Changed crystallinity of mebendazole solid dispersion: Improved anthelmintic activity

International Journal of Pharmaceutics

Volumn 403, Issue 1-2, 2011, Pages 23-28

  García Rodriguez, Juan J ^a   De La Torre Iglesias, Paloma M ^a   Vegas Sánchez, M Carmen ^a   Torrado Durán, Susana ^a   Bolás Fernández, Francisco ^a   Torrado Santiago, Santiago ^b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Anthelmintic activity; Dissolution rate; Mebendazole; Powder X ray diffraction; Solid dispersions

Indexed keywords

HYDROXYPROPYLCELLULOSE; MEBENDAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHELMINTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STRUCTURE; FREEZE DRYING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRICHINOSIS; X RAY DIFFRACTION;

ANIMALS; ANTINEMATODAL AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG CARRIERS; MEBENDAZOLE; MICE; MICROSCOPY, ELECTRON, SCANNING; SOLUBILITY; SURFACE PROPERTIES; TRICHINELLA SPIRALIS; TRICHINELLOSIS; X-RAY DIFFRACTION;

EID: 78650179831     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.002     Document Type: Article

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