DNA binding characteristics of mithramycin and chromomycin analogues obtained by combinatorial biosynthesis

Biochemistry

Volumn 49, Issue 49, 2010, Pages 10543-10552

  Barceló, Francisca ^a   Ortiz Lombardía, Miguel ^b   Martorell, Miquel ^a   Oliver, Miquel ^a   Méndez, Carmen ^c   Salas, José A ^c   Portugal, José ^d  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^b AIX MARSEILLE UNIVERSITY   (France)

^c UNIVERSITY OF OVIEDO   (Spain)

^d INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER AGENTS; ANTIPROLIFERATIVE ACTIVITIES; ANTITUMOR ANTIBIOTICS; BINDING AFFINITIES; BINDING PARAMETER; BIOLOGICAL ACTIVITIES; CHROMOMYCIN A; COMBINATORIAL BIOSYNTHESIS; DICATIONS; DNA BINDING; DNA BINDING AFFINITY; GENE PROMOTER; MINOR GROOVES; MITHRAMYCIN; SIDE CHAINS; SIDE EFFECT; SPECTROSCOPIC CHARACTERIZATION;

ANTIBIOTICS; BINDING ENERGY; BIOACTIVITY; BIOCHEMISTRY; BIOSYNTHESIS; CHROMOPHORES; THERMODYNAMICS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

DNA;

CHROMOMYCIN; CHROMOMYCIN A3; MAGNESIUM ION; MITHRAMYCIN;

ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CHROMATOPHORE; DNA BINDING; NONHUMAN; PRIORITY JOURNAL; SALMON; STOICHIOMETRY; TESTIS; THERMODYNAMICS;

ANIMALS; BINDING SITES; CHROMOMYCINS; COMBINATORIAL CHEMISTRY TECHNIQUES; DNA; MALE; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PLICAMYCIN; SALMON; TESTIS; THERMODYNAMICS;

EID: 78650108126     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101398s     Document Type: Article

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