Fingerprint directed scaffold hopping for identification of CCR2 antagonists

Journal of Chemical Information and Modeling

Volumn 48, Issue 9, 2008, Pages 1891-1902

  Nair, Pramod C ^a   Sobhia, M Elizabeth ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN BONDS; LIGANDS; MOLECULES;

CHEMOKINE RECEPTORS; HYDROGEN BONDING INTERACTIONS; HYDROPHOBIC BINDING; IMMUNO MODULATIONS; MULTIPLE SCLEROSIS; N-TERMINAL DOMAINS; RECEPTOR FLEXIBILITY; SIMILARITY METRICS;

PALMPRINT RECOGNITION;

CCRL1 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR; CHEMOKINE RECEPTOR CCR2; LIGAND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG DESIGN; HUMAN; HYDROPHOBICITY; IC 50; METABOLISM; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

COMPUTER SIMULATION; DRUG DESIGN; HUMANS; HYDROPHOBICITY; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, CCR; RECEPTORS, CCR2;

EID: 54249157966     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci800157j     Document Type: Article

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