Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: A role in cell adhesion and migration?

Brain Pathology

Volumn 21, Issue 1, 2011, Pages 44-54

  Van Strien, Miriam E ^a   Drukarch, Benjamin ^a   Bol, John G ^a   Van Der Valk, Paul ^a   Van Horssen, Jack ^a   Gerritsen, Wouter H ^a   Breve, John J ^a   Van Dam, Anne Marie ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

astrocytes; fibronectin; Multiple Sclerosis; tissue Transglutaminase

Indexed keywords

FIBRONECTIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADULT; AGED; ARTICLE; ASTROCYTE; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; EXTRACELLULAR MATRIX; FEMALE; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MULTIPLE SCLEROSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SCAR FORMATION; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ASTROCYTES; BLOTTING, WESTERN; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; EXTRACELLULAR MATRIX; FEMALE; FIBRONECTINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN SHEATH; RNA, SMALL INTERFERING; TRANSGLUTAMINASES;

EID: 78649985496     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2010.00428.x     Document Type: Article

References (58)

1. Akimov SS, Belkin AM, (2001) Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin. Blood 98: 1567-1576.
2. Akimov SS, Belkin AM, (2001) Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition. J Cell Sci 114: 2989-3000.
3. Akimov SS, Krylov D, Fleischman LF, Belkin AM, (2000) Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol 148: 825-838.
4. Amano M, Fukata Y, Kaibuchi K, (2000) Regulation and functions of Rho-associated kinase. Exp Cell Res 261: 44-51.
5. Antonyak MA, Singh US, Lee DA, Boehm JE, Combs C, Zgola MM, et al (2001) Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis. J Biol Chem 276: 33582-33587.
6. Barone MV, Caputo I, Ribecco MT, Maglio M, Marzari R, Sblattero D, et al (2007) Humoral immune response to tissue transglutaminase is related to epithelial cell proliferation in celiac disease. Gastroenterology 132: 1245-1253.
7. Benveniste EN, (1998) Cytokine actions in the central nervous system. Cytokine Growth Factor Rev 9: 259-275.
8. Bo L, Dawson TM, Wesselingh S, Mork S, Choi S, Kong PA, et al (1994) Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann Neurol 36: 778-786.
9. Bo L, Mork S, Kong PA, Nyland H, Pardo CA, Trapp BD, (1994) Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J Neuroimmunol 51: 135-146.
10. Bo L, Geurts JJ, Ravid R, Barkhof F, (2004) Magnetic resonance imaging as a tool to examine the neuropathology of multiple sclerosis. Neuropathol Appl Neurobiol 30: 106-117.
11. Campisi A, Caccamo D, Raciti G, Cannavo G, Macaione V, Curro M, et al (2003) Glutamate-induced increases in transglutaminase activity in primary cultures of astroglial cells. Brain Res 978: 24-30.
12. Choi K, Siegel M, Piper JL, Yuan L, Cho E, Strnad P, et al (2005) Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2. Chem Biol 12: 469-475.
13. De Groot CJ, Bergers E, Kamphorst W, Ravid R, Polman CH, Barkhof F, Van Der Valk P, (2001) Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p)reactive lesions. Brain 124: 1635-1645.
14. Forsprecher J, Wang Z, Nelea V, Kaartinen MT, (2009) Enhanced osteoblast adhesion on transglutaminase 2-crosslinked fibronectin. Amino Acids 36: 747-753.
15. Frohman EM, Racke MK, Raine CS, (2006) Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med 354: 942-955.
16. Gaudry CA, Verderio E, Aeschlimann D, Cox A, Smith C, Griffin M, (1999) Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain. J Biol Chem 274: 30707-30714.
17. Gaudry CA, Verderio E, Jones RA, Smith C, Griffin M, (1999) Tissue transglutaminase is an important player at the surface of human endothelial cells: evidence for its externalization and its colocalization with the beta(1) integrin. Exp Cell Res 252: 104-113.
18. Holley JE, Gveric D, Newcombe J, Cuzner ML, Gutowski NJ, (2003) Astrocyte characterization in the multiple sclerosis glial scar. Neuropathol Appl Neurobiol 29: 434-444.
19. Huang D, Han Y, Rani MR, Glabinski A, Trebst C, Sorensen T, et al (2000) Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation. Immunol Rev 177: 52-67.
20. Iismaa SE, Mearns BM, Lorand L, Graham RM, (2009) Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiol Rev 89: 991-1023.
21. John GR, Chen L, Rivieccio MA, Melendez-Vasquez CV, Hartley A, Brosnan CF, (2004) Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. J Neurosci 24: 2837-2845.
22. Junn E, Ronchetti RD, Quezado MM, Kim SY, Mouradian MM, (2003) Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci USA 100: 2047-2052.
23. Kim SY, Grant P, Lee JH, Pant HC, Steinert PM, (1999) Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease. J Biol Chem 274: 30715-30721.
24. Kornek B, Lassmann H, (2003) Neuropathology of multiple sclerosis-new concepts. Brain Res Bull 61: 321-326.
25. Lesort M, Chun W, Tucholski J, Johnson GV, (2002) Does tissue transglutaminase play a role in Huntington's disease? Neurochem Int 40: 37-52.
26. Mastroberardino PG, Farrace MG, Viti I, Pavone F, Fimia GM, Melino G, et al (2006) "Tissue" transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Biochim Biophys Acta 1757: 1357-1365.
27. Milner R, Crocker SJ, Hung S, Wang X, Frausto RF, Del Zoppo GJ, (2007) Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha5beta1 and alphavbeta5. J Immunol 178: 8158-8167.
28. Monsonego A, Shani Y, Friedmann I, Paas Y, Eizenberg O, Schwartz M, (1997) Expression of GTP-dependent and GTP-independent tissue-type transglutaminase in cytokine-treated rat brain astrocytes. J Biol Chem 272: 3724-3732.
29. Oliverio S, Amendola A, Rodolfo C, Spinedi A, Piacentini M, (1999) Inhibition of "tissue" transglutaminase increases cell survival by preventing apoptosis. J Biol Chem 274: 34123-34128.
30. Perry MJ, Haynes LW, (1993) Localization and activity of transglutaminase, a retinoid-inducible protein, in developing rat spinal cord. Int J Dev Neurosci 11: 325-337.
31. Ridet JL, Malhotra SK, Privat A, Gage FH, (1997) Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20: 570-577.
32. Ridley AJ, Hall A, (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70: 389-399.
33. Roberts ES, Zandonatti MA, Watry DD, Madden LJ, Henriksen SJ, Taffe MA, Fox HS, (2003) Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. Am J Pathol 162: 2041-2057.
34. Sakly W, Thomas V, Quash G, El AS, (2006) A role for tissue transglutaminase in alpha-gliadin peptide cytotoxicity. Clin Exp Immunol 146: 550-558.
35. Sarafian TA, Bredesen DE, (1994) Is apoptosis mediated by reactive oxygen species? Free Radic Res 21: 1-8.
36. Shi F, Harman J, Fujiwara K, Sottile J, (2010) Collagen I matrix turnover is regulated by fibronectin polymerization. Am J Physiol Cell Physiol 298: C1265-C1275.
37. Singh US, Pan J, Kao YL, Joshi S, Young KL, Baker KM, (2003) Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cells. J Biol Chem 278: 391-399.
38. Small JV, Rottner K, Kaverina I, (1999) Functional design in the actin cytoskeleton. Curr Opin Cell Biol 11: 54-60.
39. Smilenov LB, Mikhailov A, Pelham RJ, Marcantonio EE, Gundersen GG, (1999) Focal adhesion motility revealed in stationary fibroblasts. Science 286: 1172-1174.
40. Sobel RA, Mitchell ME, (1989) Fibronectin in multiple sclerosis lesions. Am J Pathol 135: 161-168.
41. Sofroniew MV, (2009) Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci 32: 638-647.
42. Sofroniew MV, Vinters HV, (2010) Astrocytes: biology and pathology. Acta Neuropathol 119: 7-35.
43. Song H, Chang W, Lim S, Seo HS, Shim CY, Park S, et al (2007) Tissue transglutaminase is essential for integrin-mediated survival of bone marrow-derived mesenchymal stem cells. Stem Cells 25: 1431-1438.
44. Stenman S, Vaheri A, (1978) Distribution of a major connective tissue protein, fibronectin, in normal human tissues. J Exp Med 147: 1054-1064. (Pubitemid 8318075)
45. Telci D, Wang Z, Li X, Verderio EA, Humphries MJ, Baccarini M, et al (2008) Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem 283: 20937-20947.
46. Tilling T, Engelbertz C, Decker S, Korte D, Huwel S, Galla HJ, (2002) Expression and adhesive properties of basement membrane proteins in cerebral capillary endothelial cell cultures. Cell Tissue Res 310: 19-29.
47. Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mork S, Bo L, (1998) Axonal transection in the lesions of multiple sclerosis. N Engl J Med 338: 278-285.
48. Tucholski J, Lesort M, Johnson GV, (2001) Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells. Neuroscience 102: 481-491.
49. Van Der Laan LJ, De Groot CJ, Elices MJ, Dijkstra CD, (1997) Extracellular matrix proteins expressed by human adult astrocytes in vivo and in vitro: an astrocyte surface protein containing the CS1 domain contributes to binding of lymphoblasts. J Neurosci Res 50: 539-548.
50. Van Der Valk P, De Groot CJ, (2000) Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS. Neuropathol Appl Neurobiol 26: 2-10.
51. Van Horssen J, Dijkstra CD, De Vries HE, (2007) The extracellular matrix in multiple sclerosis pathology. J Neurochem 103: 1293-1301.
52. Verderio EA, Telci D, Okoye A, Melino G, Griffin M, (2003) A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. J Biol Chem 278: 42604-42614.
53. Verderio EA, Johnson T, Griffin M, (2004) Tissue transglutaminase in normal and abnormal wound healing: review article. Amino Acids 26: 387-404.
54. Voskuhl RR, Peterson RS, Song B, Ao Y, Morales LB, Tiwari-Woodruff S, Sofroniew MV, (2009) Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J Neurosci 29: 11511-11522.
55. Wehrle-Haller B, Imhof B, (2002) The inner lives of focal adhesions. Trends Cell Biol 12: 382-389.
56. Yuan L, Choi K, Khosla C, Zheng X, Higashikubo R, Chicoine MR, Rich KM, (2005) Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. Mol Cancer Ther 4: 1293-1302.
57. Yuan L, Siegel M, Choi K, Khosla C, Miller CR, Jackson EN, et al (2007) Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy. Oncogene 26: 2563-2573.
58. Zemskov EA, Loukinova E, Mikhailenko I, Coleman RA, Strickland DK, Belkin AM, (2009) Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase. J Biol Chem 284: 16693-16703.