Gross, P. J., Fahmy, A., Lu, Y., Shindo, K., Harris, R. S., and Matsuo, H. (2008) Nature 452, 116-119
47. Rausch, J. W., Chelico, L., Goodman, M. F., and Le Grice, S. F. (2009) J. Biol. Chem. 284, 7047-7058
48. Goila-Gaur, R., Khan, M. A., Miyagi, E., Kao, S., and Strebel, K. (2007) Retrovirology 4, 61
49. Bulliard, Y., Turelli, P., Röhrig, U. F., Zoete, V., Mangeat, B., Michielin, O., and Trono, D. (2009) J. Virol. 83, 12611-12621
50. Smith, R. A., Loeb, L. A., and Preston, B. D. (2005) Virus Res. 107, 215-228
51. Zhang, J., and Webb, D. M. (2004) Hum. Mol. Genet. 13, 1785-1791
52. Berkhout, B., Grigoriev, A., Bakker, M., and Lukashov, V. V. (2002) AIDS Res. Hum. Retroviruses 18, 133-141
53. Wagner, S. D., Milstein, C., and Neuberger, M. S. (1995) Nature 376, 732