-
2
-
-
0033105864
-
+ channel by Nedd4 in Liddle's syndrome
-
+ channel by Nedd4 in Liddle's syndrome. J Clin Invest 103:667-673
-
(1999)
J Clin Invest
, vol.103
, pp. 667-673
-
-
Abriel, H.1
Loffing, J.2
Rebhun, J.F.3
Pratt, J.H.4
Schild, L.5
Horisberger, J.D.6
Rotin, D.7
Staub, O.8
-
3
-
-
0033621468
-
The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes
-
Alvarez de la Rosa D, Zhang P, Naray-Fejes-Toth A, Fejes-Toth G, Canessa CM (1999) The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. J Biol Chem 274: 37834-37839
-
(1999)
J Biol Chem
, vol.274
, pp. 37834-37839
-
-
Alvarez De La Rosa, D.1
Zhang, P.2
Naray-Fejes-Toth, A.3
Fejes-Toth, G.4
Canessa, C.M.5
-
4
-
-
42049103429
-
Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARgamma agonist pioglitazone
-
Artunc F, Sandulache D, Nasir O, Boini KM, Friedrich B, Beier N, Dicks E, Potzsch S, Klingel K, Amann K, Blazer-Yost BL, Scholz W, Risler T, Kuhl D, Lang F (2008) Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARgamma agonist pioglitazone. Pflugers Arch 456:425-436
-
(2008)
Pflugers Arch
, vol.456
, pp. 425-436
-
-
Artunc, F.1
Sandulache, D.2
Nasir, O.3
Boini, K.M.4
Friedrich, B.5
Beier, N.6
Dicks, E.7
Potzsch, S.8
Klingel, K.9
Amann, K.10
Blazer-Yost, B.L.11
Scholz, W.12
Risler, T.13
Kuhl, D.14
Lang, F.15
-
5
-
-
33750351417
-
Regulation of NaCl transport in the renal collecting duct: Lessons from cultured cells
-
Bens M, Chassin C, Vandewalle A (2006) Regulation of NaCl transport in the renal collecting duct: Lessons from cultured cells. Pflugers Arch 453:133-146
-
(2006)
Pflugers Arch
, vol.453
, pp. 133-146
-
-
Bens, M.1
Chassin, C.2
Vandewalle, A.3
-
6
-
-
0027483065
-
Epithelial sodium channel related to proteins involved in neurodegeneration
-
Canessa CM, Horisberger JD, Rossier BC (1993) Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361:467-470
-
(1993)
Nature
, vol.361
, pp. 467-470
-
-
Canessa, C.M.1
Horisberger, J.D.2
Rossier, B.C.3
-
8
-
-
0031930649
-
Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes
-
Chraibi A, Vallet V, Firsov D, Hess SK, Horisberger JD (1998) Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes. J Gen Physiol 111: 127-138
-
(1998)
J Gen Physiol
, vol.111
, pp. 127-138
-
-
Chraibi, A.1
Vallet, V.2
Firsov, D.3
Hess, S.K.4
Horisberger, J.D.5
-
9
-
-
26944497948
-
The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion
-
Collino M, Patel NS, Lawrence KM, Collin M, Latchman DS, Yaqoob MM, Thiemermann C (2005) The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. Kidney Int 68:529-536
-
(2005)
Kidney Int
, vol.68
, pp. 529-536
-
-
Collino, M.1
Patel, N.S.2
Lawrence, K.M.3
Collin, M.4
Latchman, D.S.5
Yaqoob, M.M.6
Thiemermann, C.7
-
10
-
-
18244392958
-
+ channel cell surface expression
-
+ channel cell surface expression. EMBO J 20:7052-7059
-
(2001)
EMBO J
, vol.20
, pp. 7052-7059
-
-
Debonneville, C.1
Flores, S.Y.2
Kamynina, E.3
Plant, P.J.4
Tauxe, C.5
Thomas, M.A.6
Munster, C.7
Chraibi, A.8
Pratt, J.H.9
Horisberger, J.D.10
Pearce, D.11
Loffing, J.12
Staub, O.13
-
11
-
-
4644240440
-
A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoidinducible kinase consensus motif in the C terminus of the channel's alpha-subunit
-
Diakov A, Korbmacher C (2004) A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoidinducible kinase consensus motif in the C terminus of the channel's alpha-subunit. J Biol Chem 279:38134-38142
-
(2004)
J Biol Chem
, vol.279
, pp. 38134-38142
-
-
Diakov, A.1
Korbmacher, C.2
-
12
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARgamma gene
-
Fajas L, Auboeuf D, Raspe E, Schoonjans K, Lefebvre AM, Saladin R, Najib J, Laville M, Fruchart JC, Deeb S, Vidal-Puig A, Flier J, Briggs MR, Staels B, Vidal H, Auwerx J (1997) The organization, promoter analysis, and expression of the human PPARgamma gene. J Biol Chem 272:18779-18789
-
(1997)
J Biol Chem
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
13
-
-
0032582349
-
PPARgamma3 mRNA: A distinct PPARgamma mRNA subtype transcribed from an independent promoter
-
Fajas L, Fruchart JC, Auwerx J (1998) PPARgamma3 mRNA: A distinct PPARgamma mRNA subtype transcribed from an independent promoter. FEBS Lett 438:55-60
-
(1998)
FEBS Lett
, vol.438
, pp. 55-60
-
-
Fajas, L.1
Fruchart, J.C.2
Auwerx, J.3
-
14
-
-
32644460092
-
From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
-
Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W (2006) From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45:120-159
-
(2006)
Prog Lipid Res
, vol.45
, pp. 120-159
-
-
Feige, J.N.1
Gelman, L.2
Michalik, L.3
Desvergne, B.4
Wahli, W.5
-
16
-
-
0028972025
-
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83:803-812
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
17
-
-
15344340558
-
A novel epithelial sodium channel beta-subunit mutation associated with hypertensive Liddle syndrome
-
Freundlich M, Ludwig M (2005) A novel epithelial sodium channel beta-subunit mutation associated with hypertensive Liddle syndrome. Pediatr Nephrol 20:512-515
-
(2005)
Pediatr Nephrol
, vol.20
, pp. 512-515
-
-
Freundlich, M.1
Ludwig, M.2
-
19
-
-
0034024914
-
Clinical efficacy of new thiazolidinediones and glinides in the treatment of type 2 diabetes mellitus
-
Fuchtenbusch M, Standl E, Schatz H (2000) Clinical efficacy of new thiazolidinediones and glinides in the treatment of type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes 108:151-163
-
(2000)
Exp Clin Endocrinol Diabetes
, vol.108
, pp. 151-163
-
-
Fuchtenbusch, M.1
Standl, E.2
Schatz, H.3
-
20
-
-
0031408955
-
Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans
-
Guan Y, Zhang Y, Davis L, Breyer MD (1997) Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. Am J Physiol Renal Physiol 273:F1013-F1022
-
(1997)
Am J Physiol Renal Physiol 273
-
-
Guan, Y.1
Zhang, Y.2
Davis, L.3
Breyer, M.D.4
-
21
-
-
23844472901
-
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption
-
Guan Y, Hao C, Cha DR, Rao R, Lu W, Kohan DE, Magnuson MA, Redha R, Zhang Y, Breyer MD (2005) Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat Med 11:861-866
-
(2005)
Nat Med
, vol.11
, pp. 861-866
-
-
Guan, Y.1
Hao, C.2
Cha, D.R.3
Rao, R.4
Lu, W.5
Kohan, D.E.6
Magnuson, M.A.7
Redha, R.8
Zhang, Y.9
Breyer, M.D.10
-
22
-
-
0029092801
-
Hypertension caused by a truncated epithelial sodium channel gamma subunit: Genetic heterogeneity of Liddle syndrome
-
Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets R, Lu Y, Canessa C, Iwasaki T, Rossier B, Lifton RP (1995) Hypertension caused by a truncated epithelial sodium channel gamma subunit: Genetic heterogeneity of Liddle syndrome. Nat Genet 11:76-82
-
(1995)
Nat Genet
, vol.11
, pp. 76-82
-
-
Hansson, J.H.1
Nelson-Williams, C.2
Suzuki, H.3
Schild, L.4
Shimkets, R.5
Lu, Y.6
Canessa, C.7
Iwasaki, T.8
Rossier, B.9
Lifton, R.P.10
-
23
-
-
0033598091
-
Pulmonary edema associated with troglitazone therapy
-
Hirsch IB, Kelly J, Cooper S (1999) Pulmonary edema associated with troglitazone therapy. Arch Intern Med 159:1811
-
(1999)
Arch Intern Med
, vol.159
, pp. 1811
-
-
Hirsch, I.B.1
Kelly, J.2
Cooper, S.3
-
24
-
-
85076402204
-
PPARgamma activation enhances cell surface ENaCalpha via up-regulation of SGK1 in human collecting duct cells
-
Hong G, Lockhart A, Davis B, Rahmoune H, Baker S, Ye L, Thompson P, Shou Y, O'Shaughnessy K, Ronco P, Brown J (2003) PPARgamma activation enhances cell surface ENaCalpha via up-regulation of SGK1 in human collecting duct cells. FASEB J 17:1966-1968
-
(2003)
FASEB J
, vol.17
, pp. 1966-1968
-
-
Hong, G.1
Lockhart, A.2
Davis, B.3
Rahmoune, H.4
Baker, S.5
Ye, L.6
Thompson, P.7
Shou, Y.8
O'Shaughnessy, K.9
Ronco, P.10
Brown, J.11
-
26
-
-
33749500123
-
Pathophysiological significance of the serumand glucocorticoid-inducible kinase isoforms
-
Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V (2006) (Patho)physiological significance of the serumand glucocorticoid-inducible kinase isoforms. Physiol Rev 86:1151-1178
-
(2006)
Physiol Rev
, vol.86
, pp. 1151-1178
-
-
Lang, F.1
Bohmer, C.2
Palmada, M.3
Seebohm, G.4
Strutz-Seebohm, N.5
Vallon, V.6
-
27
-
-
69549105897
-
The physiological impact of the serum and glucocorticoid-inducible kinase SGK1
-
Lang F, Artunc F, Vallon V (2009) The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens 18:439-448
-
(2009)
Curr Opin Nephrol Hypertens
, vol.18
, pp. 439-448
-
-
Lang, F.1
Artunc, F.2
Vallon, V.3
-
29
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
30
-
-
0030068024
-
Molecular genetics of human blood pressure variation
-
Lifton RP (1996) Molecular genetics of human blood pressure variation. Science 272:676-680
-
(1996)
Science
, vol.272
, pp. 676-680
-
-
Lifton, R.P.1
-
31
-
-
64149085069
-
Regulated sodium transport in the renal connecting tubule (CNT)via the epithelial sodium channel (ENaC)
-
Loffing J, Korbmacher C (2009) Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). Pflugers Arch 458:111-135
-
(2009)
Pflugers Arch
, vol.458
, pp. 111-135
-
-
Loffing, J.1
Korbmacher, C.2
-
34
-
-
74049146190
-
Role of the C-terminal part of the extracellular domain of the alpha-ENaC in activation by sulfonylurea glibenclamide
-
Renauld S, Chraibi A (2009) Role of the C-terminal part of the extracellular domain of the alpha-ENaC in activation by sulfonylurea glibenclamide. J Membr Biol 230:133-141
-
(2009)
J Membr Biol
, vol.230
, pp. 133-141
-
-
Renauld, S.1
Chraibi, A.2
-
35
-
-
51149110757
-
Ile481 from the guinea-pig alpha-subunit plays a major role in the activation of ENaC by cpt-cAMP
-
Renauld S, Allache R, Chraibi A (2008) Ile481 from the guinea-pig alpha-subunit plays a major role in the activation of ENaC by cpt-cAMP. Cell Physiol Biochem 22:101-108
-
(2008)
Cell Physiol Biochem
, vol.22
, pp. 101-108
-
-
Renauld, S.1
Allache, R.2
Chraibi, A.3
-
36
-
-
33746381173
-
Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat
-
Riazi S, Khan O, Tiwari S, Hu X, Ecelbarger CA (2006) Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat. Am J Nephrol 26:245-257
-
(2006)
Am J Nephrol
, vol.26
, pp. 245-257
-
-
Riazi, S.1
Khan, O.2
Tiwari, S.3
Hu, X.4
Ecelbarger, C.A.5
-
38
-
-
65349084594
-
The role of Sgk-1 in the upregulation of transport proteins by PPARgamma agonists in human proximal tubule cells
-
Saad S, Agapiou DJ, Chen XM, Stevens V, Pollock CA (2009) The role of Sgk-1 in the upregulation of transport proteins by PPARgamma agonists in human proximal tubule cells. Nephrol Dial Transplant 24:1130-1141
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1130-1141
-
-
Saad, S.1
Agapiou, D.J.2
Chen, X.M.3
Stevens, V.4
Pollock, C.A.5
-
39
-
-
0027946089
-
Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
-
Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR Jr, Ulick S, Milora RV, Findling JW et al (1994) Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell 79:407-414
-
(1994)
Cell
, vol.79
, pp. 407-414
-
-
Shimkets, R.A.1
Warnock, D.G.2
Bositis, C.M.3
Nelson-Williams, C.4
Hansson, J.H.5
Schambelan, M.6
Gill Jr., J.R.7
Ulick, S.8
Milora, R.V.9
Findling, J.W.10
-
40
-
-
0029591506
-
+ channel
-
+ channel. Cell 83:969-978
-
(1995)
Cell
, vol.83
, pp. 969-978
-
-
Snyder, P.M.1
Price, M.P.2
McDonald, F.J.3
Adams, C.M.4
Volk, K.A.5
Zeiher, B.G.6
Stokes, J.B.7
Welsh, M.J.8
-
42
-
-
1642457244
-
Rosiglitazone activates renal sodium- and water-reabsorptive pathways and lowers blood pressure in normal rats
-
Song J, Knepper MA, Hu X, Verbalis JG, Ecelbarger CA (2004) Rosiglitazone activates renal sodium- and water-reabsorptive pathways and lowers blood pressure in normal rats. J Pharmacol Exp Ther 308:426-433
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 426-433
-
-
Song, J.1
Knepper, M.A.2
Hu, X.3
Verbalis, J.G.4
Ecelbarger, C.A.5
-
43
-
-
38449083331
-
Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar
-
Spraggs C, McCarthy A, McCarthy L, Hong G, Hughes A, Lin X, Sathe G, Smart D, Traini C, Van Horn S, Warren L, Mosteller M (2007) Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar. Pharmacogenet Genomics 17:1065-1076
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 1065-1076
-
-
Spraggs, C.1
McCarthy, A.2
McCarthy, L.3
Hong, G.4
Hughes, A.5
Lin, X.6
Sathe, G.7
Smart, D.8
Traini, C.9
Van Horn, S.10
Warren, L.11
Mosteller, M.12
-
47
-
-
38349016575
-
Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells
-
Taruno A, Niisato N, Marunaka Y (2008) Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells. Am J Physiol Renal Physiol 294:F177-F186
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Taruno, A.1
Niisato, N.2
Marunaka, Y.3
-
48
-
-
4344592072
-
New insights into epithelial sodium channel function in the kidney: Site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis
-
Thomas CP, Itani OA (2004) New insights into epithelial sodium channel function in the kidney: Site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis. Curr Opin Nephrol Hypertens 13:541-548
-
(2004)
Curr Opin Nephrol Hypertens
, vol.13
, pp. 541-548
-
-
Thomas, C.P.1
Itani, O.A.2
-
49
-
-
0035103716
-
Pulmonary edema associated with rosiglitazone and troglitazone
-
Thomas ML, Lloyd SJ (2001) Pulmonary edema associated with rosiglitazone and troglitazone. Ann Pharmacother 35:123-124
-
(2001)
Ann Pharmacother
, vol.35
, pp. 123-124
-
-
Thomas, M.L.1
Lloyd, S.J.2
-
50
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARgamma
-
Tontonoz P, Spiegelman BM (2008) Fat and beyond: The diverse biology of PPARgamma. Annu Rev Biochem 77:289-312
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
51
-
-
12144279572
-
New insights into the role of serum- And glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure
-
Vallon V, Lang F (2005) New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure. Curr Opin Nephrol Hypertens 14:59-66
-
(2005)
Curr Opin Nephrol Hypertens
, vol.14
, pp. 59-66
-
-
Vallon, V.1
Lang, F.2
-
52
-
-
0034923501
-
Peroxisome proliferator- Activated receptor gamma and metabolic disease
-
Willson TM, Lambert MH, Kliewer SA (2001) Peroxisome proliferator- activated receptor gamma and metabolic disease. Annu Rev Biochem 70:341-367
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 341-367
-
-
Willson, T.M.1
Lambert, M.H.2
Kliewer, S.A.3
-
53
-
-
0036840696
-
+ retention in the sgk1- Knockout mouse
-
+ retention in the sgk1- knockout mouse. J Clin Invest 110:1263-1268
-
(2002)
J Clin Invest
, vol.110
, pp. 1263-1268
-
-
Wulff, P.1
Vallon, V.2
Huang, D.Y.3
Volkl, H.4
Yu, F.5
Richter, K.6
Jansen, M.7
Schlunz, M.8
Klingel, K.9
Loffing, J.10
Kauselmann, G.11
Bosl, M.R.12
Lang, F.13
Kuhl, D.14
-
54
-
-
53149149804
-
Renal and vascular mechanisms of thiazolidinedione-induced fluid retention
-
Yang T, Soodvilai S (2008) Renal and vascular mechanisms of thiazolidinedione-induced fluid retention. PPAR Res 2008: 943614
-
(2008)
PPAR Res
, vol.2008
, pp. 943614
-
-
Yang, T.1
Soodvilai, S.2
-
55
-
-
62749160909
-
Nephrotic syndrome: New concepts in the pathophysiology of sodium retention
-
Zacchia M, Trepiccione F, Morelli F, Pani A, Capasso G (2008) Nephrotic syndrome: New concepts in the pathophysiology of sodium retention. J Nephrol 21:836-842
-
(2008)
J Nephrol
, vol.21
, pp. 836-842
-
-
Zacchia, M.1
Trepiccione, F.2
Morelli, F.3
Pani, A.4
Capasso, G.5
-
56
-
-
21544479710
-
Collecting duct-specific deletion of peroxisome proliferator- activated receptor gamma blocks thiazolidinedione-induced fluid retention
-
Zhang H, Zhang A, Kohan DE, Nelson RD, Gonzalez FJ, Yang T (2005) Collecting duct-specific deletion of peroxisome proliferator- activated receptor gamma blocks thiazolidinedione-induced fluid retention. Proc Natl Acad Sci USA 102:9406-9411
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9406-9411
-
-
Zhang, H.1
Zhang, A.2
Kohan, D.E.3
Nelson, R.D.4
Gonzalez, F.J.5
Yang, T.6
|