The tetralogy of fallot-associated G274D mutation impairs folding of the second epidermal growth factor repeat in Jagged-1

FEBS Journal

Volumn 276, Issue 21, 2009, Pages 6247-6257

  Guarnaccia, Corrado ^a   Dhir, Somdutta ^a   Pintar, Alessandro ^a   Pongor, Sándor ^a  

^a AREA Science Park   (Italy)

Author keywords

Alagille syndrome; Disease mutation; Limited proteolysis; Notch signaling; Oxidative folding

Indexed keywords

EPIDERMAL GROWTH FACTOR; JAGGED1; NOTCH RECEPTOR; PEPTIDE DERIVATIVE;

ALAGILLE SYNDROME; AMINO ACID SUBSTITUTION; ARTICLE; CELL FATE; CORRELATION ANALYSIS; FALLOT TETRALOGY; GENE MUTATION; HUMAN; LIGAND BINDING; PHENOTYPE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; WILD TYPE;

ALAGILLE SYNDROME; AMINO ACID SEQUENCE; ANIMALS; CALCIUM-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; PROTEIN FOLDING; TANDEM REPEAT SEQUENCES; TETRALOGY OF FALLOT;

METAZOA;

EID: 70349952137     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07333.x     Document Type: Article

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