DNA double-strand break repair defects in syndromes associated with acute radiation response: At least two different assays to predict intrinsic radiosensitivity?

International Journal of Radiation Biology

Volumn 84, Issue 2, 2008, Pages 107-125

  Joubert, Aurélie ^a,b   Zimmerman, Kristin M ^a   Bencokova, Zuzana ^a   Gastaldo, Jérôme ^a   Chavaudra, Nicole ^c   Favaudon, Vincent ^a   Arlett, Colin F ^d   Foray, Nicolas ^a  

^a INSERM   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

DNA PK; DSB repair; MRE11; pH2AX; Radiosensitivity

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; HISTONE H2AX; MRE11 PROTEIN; PROTEIN ANTIBODY;

ARTICLE; ASSAY; CHROMOSOME ABERRATION; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; FIBROBLAST; GENE MUTATION; GENETIC DISORDER; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOFLUORESCENCE; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULSED FIELD GEL ELECTROPHORESIS; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION INJURY; RADIATION RESPONSE; RADIOSENSITIVITY;

BIOLOGICAL ASSAY; CELL LINE; CELL SURVIVAL; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; ELECTROPHORESIS, GEL, PULSED-FIELD; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; FORECASTING; HUMANS; RADIATION TOLERANCE; TIME FACTORS; X-RAYS;

EID: 38849135851     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.1080/09553000701797039     Document Type: Article

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