QSAR Analysis for Some Diaryl-substituted Pyrazoles as CCR2 Inhibitors by GA-Stepwise MLR

Chemical Biology and Drug Design

Volumn 77, Issue 1, 2011, Pages 75-85

  Saghaie, Lotfollah ^a   Shahlaei, Mohsen ^a,b   Fassihi, Afshin ^a,c   Madadkar Sobhani, Armin ^d   Gholivand, Mohammad B ^e   Pourhossein, Alireza ^f  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c Isfahan Pharmaceutical Sciences Research Center   (Iran)

^d UNIVERSITY OF TEHRAN   (Iran)

^e RAZI UNIVERSITY   (Iran)

^f ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

CCR2 inhibitors; Genetic algorithm; Multivariate linear regression; Quantitative structure property relationship

Indexed keywords

CHEMOKINE RECEPTOR CCR2; PYRAZOLE;

ARTICLE; GENETIC ALGORITHM; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RANDOMIZATION; RELIABILITY;

ALGORITHMS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; MULTIVARIATE ANALYSIS; NEURAL NETWORKS (COMPUTER); PYRAZOLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, CCR2; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS;

EID: 78650120896     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.01053.x     Document Type: Article

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