Multiscale Coculture Models for Orthopedic Interface Tissue Engineering

Biomedical Nanostructures

Volumn , Issue , 2007, Pages 357-373

  Lu, Helen H ^a,b   Wang, I Ning E ^a  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Biomimetic coculture models; Ligament reconstruction surgery; Soft tissue to bone interface

Indexed keywords

EID: 78650257252     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470185834.ch14     Document Type: Chapter

References (84)

1. Bhatia SN, Balis UJ, Yarmush ML, Toner M. Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells. FASEB J 1999;13:1883-1900.
2. Lu HH and Jiang J. Interface tissue engineering and the formulation of multipletissue systems. Adv Biochem Eng Biotechnol 2006;102:91-111.
3. Mikos AG, et al. Engineering complex tissues. Tissue Eng 2006;12:3307-3339.
4. Cooper RR and Misol S. Tendon and ligament insertion: a light and electron microscopic study. J Bone Joint Surg Am 1970;52:1-20.
5. Benjamin M, Evans EJ, Copp L. The histology of tendon attachments to bone in man. J Anat 1986;149:89-100.
6. Niyibizi C, Visconti CS, Kavalkovich K, Woo SL. Collagens in an adult bovine medial collateral ligament: immunofluorescence localization by confocal microscopy reveals that type XIV collagen predominates at the ligament-bone junction. Matrix Biol 1995;14:743-751.
7. Wei X and Messner K. The postnatal development of the insertions of the medial collateral ligament in the rat knee. Anat Embryol (Berl) 1996;193:53-59.
8. Petersen W and Tillmann B. Structure and vascularization of the cruciate ligaments of the human knee joint. Anat Embryol (Berl) 1999;200:325-334.
9. Thomopoulos S, Williams GR, Gimbel JA, Favata M, Soslowsky LJ. Variations of biomechanical, structural, and compositional properties along the tendon to bone insertion site. J Orthop Res 2003;21:413-419.
10. Wang IN, Mitroo S, Chen FH, Lu HH, Doty SB. Age-dependent changes in matrix composition and organization at the ligament-to-bone insertion. J Orthop Res 2006;24:1745-1755.
11. Niyibizi C, Sagarrigo VC, Gibson G, Kavalkovich K. Identification and immunolocalization of type X collagen at the ligament-bone interface. Biochem Biophys Res Commun 1996;222:584-589.
12. Woo SL and Buckwalter JA. AAOS/NIH/ORS workshop. Injury and repair of the musculoskeletal soft tissues. Savannah, Georgia, June 18-20, 1987. J Orthop Res 1988;6:907-931.
13. Friedman MJ, et al. Autogeneic anterior cruciate ligament (ACL) anterior reconstruction of the knee: a review. Clin Orthop: 1985;9-14.
14. Kurosaka M, Yoshiya S, Andrish JT. A biomechanical comparison of different surgical techniques of graft fixation in anterior cruciate ligament reconstruction. Am J Sports Med 1987;15:225-229.
15. Robertson DB, Daniel DM, Biden E. Soft tissue fixation to bone. Am J Sports Med 1986;14:398-403.
16. Yahia L. Ligaments and Ligamentoplasties. Springer Verlag; Berlin Heidelberg: 1997.
17. Blickenstaff KR, Grana WA, Egle D. Analysis of a semitendinosus autograft in a rabbit model. Am J Sports Med 1997;25:554-559.
18. Yoshiya S,Nagano M,Kurosaka M, Muratsu H, Mizuno K. Graft healing in the bone tunnel in anterior cruciate ligament reconstruction. Clin Orthop 2000;278-286.
19. Eriksson K, Kindblom LG, Wredmark T. Semitendinosus tendon graft ingrowth in tibial tunnel following ACL reconstruction: a histological study of 2 patients with different types of early graft failure. Acta Orthop Scand 2000;71:275-279.
20. Rodeo SA, Arnoczky SP, Torzilli PA, Hidaka C, Warren RF. Tendon-healing in a bone tunnel: a biomechanical and histological study in the dog. J Bone Joint Surg Am 1993;75:1795-1803.
21. Jiang J, Nicoll SB, Lu HH. Co-culture of osteoblasts and chondrocytes modulates cellular differentiation in vitro. Biochem Biophys Res Commun 2005;338:762-770.
22. Wang IE, et al. Role of osteoblast-fibroblast interactions in the regeneration of the ligament-to-bone interface. J Orthop Res 2007. (in press).
23. Tsai J, Wang IE, Kam LC, Lu HH. Novel micropatterned microfluidic system for osteoblast and fibroblast co-culture. Trans Soc Biomate 2005, p. 30.
24. Guguen-Guillouzo C, et al. Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. Exp Cell Res 1983;143:47-54.
25. Langenbach R, et al. Maintenance of adult rat hepatocytes on C3H/10T1/2 cells. Cancer Res 1979;39:3509-3514.
26. Shimaoka S, Nakamura T, Ichihara A. Stimulation of growth of primary cultured adult rat hepatocytes without growth factors by coculture with nonparenchymal liver cells,. Exp Cell Res 1987;172:228-242.
27. Ogiso B, Hughes FJ, Melcher AH, McCulloch CA. Fibroblasts inhibit mineralised bone nodule formation by rat bone marrow stromal cells in vitro. J Cell Physiol 1991;146:442-450.
28. Nevo Z, et al. Adhesion characteristics of chondrocytes cultured separately and in co-cultures with synovial fibroblasts. Cell Biol Int 1993;17:255-273.
29. Nakamata T, et al. In vitro demonstration of cell-to-cell interaction in growth plate cartilage using chondrocytes established from p53-/-mice. J Bone Miner Res 2003;18:97-107.
30. Shimoaka T, et al. Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF-10. J Biol Chem 2002;277:7493-7500.
31. Jiang J, Leong NL, Mung J, Hidaka C, Lu HH. Interaction between zonal populations of articular chondrocytes suppresses chondrocyte mineralization and this process is mediated by PTHrP. Osteoarthritis and Cartilage. (in Press).
32. D'andrea P, Calabrese A, Grandolfo M. Intercellular calcium signalling between chondrocytes and synovial cells in co-culture. Biochem J 1998;329(Pt 3):681-687.
33. Gerstenfeld LC, et al. Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells. J Bone Miner Res 2002;17:221-230.
34. Gerstenfeld LC, Barnes GL, Shea CM, Einhorn TA. Osteogenic differentiation is selectively promoted by morphogenetic signals from chondrocytes and synergized by a nutrient rich growth environment. Connect Tissue Res 2003;44 (1 Suppl): 85-91.
35. Lacombe-Gleize S, Gregoire M, Demignot S, Hecquet C, Adolphe M. Implication of TGF beta 1 in co-culture of chondrocytes-osteoblasts. In Vitro Cell Dev Biol Anim 1995;31:649-652.
36. Sanchez C, et al. Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes. Osteoarthritis Cartilage 2005;13:988-997.
37. Kinto N, et al. Fibroblasts expressing sonic hedgehog induce osteoblast differentiation and ectopic bone formation. FEBS Lett 1997;404:319-323.
38. Spector JA, et al. Co-culture of osteoblasts with immature dural cells causes an increased rate and degree of osteoblast differentiation. Plas Reconstr Surg 2002;109:631-642.
39. Fillinger MF, O'Connor SE, Wagner RJ, Cronenwett JL. The effect of endothelial cell coculture on smooth muscle cell proliferation. J Vasc Surg 1993;17: 1058-1067.
40. Burch MG, Pepe GJ, Dobrian AD, Lattanzio FA, Jr., Albrecht ED. Development of a coculture system and use of confocal laser fluorescent microscopy to study human microvascular endothelial cell and mural cell interaction. Microvasc Res 2005;70:43-52.
41. Sakai H, et al. Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells. Ann Rheum Dis 2002;61:103-109.
42. Shan JM, Wang IE, Lu HH. Osteoblast-fibroblast interactions modulate cell phenotypes through paracrine and autocrine regulations. Trans Orthop Res Soc 2007.
43. Sun WS, Moffat KL, Lu HH. Characterization of fibrochondrocytes derived from the ligament-bone insertion. Trans Orthop Res Soc 2007.
44. Wang IE and Lu HH. Triculture of bovine anterior cruciate ligament fibroblasts, osteoblasts and chondrocytes with application in interface tissue engineering. Trans Orthop Res Soc 2005.
45. Wang IE, Mitroo S, Poli R, Sun WS, Lu HH. Fibroblast and osteoblast interactions modulate the potential of bone marrow stromal cells to differentiation into fibrochondrocyte-like cells. Trans Orthop Res Soc 2007. (53rd meeting).
46. Bhatia SN, Yarmush ML, Toner M. Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts. J Biomed Mater Res 1997;34: 189-199.
47. Bhatia SN, Balis UJ, Yarmush ML, Toner M. Microfabrication of hepatocyte/ fibroblast co-cultures: role of homotypic cell interactions. Biotechnol Prog 1998;14: 378-387.
48. Yamato M, Konno C, Utsumi M, Kikuchi A, Okano T. Thermally responsive polymer-grafted surfaces facilitate patterned cell seeding and co-culture. Biomaterials 2002;23:561-567.
49. Khademhosseini A, et al. Layer-by-layer deposition of hyaluronic acid and poly-Llysine for patterned cell co-cultures. Biomaterials 2004;25:3583-3592.
50. Whitesides GM, Ostuni E, Takayama S, Jiang X, Ingber DE. Soft lithography in biology and biochemistry. Ann Rev Biomed Eng 2001;3:335-373.
51. Albrecht DR, Tsang VL, Sah RL, Bhatia SN. Photo- and Electropatterning of Hydrogel-Encapsulated Living Cell Arrays. Lab Chip 2005;5(1):111-118.
52. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Geometric control of cell life and death. Science 1997;276:1425-1428.
53. Cukierman E, Pankov R, Stevens DR, Yamada KM. Taking cell-matrix adhesions to the third dimension. Science 2001;294:1708-12.
54. Spalazzi JP, Doty SB, Moffat KL, Levine WN, Lu HH. Development of controlled matrix heterogeneity on a triphasic scaffold orthopedic interface tissue engineering. Tissue Eng 2006;12:3497-3508.
55. Takeichi M. Morphogenetic roles of classic cadherins. Curr Opin Cell Biol 1995;7:619-627.
56. Price SR, De Marco Garcia NV, Ranscht B, Jessell TM. Regulation of motor neuron pool sorting by differential expression of type II cadherins. Cell 2002;109:205-216.
57. Keller R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science 2002;298:1950-1954.
58. Zhong Y, Brieher WM, Gumbiner BM. Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody. J Cell Biol 1999;144:351-359
59. Hay ED and Zuk A. Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am J Kidney Dis 1995;26:678-690.
60. Cano A, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000;2:76-83.
61. Leckband D and Prakasam A. Mechanism and dynamics of cadherin adhesion. Ann Rev Biomed Eng 2006;8:259-287.
62. Kim SH, Jen WC, De Robertis EM, Kintner C. The protocadherin PAPC establishes segmental boundaries during somitogenesis in xenopus embryos. Curr Biol 2000;10:821-830.
63. Tepass U, Godt D, Winklbauer R. Cell sorting in animal development: signalling and adhesive mechanisms in the formation of tissue boundaries. Curr Opin Genet Dev 2002;12:572-582.
64. Hermiston ML, Wong MH, Gordon JI. Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev 1996;10:985-996.
65. Tinkle CL, Lechler T, Pasolli HA, Fuchs E. Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci USA 2004;101:552-557.
66. Kobielak A and Fuchs E. Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. Nat Rev Mol Cell Biol 2004;5:614-625.
67. Stains JP and Civitelli R. Cell-cell interactions in regulating osteogenesis and osteoblast function. Birth Defects Res C Embryo Today 2005;75:72-80.
68. Berx G, Nollet F, van RF. Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. Cell Adhes Commun 1998;6:171-184.
69. Kiener HP and Brenner MB. Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion. Arthritis Res Ther 2005;7:49-54.
70. Ferrari SL, et al. A role for N-cadherin in the development of the differentiated osteoblastic phenotype. J Bone Miner Res 2000;15:198-208.
71. Marie PJ. Role of N-cadherin in bone formation. J Cell Physiol 2002;190:297-305.
72. Stains JP and Civitelli R. Cell-to-cell interactions in bone. Biochem Biophys Res Commun 2005;328:721-727.
73. Lin WL, Chien HH, Cho MI. N-cadherin expression during periodontal ligament cell differentiation in vitro. J Periodontol 1999;70:1039-1045.
74. Castro CH, et al. Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis. J Cell Sci 2004;117:2853-2864.
75. Siliciano JD and Goodenough DA. Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells. J Cell Biol 1988;107:2389-2399.
76. Troxell ML, et al. Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly. J Cell Sci 2000;113(Pt 6): 985-996.
77. Oberlender SA and Tuan RS. Spatiotemporal profile of N-cadherin expression in the developing limb mesenchyme. Cell Adhes Commun 1994;2:521-537.
78. Oberlender SA and Tuan RS. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 1994;120:177-187.
79. DeLise AM, Fischer L, Tuan RS. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 2000;8:309-334.
80. Tavella S, Raffo P, Tacchetti C, Cancedda R, Castagnola P. N-CAM and Ncadherin expression during in vitro chondrogenesis. Exp Cell Res 1994;215: 354-362.
81. Chuong CM, et al. Roles of adhesion molecules NCAM and tenascin in limb skeletogenesis: analysis with antibody perturbation, exogenous gene expression, talpid mutants and activin stimulation. Prog Clin Biol Res 1993;383B:465-474.
82. Kii I, Amizuka N, Shimomura J, Saga Y, Kudo A. Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage. J Bone Miner Res 2004;19: 1840-1849.
83. McNeilly CM, Banes AJ, Benjamin M, Ralphs JR. Tendon cells in vivo form a three dimensional network of cell processes linked by gap junctions. J Anat 1996;189(Pt 3): 593-600.
84. Ralphs JR, Waggett AD, Benjamin M. Actin stress fibres and cell-cell adhesion molecules in tendons: organisation in vivo and response to mechanical loading of tendon cells in vitro. Matrix Biol 2002;21:67-74.