The specific slow afterhyperpolarization inhibitor UCL2077 is a subtype-selective blocker of the epilepsy associated KCNQ channels

Molecular Pharmacology

Volumn 78, Issue 6, 2010, Pages 1088-1095

  Soh, Heun ^a   Tzingounis, Anastassios V ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (TRIPHENYLMETHYLAMINOMETHYL)PYRIDINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNQ1; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ4; POTASSIUM CHANNEL KCNQ5; TRYPTOPHAN; TRYPTOPHAN 265; UCL 2077; UNCLASSIFIED DRUG;

AFTERHYPERPOLARIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; EPILEPSY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; BENZYLAMINES; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; HEK293 CELLS; HUMANS; KCNQ POTASSIUM CHANNELS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PYRIDINES;

EID: 78649910308     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.066100     Document Type: Article

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