메뉴 건너뛰기




Volumn 78, Issue 6, 2010, Pages 1079-1087

The human organic anion transporter genes OAT5 and OAT7 are transactivated by hepatocyte nuclear factor-1α (HNF-1α)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA; NUCLEOTIDE; ORGANIC ANION TRANSPORTER; RNA; SMALL INTERFERING RNA;

EID: 78649949040     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.065201     Document Type: Article
Times cited : (27)

References (36)
  • 1
    • 69549103730 scopus 로고    scopus 로고
    • Toward a systems level understanding of organic anion and other multispecific drug transporters: A remote sensing and signaling hypothesis
    • Ahn SY and Nigam SK (2009) Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Mol Pharmacol 76:481-490.
    • (2009) Mol Pharmacol , vol.76 , pp. 481-490
    • Ahn, S.Y.1    Nigam, S.K.2
  • 4
    • 0033921479 scopus 로고    scopus 로고
    • Structure of renal organic anion and cation transporters
    • Burckhardt G and Wolff NA (2000) Structure of renal organic anion and cation transporters. Am J Physiol Renal Physiol 278:F853-F866.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Burckhardt, G.1    Wolff, N.A.2
  • 6
    • 0036401507 scopus 로고    scopus 로고
    • Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters
    • Eraly SA and Nigam SK (2002) Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochem Biophys Res Commun 297:1159-1166.
    • (2002) Biochem Biophys Res Commun , vol.297 , pp. 1159-1166
    • Eraly, S.A.1    Nigam, S.K.2
  • 9
    • 35548966750 scopus 로고    scopus 로고
    • Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family
    • Jacobsson JA, Haitina T, Lindblom J, and Fredriksson R (2007) Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Genomics 90:595-609.
    • (2007) Genomics , vol.90 , pp. 595-609
    • Jacobsson, J.A.1    Haitina, T.2    Lindblom, J.3    Fredriksson, R.4
  • 10
    • 0037371120 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 alpha: A key mediator of the effect of bile acids on gene expression
    • Jung D and Kullak-Ublick GA (2003) Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression. Hepatology 37:622-631.
    • (2003) Hepatology , vol.37 , pp. 622-631
    • Jung, D.1    Kullak-Ublick, G.A.2
  • 11
    • 0035813209 scopus 로고    scopus 로고
    • Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha
    • Jung D, Hagenbuch B, Gresh L, Pontoglio M, Meier PJ, and Kullak-Ublick GA(2001) Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha. J Biol Chem 276:37206-37214.
    • (2001) J Biol Chem , vol.276 , pp. 37206-37214
    • Jung, D.1    Hagenbuch, B.2    Gresh, L.3    Pontoglio, M.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 13
    • 36348965458 scopus 로고    scopus 로고
    • Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation
    • Kikuchi R, Kusuhara H, Hattori N, Kim I, Shiota K, Gonzalez FJ, and Sugiyama Y (2007) Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation. Mol Pharmacol 72:1619-1625.
    • (2007) Mol Pharmacol , vol.72 , pp. 1619-1625
    • Kikuchi, R.1    Kusuhara, H.2    Hattori, N.3    Kim, I.4    Shiota, K.5    Gonzalez, F.J.6    Sugiyama, Y.7
  • 14
    • 33747606242 scopus 로고    scopus 로고
    • Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation
    • Kikuchi R, Kusuhara H, Hattori N, Shiota K, Kim I, Gonzalez FJ, and Sugiyama Y (2006) Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation. Mol Pharmacol 70:887-896.
    • (2006) Mol Pharmacol , vol.70 , pp. 887-896
    • Kikuchi, R.1    Kusuhara, H.2    Hattori, N.3    Shiota, K.4    Kim, I.5    Gonzalez, F.J.6    Sugiyama, Y.7
  • 17
    • 1242295185 scopus 로고    scopus 로고
    • The SLC22 drug transporter family
    • Koepsell H and Endou H (2004) The SLC22 drug transporter family. Pflugers Arch 447:666-676.
    • (2004) Pflugers Arch , vol.447 , pp. 666-676
    • Koepsell, H.1    Endou, H.2
  • 18
    • 33745952758 scopus 로고    scopus 로고
    • Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha
    • Maher JM, Slitt AL, Callaghan TN, Cheng X, Cheung C, Gonzalez FJ, and Klaassen CD (2006) Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha. Biochem Pharmacol 72: 512-522.
    • (2006) Biochem Pharmacol , vol.72 , pp. 512-522
    • Maher, J.M.1    Slitt, A.L.2    Callaghan, T.N.3    Cheng, X.4    Cheung, C.5    Gonzalez, F.J.6    Klaassen, C.D.7
  • 21
    • 0026027585 scopus 로고
    • HNF-1, a member of a novel class of dimerizing homeodomain proteins
    • Mendel DB and Crabtree GR (1991) HNF-1, a member of a novel class of dimerizing homeodomain proteins. J Biol Chem 266:677-680.
    • (1991) J Biol Chem , vol.266 , pp. 677-680
    • Mendel, D.B.1    Crabtree, G.R.2
  • 22
    • 0036190875 scopus 로고    scopus 로고
    • PROMO: Detection of known transcription regulatory elements using species-tailored searches
    • Messeguer X, Escudero R, Farré D, Núñez O, Martínez J, and Albà MM (2002) PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 18:333-334.
    • (2002) Bioinformatics , vol.18 , pp. 333-334
    • Messeguer, X.1    Escudero, R.2    Farré, D.3    Núñez, O.4    Martínez, J.5    Albà, M.M.6
  • 23
    • 70449652284 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1
    • Michels AJ and Hagen TM (2009) Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1. Am J Physiol Cell Physiol 297:C1220-C1227.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Michels, A.J.1    Hagen, T.M.2
  • 24
    • 34447634890 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney
    • Ogasawara K, Terada T, Asaka J, Katsura T, and Inui K (2007) Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney. Am J Physiol Renal Physiol 292:F1819-F1826.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Ogasawara, K.1    Terada, T.2    Asaka, J.3    Katsura, T.4    Inui, K.5
  • 25
    • 17844385785 scopus 로고    scopus 로고
    • The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids
    • Popowski K, Eloranta JJ, Saborowski M, Fried M, Meier PJ, and Kullak-Ublick GA (2005) The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids. Mol Pharmacol 67:1629-1638.
    • (2005) Mol Pharmacol , vol.67 , pp. 1629-1638
    • Popowski, K.1    Eloranta, J.J.2    Saborowski, M.3    Fried, M.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 26
    • 38749113889 scopus 로고    scopus 로고
    • Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta
    • Saji T, Kikuchi R, Kusuhara H, Kim I, Gonzalez FJ, and Sugiyama Y (2008) Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta. J Pharmacol Exp Ther 324:784-790.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 784-790
    • Saji, T.1    Kikuchi, R.2    Kusuhara, H.3    Kim, I.4    Gonzalez, F.J.5    Sugiyama, Y.6
  • 27
    • 57549089243 scopus 로고    scopus 로고
    • Using TESS to predict transcription factor binding sites in DNA sequence
    • Schug J (2008) Using TESS to predict transcription factor binding sites in DNA sequence. Curr Protoc Bioinform 21:2.6.1-2.6.15.
    • (2008) Curr Protoc Bioinform , vol.21
    • Schug, J.1
  • 29
    • 34247400616 scopus 로고    scopus 로고
    • Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate
    • Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, and Kanai Y (2007) Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate. Hepatology 45:1046-1055.
    • (2007) Hepatology , vol.45 , pp. 1046-1055
    • Shin, H.J.1    Anzai, N.2    Enomoto, A.3    He, X.4    Kim Do, K.5    Endou, H.6    Kanai, Y.7
  • 30
    • 0028285029 scopus 로고
    • Molecular cloning and characterization of a novel liver-specific transport protein
    • Simonson GD, Vincent AC, Roberg KJ, Huang Y, and Iwanij V (1994) Molecular cloning and characterization of a novel liver-specific transport protein. J Cell Sci 107:1065-1072.
    • (1994) J Cell Sci , vol.107 , pp. 1065-1072
    • Simonson, G.D.1    Vincent, A.C.2    Roberg, K.J.3    Huang, Y.4    Iwanij, V.5
  • 31
    • 0035658791 scopus 로고    scopus 로고
    • Murine and human type I Na-phosphate cotransporter genes: Structure and promoter activity
    • Soumounou Y, Gauthier C, and Tenenhouse HS (2001) Murine and human type I Na-phosphate cotransporter genes: structure and promoter activity. Am J Physiol Renal Physiol 281:F1082-F1091.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Soumounou, Y.1    Gauthier, C.2    Tenenhouse, H.S.3
  • 32
    • 0034817065 scopus 로고    scopus 로고
    • Isolation of a family of organic anion transporters from human liver and kidney
    • Sun W, Wu RR, van Poelje PD, and Erion MD (2001) Isolation of a family of organic anion transporters from human liver and kidney. Biochem Biophys Res Commun 283:417-422.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 417-422
    • Sun, W.1    Wu, R.R.2    Van Poelje, P.D.3    Erion, M.D.4
  • 33
    • 17444420647 scopus 로고    scopus 로고
    • Organic anion transporter (Slc22a) family members as mediators of toxicity
    • Sweet DH (2005) Organic anion transporter (Slc22a) family members as mediators of toxicity. Toxicol Appl Pharmacol 204:198-215.
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 198-215
    • Sweet, D.H.1
  • 36
    • 3242707822 scopus 로고    scopus 로고
    • Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney
    • Youngblood GL and Sweet DH (2004) Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol 287:F236-F244.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Youngblood, G.L.1    Sweet, D.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.