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Volumn 33, Issue 4, 2005, Pages 1352-1361
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Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity
a,b,c
a,b
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Author keywords
[No Author keywords available]
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Indexed keywords
COBALT;
DOUBLE STRANDED DNA;
FERRIC ION;
HYDROGEN PEROXIDE;
MAGNESIUM ION;
MANGANESE;
METAL COMPLEX;
MITHRAMYCIN;
NICKEL;
PLASMID DNA;
ZINC ION;
ANTINEOPLASTIC ANTIBIOTIC;
BIS(MITHROMYCIN)IRON(II);
DIVALENT CATION;
DNA;
DRUG DERIVATIVE;
FERROUS ION;
IRON CHELATING AGENT;
METAL;
ARTICLE;
BINDING AFFINITY;
BINDING KINETICS;
CANCER CELL CULTURE;
CELL STRAIN K 562;
CIRCULAR DICHROISM;
COMPLEX FORMATION;
CONTROLLED STUDY;
DNA CLEAVAGE;
DNA STRAND BREAKAGE;
DRUG CYTOTOXICITY;
DRUG DNA INTERACTION;
DRUG STRUCTURE;
FLUORESCENCE MICROSCOPY;
HUMAN;
HUMAN CELL;
IRON CHELATION;
MEMBRANE TRANSPORT;
PRIORITY JOURNAL;
SURFACE PLASMON RESONANCE;
CELL MEMBRANE PERMEABILITY;
CHEMICAL STRUCTURE;
CHEMISTRY;
CONFORMATION;
METABOLISM;
NUCLEOTIDE SEQUENCE;
PLASMID;
TUMOR CELL LINE;
ANTIBIOTICS, ANTINEOPLASTIC;
BASE SEQUENCE;
CATIONS, DIVALENT;
CELL LINE, TUMOR;
CELL MEMBRANE PERMEABILITY;
CIRCULAR DICHROISM;
DNA;
FERROUS COMPOUNDS;
HUMANS;
IRON CHELATING AGENTS;
K562 CELLS;
METALS;
MODELS, MOLECULAR;
NUCLEIC ACID CONFORMATION;
PLASMIDS;
PLICAMYCIN;
SURFACE PLASMON RESONANCE;
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EID: 14844361385
PISSN: 03051048
EISSN: 13624962
Source Type: Journal
DOI: 10.1093/nar/gki276 Document Type: Article |
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Times cited : (28)
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References (0)
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