Response of the brain to oligemia: Gene expression, c-Fos, and Nrf2 localization

Molecular Brain Research

Volumn 126, Issue 1, 2004, Pages 57-66

  Liverman, Christopher S ^a   Cui, Lisa ^a   Yong, Chi ^a   Choudhuri, Rajani ^a   Klein, Robert M ^a   Welch, K Michael A ^b   Berman, Nancy E J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

Brain metabolism and blood flow; c Fos; Heat shock protein; Nrf 2; Oligemia; Other systems of the CNS; Oxidative stress; Transthyretin

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; NUCLEAR FACTOR; NUCLEAR FACTOR E2 RELATED FACTOR 2; PROTEIN C FOS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN NERVE CELL; BRAIN PERFUSION; CELL NUCLEUS; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; DETOXIFICATION; GENE EXPRESSION; HOMEOSTASIS; HYPHEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; LASER DOPPLER FLOWMETRY; LIQUID; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURKINJE CELL; REPERFUSION; SURGICAL TECHNIQUE; TIME; UPREGULATION;

ANIMALS; BRAIN; CEREBROVASCULAR CIRCULATION; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LASER-DOPPLER FLOWMETRY; MALE; MICE; MICE, INBRED C57BL; NEURONS; NF-E2-RELATED FACTOR 2; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-FOS; REGIONAL BLOOD FLOW; TRANS-ACTIVATORS;

EID: 2942630803     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2004.02.028     Document Type: Article

References (46)

1. Alam J., Stewart D., Touchard C., Boinapally S., Choi A.M.K., Cook J.L. Nrf2, the cap 'n' collar transcription factor, regulates induction of the heme oxygenase-1 gene. J. Biol. Chem. 274:1999;26071-26078
2. Aono J., Yanagawa T., Itoh K., Li B., Yoshida H., Kumagai Y., Yamamoto M., Ishii T. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem. Biophys. Res. Commun. 305:2003;271-277
3. Baron J.C. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications. Cerebrovasc. Dis. 11(Suppl. 1):2001;2-8
4. Blurton-Jones M.M., Roberts J.A., Tuszynski M.H. Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase. J. Comp. Neurol. 405:1999;529-542
5. Bodineau L., Larnicol N. Brainstem and hypothalamic areas activated by tissue hypoxia: Fos-like immunoreactivity induced by carbon monoxide inhalation in the rat. Neuroscience. 108:2001;643-653
6. Chan K., Han X.D., Kan Y.W. An important function of Nrf2 in combating oxidative stress: detoxification of acetominophen. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4611-4616
7. Cho H.Y., Jedlicka A.E., Reddy S.P., Kensler T.W., Yamamoto M., Zhang L.Y., Kleeberger S.R. Role of NRF2 in protection against hyperoxic lung injury in mice. Am. J. Respir. Cell Mol. Biol. 26:2002;175-182
8. Choudhuri R., Cui L., Yong C., Bowyer S., Klein R.M., Welch K.M., Berman N.E. Cortical spreading depression and gene regulation: relevance to migraine. Ann. Neurol. 51:2002;499-506
9. Dale E.C., Yang X., Moore S.K., Shymala G. Cloning and characterization of the promoter for murine 84-kDa heat shock protein. Gene. 172:1996;279-284
10. De Araujo I.E., Kringelbach M.L., Rolls E.T., McGlone F. Human cortical responses to water in the mouth, and the effects of thirst. J. Neurophysiol. 90:2003;1865-1876
11. Emmert M.H., Hermann J.P. Differential forebrain c-fos mRNA induction by ether inhalation and novelty: evidence for distinctive stress pathways. Brain Res. 845:1999;60-67
12. Fisk G.D., Wyss J.M. Pressor and depressor sites are intermingled in the cingulate cortex of the rat. Brain Res. 754:1997;204-212
13. Hagan P.M., Poole S., Bristow A.F. Immunosuppressive activity of corticotrophin-releasing factor. Inhibition of interleukin-1 and interleukin-6 production by human mononuclear cells. Biochem. J. 281:1992;251-254
14. Hagan P.M., Poole S., Bristow A.F. Corticotrophin-releasing factor as a mediator of the acute-phase response in rats, mice and rabbits. J. Endocrinol. 136:1993;207-216
15. Hata R., Maeda K., Hermann D., Mies G., Hossman K.A. Evolution of brain infarction after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 20:2000;937-946
16. Heim C.M., Melzacka M., Kolasiewicz W., Jaros T., Sieklucka M., Wesermann W., Sontag K.H. Cerebral oligemic hypoxia and iron toxicity in the mesolimbic system of rats. J. Neural Transm., Suppl. 46:1995;161-169
17. Heim C., Zhang J., Lan J., Sieklucka M., Kurz T., Riederer P., Gerlach M., Sontag K.H. Cerebral oligemia episode triggers free radical formation and late cognitive deficiencies. Eur. J. Neurosci. 12:2000;715-725
18. Huang H.-C., Nguyen T., Pickett C.B. Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2. Proc. Natl. Acad. Sci. U. S. A. 97:2000;12475-12480
19. Ishii T., Itoh K., Sato H., Bannai S. Oxidative stress-inducible proteins in macrophages. Free Radic. Res. 31:1999;351-355
20. Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236:1997;313-322
21. Kalaria R.N., Cohen D.L., Premkumar D.R., Nag S., LaManna J.C., Lust W. Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia. Mol. Brain Res. 62:1998;101-105
22. Kalwy S.A., Akbar M.T., Coffin R.S., de Belleroche J., Latchman D.S. Heat shock protein 27 delivered via herpes simplex virus vector can protect neuons of the hippocampus against kainic-acid-induced cell loss. Mol. Brain Res. 111:2003;91-103
23. Kelly K.J., Baird N.R., Greene A.L. Induction of stress response proteins and experimental renal ischemia/reperfusion. Kidney Int. 59:2001;1798-1802
24. Krukoff T.L., MacTavish D., Harris K.H., Jhamandas J.H. Changes in blood volume and pressure induce c-Fos expression in brainstem neurons that project to the paraventricular nucleus of the hypothalamus. Mol. Brain Res. 34:1995;99-108
25. Laer S., Block F., Huether G., Heim C., Sontag K.H. Effect of transient reduction of cerebral blood flow in normotensive rats on striatal dopamine-release. J. Neural Transm.: Gen. Sect. 92:1993;203-211
26. Lauritzen M. Pathophysiology of the migraine aura. The spreading depression theory. Brain. 117:1994;199-210
27. McMahon M., Itoh K., Yamamota M., Chanas S.A., Henderson C.J., McLellan L.I., Wolf C.R., Cavin C.C., Hayes J.D. The cap 'n' collar basic leucine zipper transcription factor Nrf (NF-E2 p45-related Factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res. 61:2001;3299-3307
28. Moi P., Chan K., Asunis I., Cao A., Kan Y.W. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc. Natl. Acad. Sci. U. S. A. 91:1994;9926-9930
29. Nunn J.A., Jarrard L.E. Silver impregnation reveals neuronal damage in cingulate cortex following 4 VO ischaemia in the rat. NeuroReport. 5:1994;2363-2366
30. Olesen J. Cerebral and extracranial circulatory disturbances in migraine: pathophysiological implications. Cerebrovasc. Brain Metab. Rev. 3:1991;1-28
31. Sawchenko P.E., Brown E.R., Chan R.K., Ericsson A., Li H.Y., Roland B.L., Kovacs K.J. The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress. Prog. Brain Res. 107:1996;201-222
32. Seiber F.E., Palmon S.C., Traystman R.J., Martin L.J. Global incomplete cerebral ischemia produces predominantly cortical neuronal injury. Stroke. 26:1995;2091-2095
33. Senisterra G.A., Lepock J.R. Thermal destabilization of transmembrane proteins by local anaesthetics. Int. J. Hypertherm. 16:2000;1-17
34. Sheng M., Greenberg M.E. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron. 4:1990;77-85
35. Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., Johnson J.A., Murphy T.H. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 23:2003;3394-3409
36. Smith M.L., Auer R.B., Siesjo B.K. The density and distribution of ischemic brain injury in the rat following 2-10 min. of forebrain ischemia. Acta Neuropathol. 64:1984;127-129
37. Stein T.D., Johnson J.A. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J. Neurosci. 22:2002;7380-7388
38. Thrivikraman K.V., Nemeroff C.B., Plotsky P.M. Sensitivity to glucocorticoid-mediated fast-feedback regulation of the hypothalamic-pituitary- adrenal axis is dependent upon stressor specific neurocircuitry. Brain Res. 870:2000;87-101
39. Toki T., Itoh J., Kitazawa J., Arai K., Hatakeyama K., Akasaka J., Igarashi K., Nomura N., Yokoyama M., Yamamoto M., Ito E. Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif. Oncogene. 14:1997;1901-1910
40. Tsuzuki K., Fukatsu, Yamaguchi H., Tateno M., Imai K., Fujii N., Yamauchi T. Transthyretin binds amyloid beta peptides, Abeta1-42 and Abeta1-40 to form complex in the autopsied human kidney-possible role of transthyretin for abeta sequestration. Neurosci. Lett. 281:2000;171-174
41. Valla J., Berndt J.D., Gonzalez-Lima F. Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration. J. Neurosci. 21:2001;4923-4930
42. Venogopal R., Jaiswal A.K. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H: quinone oxidoreductase1 gene. Proc. Natl. Acad. Sci. U. S. A. 93:1996;14960-14965
43. Wang S., Wang H., NiemiJunkola U., Westby G.W., McHaffie J.G., Stein B.E., Redgrave P. Parallel analyses of nociceptive neurones in rat superior colliculus by using c-Fos immunohistochemistry and electrophysiology under different conditions of anaesthesia. J. Comp. Neurol. 425:2000;599-615
44. Wasserman W.W., Fahl W.E. Functional antioxidant responsive elements. Proc. Natl. Acad. Sci. U. S. A. 94:1997;5361-5366
45. Welsh F.A., Moyer D.J., Harris V.A. Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain. J. Cereb. Blood Flow Metab. 12:1992;204-212
46. Welsh J.P., Yuen G., Placantonakis D.G., Vu T.Q., Haiss F., O'Hearn E., Molliver M.E., Aicher S.A. Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus. Adv. Neurol. 89:2002;331-359