NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 1, 2011, Pages 121-129

  Riley, Maurisa F ^a   McBride, Kim L ^b,c   Cole, Susan E ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Bicuspid aortic valve; Epithelial to mesenchymal transition (EMT); Left ventricular outflow tract; Notch signaling

Indexed keywords

NOTCH1 RECEPTOR;

ALLELE; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EPITHELIAL MESENCHYMAL TRANSITION; HEART LEFT VENTRICLE OUTFLOW TRACT; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ACTINS; ANIMALS; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CELL LINE; CELL MEMBRANE; COCULTURE TECHNIQUES; ENDOPLASMIC RETICULUM; EPITHELIAL-MESENCHYMAL TRANSITION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MUSCLE, SMOOTH; MUTATION, MISSENSE; NIH 3T3 CELLS; RATS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; TRANSFECTION; VENTRICULAR OUTFLOW OBSTRUCTION;

GASTROPODA;

EID: 78650262134     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.10.002     Document Type: Article

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