Toll-like receptor 4 signalling pathway activation in a rat model of Acanthamoeba Keratitis

Parasite Immunology

Volumn 33, Issue 1, 2011, Pages 25-33

  Ren, M Y ^a   Wu, X Y ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Acanthamoeba keratitis; Cornea; Innate immunity; Toll like receptors

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BETA INTERFERON; I KAPPA B KINASE BETA; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MYELOID DIFFERENTIATION FACTOR 88; PYRROLIDINE DITHIOCARBAMATE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ACANTHAMOEBA; ACANTHAMOEBA KERATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA; HUMAN; IMMUNOCYTOCHEMISTRY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACANTHAMOEBA; ACANTHAMOEBA KERATITIS; ANIMALS; BLOTTING, WESTERN; CORNEA; DISEASE MODELS, ANIMAL; EPITHELIUM, CORNEAL; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON-BETA; INTERLEUKIN-8; NF-KAPPA B; POLYMERASE CHAIN REACTION; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

ACANTHAMOEBA; ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 78650047036     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2010.01247.x     Document Type: Article

References (35)

1. Jones DB, Visvesvara GS & Robinson NM. Acanthamoeba polyphaga keratitis and Acanthamoeba uveitis associated with fatal meningoencephalitis. Trans Ophthalmol Soc UK 1975; 95: 221-232.
2. Radford CF, Minassian DC & Dart JK. AK in England and Wales: incidence, outcome, and risk factors. Br J Ophthalmol 2002; 86: 536-542.
3. Seal DV, Beattie TK, Tomlinson A, Fan D & Wong E. Acanthamoeba Keratitis. Br J Ophthalmol 2003; 87: 516-517.
4. Bharathi MJ, Srinivasan M, Ramakrishnan R, Meenakshi R, Padmacathy S & Lalitha PN. A study of the spectrum of AK: a three-year study at a tertuary eye care referral center in South India. Indian J Ophthalmol 2007; 55: 37-42.
5. Gooi P, Lee-Wing M, Brownstein S, El-Defrawy S, Jackson WB & Mintsioulis G. Acanthamoeba keratitis: persistent organisms without inflammation after 1 year of topical chlorhexidine. Cornea 2008; 27(2): 246-248.
6. Yang Z, Cao Z & Panjwani N. Pathogenesis of Acanthamoeba keratitis: carbohydrate-mediated host-parasite interactions. Infect Immun 1997; 65(2): 439-445.
7. Vemuganti GK, Sharma S, Athmanathan S & Garg P. Keratocyte loss in Acanthamoeba keratitis: phagocytosis, necrosis or apoptosis? Indian J Ophthalmol 2000; 48(4): 291-294.
8. Na BK, Kim JC & Song CY. Characterization and pathogenetic role of proteinase from Acanthamoeba castellanii. Microb Pathog 2001; 30(1): 39-48.
9. Garate M, Marchant J, Cubillos I, Cao Z, Kban AN & Panjwani N. In vitro pathogenicity of Acanthamoeba is associated with the expression of the mannose-binding protein. Invest Ophthalmol Vis Sci 2006; 47: 1056-1062.
10. Janeway CA Jr & Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002; 20: 197-216.
11. Akira S & Takeda K. Toll-like receptor signaling. Nat Rev Immunol 2004; 4: 499-511.
12. Akira S & Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003; 85: 85-95.
13. Campos MA & Gazzinelli RT. Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors. Mediators Inflamm 2004; 13(3): 139-143.
14. Aderem A & Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000; 406: 782-787.
15. Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP & Tripp RA. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000; 1: 398-401.
16. Triantafilou K & Triantafilou M. Coxsachievirus B4 induced cytokine production in pancreatic cells is mediated through Toll-like receptor 4. J Virol 2004; 78: 11313-11320.
17. Compton T, Kurt-Jones EA, Boehme KW, et al. Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol 2003; 77: 4588-4596.
18. Biekack K, Lien E, Klagge IM, et al. Hemagglutinin protein of wild-type measles virus activate toll-like receptor 2 signaling. J Virol 2002; 76: 8729-8736.
19. Kurt-Jones EA, Chan M, Zhou S, et al. Herps simplex virus 1 interaction with Toll-like receptor2 contribute to lethal encephalitis. Proc Natl Acad Sci USA 2004; 101: 1315-1320.
20. Cohen-Sfady M, Nussbaum G, Pevsner-Fischer M, et al. Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. J Immunol 2005; 175(6): 3594-3602.
21. Zhang J, Xu K, Ambati B, et al. Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin. Invest Ophthamol Vis Sci 2003; 44: 4247-4254.
22. Ren MY, Gao L & Wu XY. TLR4: the receptor bridging Acanthamoeba challenge and intracellular inflammatory responses in human corneal cell lines. Immunol Cell Biol 2010; 88: 529-536.
23. Yu FS & Hazlett LD. Toll-like receptors and the eye. Invest Ophthalmol Vis Sci 2006; 47(4): 1255-1263.
24. Takeuchi O, Hoshino K, Kawai T, et al. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive cell wall components. Immunity 1999; 11: 443-451.
25. Schwandner R, Dziarski R, Wesche H, Rothe M & Kirschning CJ. Peptidoglycan and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J Biol Chem 1999; 274: 17406-17409.
26. Underhill DM, Ozinsky A, Hajjar AM, et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999; 401: 811-815.
27. Coelho PS, Klein A, Talvani A, et al. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes induce in vivo leukocyte recruitment dependent on MCP-1 production by IFN-γ-primed- macrophages. J Leukoc Biol 2002; 71: 837-844.
28. Asea A, Rehli M, Kabingu E, et al. Novel signal transduction pathway utilized by extracellular HSP70: role of Toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002; 277: 15028-15034.
29. Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-2088.
30. Okamura Y, Watari M, Jerud ES, et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001; 276: 10229-10233.
31. Johnson GB, Brunn GJ, Kodaira Y & Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002; 168: 5233-5239.
32. Chang JH, McCluskey PJ & Wakefield D. Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease. Br J Ophthalmol 2006; 90(1): 103-108.
33. Marsik C, Mayr F, Cardona F, Derhaschnig U, Wagner OF & Jilma B. Endotoxaemia modulates Toll-like receptors on leucocytes in humans. Br J Haematol 2003; 121(4): 653-656.
34. Vlahopoulos S, Boldogh I, Casola A & Brasier AR. Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation. Blood 1999; 94(6): 1878-1889.
35. Yamamoto M, Sato S, Mori K, et al. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 2002; 169: 6668-6672.