CSF transthyretin neuroprotection in a mouse model of brain ischemia

Journal of Neurochemistry

Volumn 115, Issue 6, 2010, Pages 1434-1444

  Santos, Sofia Duque ^a   Lambertsen, Kate Lykke ^b   Clausen, Bettina Hjelm ^b   Akinc, Akin ^c   Alvarez, Rene ^d   Finsen, Bente ^b   Saraiva, Maria João ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c UNIVERSITY OF PORTO   (Portugal)

^d ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

brain ischemia; heat shock transcription factor 1; permanent middle cerebral artery occlusion; RNAi; transthyretin

Indexed keywords

BETA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CD11B ANTIGEN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MELATONIN 2 RECEPTOR; MESSENGER RNA; PREALBUMIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL DEATH; CELL LOSS; CONTROLLED STUDY; ENCEPHALITIS; HETEROZYGOSITY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; STROKE;

ANIMALS; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; CELL DEATH; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; PREALBUMIN;

MUS;

EID: 78650023374     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07047.x     Document Type: Article

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